Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Average Salary: $114,677
CNC Tooling Sales and Application Engineer
$80K - $95K *
Join a team that's driving innovation in CNC tooling sales by leveraging your machining expertise to enhance customer relationships and boost productivity. This role combines technical knowledge with...
1 week ago
Lead Software Engineer, AI Platform
$164K - $240K *
Collaborate with cross-functional teams to build AI infrastructure, ensure reliability and security, and guide technical direction while fostering engineer development. Lead innovative projects that e...
Reposted 1 week ago
Case Manager - Registered Nurse - South Region
$60K - $129K *
Partner with us to enhance health outcomes through a comprehensive, collaborative case management approach, engaging with clients and healthcare providers to optimize care plans and ensure quality ser...
Reposted 1 week ago
$80K - $95K *
Champion workplace safety by leading EHS initiatives, conducting audits, and mentoring staff. Collaborate with management and external agencies to enhance health and safety programs, ensuring complian...
1 week ago
$120K - $165K *
Elevate your career as a Scientific Product Owner, driving innovation in clinical genomics software. Collaborate with cross-functional teams to translate scientific needs into actionable requirements...
1 week ago
Global Regulatory Affairs Manager
$110K - $130K *
Drive your career forward by joining our Global Regulatory Team, where you'll define and execute strategies for rare disease treatments, ensuring alignment with health authorities and contributing to...
1 week ago
$150K - $180K *
Unlock potential by leading a dynamic team in Workforce Management and Quality Assurance. Drive operational excellence, vendor partnerships, and innovative strategies to enhance service delivery and p...
1 week ago
$160K - $190K *
Lead your career with a global approach to compensation strategies, driving pay equity, job architecture, and operations compliance across regions. Oversee a high-performing team, ensuring alignment w...
Reposted 1 week ago
$125K - $150K *
Elevate operational excellence by leading strategic initiatives across diverse service lines. Drive continuous improvement and ensure effective execution of complex projects while fostering collaborat...
1 week ago
Executive Assistant to CEO - Concord Hospitality Enterprises - Raleigh, NC
$79K - $89K *
Join a dynamic team as you provide high-level support to the CEO, managing complex schedules, facilitating communications, and coordinating executive initiatives to ensure seamless operations within t...
1 week ago
Regional Sales Manager - Power
$90K - $110K *
Engage with powersports dealerships to expand financing partnerships, drive sales growth, and enhance dealer relationships. Utilize market insights to develop strategic plans and support dealer onboar...
1 week ago
$81K - $138K *
Unlock potential by joining a dynamic team that enhances federal data ecosystems. Support customer inquiries, streamline operations, and drive improvements in a cloud-based analytics environment, ensu...
1 week ago
Revenue Cycle Enterprise Partner
$133K - $191K *
Transform revenue cycle operations by leading strategic initiatives, optimizing performance, and fostering collaboration across business units to enhance service delivery and achieve organizational go...
1 week ago
Associate Optometrist - Wake Forest, FL - Target Optical
$100K - $120K *
Unlock potential by providing exceptional optometric care within a flexible, independent practice, collaborating directly with a subleasing doctor to enhance patient experiences and maintain professio...
Reposted 1 week ago
Mission Systems S/4HANA Wave Deployment Lead, Sr. Manager (REMOTE)
$132K - $251K *
Advance S/4HANA deployment as the key liaison, driving site preparation, cross-functional coordination, and seamless go-live execution while minimizing operational disruptions across assigned Mission...
Reposted 1 week ago
$97K - $133K *
Join a dynamic team to drive sales growth and enhance customer relationships. Manage key accounts, collaborate with cross-functional teams, and ensure exceptional service while achieving ambitious sal...
1 week ago
AI Application Development Engineer
$80K - $95K *
Accelerate progress at the forefront of AI development by designing and enhancing enterprise applications. Collaborate with cross-functional teams to deliver innovative solutions that address real bus...
1 week ago
$95K - $115K *
Transform operational efficiency by leading strategic projects in reverse logistics and refurbishment. Collaborate with cross-functional teams to enhance processes, optimize workflows, and drive conti...
Reposted 1 week ago
Workday Services Account Executive
$110K - $130K *
Join a dynamic team to drive new business acquisition in a high-growth market. Leverage your expertise in full-cycle sales to build strategic partnerships and achieve uncapped earning potential while...
1 week ago
Director, Provider Network Operations
$108K - $184K *
Champion strategic initiatives in Provider Network Operations, overseeing key functions like Provider Relations and Credentialing. Drive performance and compliance across Medicaid, Medicare, and Comme...
1 week ago
$90K - $112K *
Transform your career by supporting operational excellence in customs compliance for a pioneering electric vehicle brand. Engage with diverse stakeholders to ensure accurate import/export processes wh...
1 week ago
Lead, Sustainability & Stewardships Programs
$150K - $181K *
Join a team that's driving sustainability initiatives to transform corporate responsibility. You'll manage programs that align with environmental goals, ensuring measurable impact and compliance while...
1 week ago
Area Manager Specialty Atlantic Region
$110K - $130K *
Drive business growth by promoting products, managing key accounts, and achieving sales targets. Build relationships with clients and KOLs while ensuring compliance with company policies and contribut...
1 week ago
Area Manager Specialty Atlantic Region
$110K - $130K *
Advance your career by driving sales and fostering relationships in the pharmaceutical sector. Collaborate with key accounts and promote innovative products while achieving territory targets and suppo...
1 week ago
$74K - $102K *
Elevate your career by leading a dynamic team to enhance customer experiences and drive sales. In this role, you'll manage store operations, develop talent, and implement innovative strategies in a fa...
1 week ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.