Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,677

Sort By: Relevance

$80K - $95K *

Join a team that's driving innovation in CNC tooling sales by leveraging your machining expertise to enhance customer relationships and boost productivity. This role combines technical knowledge with...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$164K - $240K *

Collaborate with cross-functional teams to build AI infrastructure, ensure reliability and security, and guide technical direction while fostering engineer development. Lead innovative projects that e...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$60K - $129K *

Partner with us to enhance health outcomes through a comprehensive, collaborative case management approach, engaging with clients and healthcare providers to optimize care plans and ensure quality ser...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Champion workplace safety by leading EHS initiatives, conducting audits, and mentoring staff. Collaborate with management and external agencies to enhance health and safety programs, ensuring complian...

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$120K - $165K *

Elevate your career as a Scientific Product Owner, driving innovation in clinical genomics software. Collaborate with cross-functional teams to translate scientific needs into actionable requirements...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Drive your career forward by joining our Global Regulatory Team, where you'll define and execute strategies for rare disease treatments, ensuring alignment with health authorities and contributing to...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Unlock potential by leading a dynamic team in Workforce Management and Quality Assurance. Drive operational excellence, vendor partnerships, and innovative strategies to enhance service delivery and p...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $190K *

Lead your career with a global approach to compensation strategies, driving pay equity, job architecture, and operations compliance across regions. Oversee a high-performing team, ensuring alignment w...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Food & Beverages

$125K - $150K *

Elevate operational excellence by leading strategic initiatives across diverse service lines. Drive continuous improvement and ensure effective execution of complex projects while fostering collaborat...

1 week ago

  •   8 - 10 years exp.  •   Staffing

$79K - $89K *

Join a dynamic team as you provide high-level support to the CEO, managing complex schedules, facilitating communications, and coordinating executive initiatives to ensure seamless operations within t...

1 week ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$90K - $110K *

Engage with powersports dealerships to expand financing partnerships, drive sales growth, and enhance dealer relationships. Utilize market insights to develop strategic plans and support dealer onboar...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$81K - $138K *

Unlock potential by joining a dynamic team that enhances federal data ecosystems. Support customer inquiries, streamline operations, and drive improvements in a cloud-based analytics environment, ensu...

1 week ago

  •   Less than 5 years exp.  •   Business Services

$133K - $191K *

Transform revenue cycle operations by leading strategic initiatives, optimizing performance, and fostering collaboration across business units to enhance service delivery and achieve organizational go...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Unlock potential by providing exceptional optometric care within a flexible, independent practice, collaborating directly with a subleasing doctor to enhance patient experiences and maintain professio...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$132K - $251K *

Advance S/4HANA deployment as the key liaison, driving site preparation, cross-functional coordination, and seamless go-live execution while minimizing operational disruptions across assigned Mission...

North Carolina, USRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$97K - $133K *

Join a dynamic team to drive sales growth and enhance customer relationships. Manage key accounts, collaborate with cross-functional teams, and ensure exceptional service while achieving ambitious sal...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Accelerate progress at the forefront of AI development by designing and enhancing enterprise applications. Collaborate with cross-functional teams to deliver innovative solutions that address real bus...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Transform operational efficiency by leading strategic projects in reverse logistics and refurbishment. Collaborate with cross-functional teams to enhance processes, optimize workflows, and drive conti...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Join a dynamic team to drive new business acquisition in a high-growth market. Leverage your expertise in full-cycle sales to build strategic partnerships and achieve uncapped earning potential while...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$108K - $184K *

Champion strategic initiatives in Provider Network Operations, overseeing key functions like Provider Relations and Credentialing. Drive performance and compliance across Medicaid, Medicare, and Comme...

North Carolina, USRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$90K - $112K *

Transform your career by supporting operational excellence in customs compliance for a pioneering electric vehicle brand. Engage with diverse stakeholders to ensure accurate import/export processes wh...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$150K - $181K *

Join a team that's driving sustainability initiatives to transform corporate responsibility. You'll manage programs that align with environmental goals, ensuring measurable impact and compliance while...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Drive business growth by promoting products, managing key accounts, and achieving sales targets. Build relationships with clients and KOLs while ensuring compliance with company policies and contribut...

Raleigh, NCRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Advance your career by driving sales and fostering relationships in the pharmaceutical sector. Collaborate with key accounts and promote innovative products while achieving territory targets and suppo...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$74K - $102K *

Elevate your career by leading a dynamic team to enhance customer experiences and drive sales. In this role, you'll manage store operations, develop talent, and implement innovative strategies in a fa...

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.