Find $100K+ Professional Jobs in Ohio

Explore high-paying professional opportunities across Ohio with Ladders. Browse vetted roles with salaries of $100,000 or more in major employment centers such as Columbus, Cleveland, Cincinnati, Dayton, and Akron. Whether you’re seeking your next leadership position or a specialized role, discover openings across a range of industries and experience levels.

Explore Ohio’s Major Job Markets

Ohio’s diverse economy creates opportunities in metropolitan hubs and communities throughout the state. Search roles in Columbus, a center for business, healthcare, government, and technology; Cleveland, with opportunities in healthcare, manufacturing, finance, and professional services; and Cincinnati, known for corporate headquarters, consumer goods, logistics, and healthcare. You can also explore positions in Dayton, Akron, Toledo, and other Ohio locations.

Industries and Career Paths

Ohio employers hire experienced professionals across industries including healthcare, technology, engineering, manufacturing, finance, sales, operations, and executive leadership. Available positions and compensation vary by employer, role, location, and qualifications. Use search filters to focus on the fields and opportunities that match your career goals.

Find the Right Ohio Opportunity

Review job requirements, responsibilities, location, and compensation details to identify roles that fit your experience. Keep your profile and résumé current, set up job alerts, and check back often to find newly posted opportunities. Ladders focuses on vetted professional jobs paying $100,000 or more, helping experienced candidates explore their next career move in Ohio.

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1,000+

Jobs in Ohio

Average Salary in USD

Average Salary: $125,316

Sort By: Relevance

$188K - $230K *

Unlock your potential by leading a global sales team, driving growth strategies, and fostering relationships with key OEMs and suppliers in the Commercial Vehicle sector. Collaborate across functions...

RemoteRemote

4 days ago

  •   8 - 10 years exp.  •   Business Services

$75K - $158K *

Join a team that's dedicated to optimizing operations in a fast-paced environment. Support technical and functional stakeholders while ensuring seamless processing and troubleshooting across systems...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$160K - $185K *

Contribute to groundbreaking research in deepfake detection and identity authentication. Drive innovative projects, collaborate with engineers, and translate complex models into scalable solutions, en...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$108K - $130K *

Empower enterprise infrastructures by designing automated workflows for secure, scalable network management. Utilize advanced scripting and automation to optimize systems while leveraging your experti...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$140K - $150K *

Join a team that's dedicated to transforming addiction treatment through telehealth. Collaborate with physicians to provide comprehensive care for patients with substance use disorders, ensuring a sup...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $180K *

Transform digital healthcare services by designing and deploying scalable machine learning models. Collaborate with cross-functional teams to enhance predictive capabilities and ensure compliance with...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Manage cryptologic operations for the F-22 Program, interfacing with military and government stakeholders. Oversee cryptographic hardware and software efforts, ensuring compliance and modernization wh...

Reposted 4 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$108K - $130K *

Drive successful battery energy storage projects by managing installations, ensuring quality, and maintaining customer satisfaction. Collaborate with cross-functional teams to deliver projects on time...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$76K - $95K *

Lead customer success initiatives by building relationships, analyzing data, and advocating for client needs. Manage incidents and provide proactive guidance to enhance adoption and utilization of sol...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Lead and oversee a Work Management group focused on substation construction and maintenance. Collaborate on goals, enhance safety and productivity, and drive continuous improvement in operations and p...

4 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$80K - $95K *

Join a team that's dedicated to enhancing physical security compliance programs, ensuring adherence to regulatory standards, and supporting corporate governance initiatives across multiple sectors. Dr...

4 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$184K - $200K *

Unlock potential by driving the vision and strategy for innovative products that empower independent candidates and enhance user engagement. Collaborate with cross-functional teams to create scalable...

United StatesRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Business Services

$81K - $98K *

Advance your career by leveraging your public health expertise and Salesforce skills to develop impactful solutions. Collaborate with a dedicated team to enhance public health technology, ensuring it...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$86K - $172K *

Empower your career as you design, deploy, and support mainframe systems. Collaborate with teams to troubleshoot and resolve issues while mentoring junior staff in a dynamic environment focused on inf...

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Elevate employee benefits and wellness programs by managing operations and leading a dedicated team. Drive compliance, enhance communication, and foster continuous improvement to align with the Total...

4 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$210K - $250K *

Transform client relationships and drive AI-led growth in the Consumer Products, Manufacturing & Retail sectors. Lead strategic accounts, mentor teams, and shape innovative solutions to enhance busine...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Information Technology

$286K - $295K *

Transform healthcare delivery by providing primary care and medical oversight for residents in developmental centers across Ohio. Collaborate with a multidisciplinary team to enhance health outcomes a...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$325K - $343K *

Lead the charge in shaping the product vision and strategy for consumer panel and behavioral measurement solutions, driving growth through innovative AI-native practices and client collaboration...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Enterprise Technology

$205K - $255K *

Join a team that's shaping the future of data protection by leading the Computer Backup engineering team. Drive technical direction, manage budgets, and enhance collaboration across desktop and backen...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$180K - $215K *

Unlock potential by leading the development of a virtual engagement team to enhance outreach to healthcare professionals, ensuring effective collaboration with field sales and marketing for optimal im...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$105K - $130K *

Elevate patient care by managing clinical support for monitoring systems. Lead diverse teams to enhance customer relationships and ensure effective product utilization post-implementation, driving cli...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Healthcare

$90K *

Deliver exceptional medical sales solutions by building relationships with healthcare professionals, demonstrating products, and exceeding sales goals while ensuring customer satisfaction and effectiv...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $120K *

Join a team that's dedicated to managing the subcontracting lifecycle for government projects. You'll prepare, negotiate, and administer subcontracts while ensuring compliance and fostering strong rel...

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$155K - $259K *

Champion organizational success by leading HR strategies, guiding senior leaders, and fostering an inclusive workplace. Leverage HR expertise to enhance talent management and drive business performanc...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Finance & Insurance

$80K - $120K *

Elevate your career by managing critical construction projects in data centers and hospitals. Collaborate with diverse teams to ensure project success while mentoring others and driving innovative sol...

4 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Ohio?question toggle

    Ohio listings may include professional, management, executive, and specialized positions in fields such as healthcare, technology, engineering, manufacturing, finance, sales, and operations. Roles and salaries vary by employer and qualifications.

  • Which Ohio cities have high-paying job opportunities?question toggle

    Opportunities may be available in Columbus, Cleveland, Cincinnati, Dayton, Akron, Toledo, and other Ohio communities. Availability changes as employers post and fill positions.

  • Are the Ohio jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional job opportunities with salaries of $100,000 or more. Review each listing for its specific compensation and requirements.

  • How can I find a suitable job in Ohio?question toggle

    Search by location, job title, industry, or other relevant filters. Compare the qualifications, responsibilities, location, and compensation listed for each role, and keep your résumé and profile up to date.