Discover professional opportunities across North Carolina with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking their next career move, from senior individual-contributor positions to executive leadership. Explore openings in major employment centers such as Charlotte, Raleigh, Durham, and Greensboro, as well as opportunities across the state.
North Carolina offers a diverse job market shaped by financial services, technology, healthcare, life sciences, manufacturing, and professional services. Charlotte is a major hub for banking and corporate leadership, while the Raleigh-Durham region is known for technology, research, healthcare, and life sciences. Opportunities may also be available in Greensboro, Winston-Salem, Asheville, and other communities.
Search for experienced-level roles in areas such as technology, finance, operations, sales, marketing, healthcare, engineering, and general management. Job titles, qualifications, work arrangements, and compensation vary by employer. Review each listing for details and identify opportunities that match your background and career goals.
Ladders focuses on vetted professional jobs paying $100,000 or more, helping experienced candidates explore opportunities aligned with their expertise. Use this page to browse North Carolina openings, compare roles, and discover your next step. Listings and availability change, so check back regularly for new opportunities.
Average Salary: $115,032
Senior Director, Business Development and Partnerships
$160K - $200K *
Drive growth by leading strategic partnerships in healthcare tech. Collaborate with executives to shape joint strategies, negotiate impactful deals, and operationalize go-to-market initiatives that en...
3 days ago
$190K - $249K *
Join a team that's bridging technical solutions with client needs, driving digital transformation. Leverage your expertise to build relationships, influence decisions, and ensure customer success thro...
3 days ago
Senior Account-Based Marketing (ABM) Manager
$110K - $130K *
Transform demand generation strategies in the Consumer & Life Sciences sectors. Lead initiatives to create impactful marketing campaigns, enhance customer engagement, and collaborate with cross-functi...
Reposted 3 days ago
Training Specialist, Holly Springs
$77K - $144K *
Oversee the onboarding program and training processes, ensuring compliance and efficiency. Collaborate with stakeholders to enhance LMS functionality and support continuous improvement initiatives whi...
3 days ago
$85K - $100K *
Champion patient recovery by delivering individualized, evidence-based physical therapy. Collaborate with a dedicated team to enhance mobility and improve lives, while fostering professional growth an...
3 days ago
Audit Project Manager - Payment Services
$98K - $115K *
Join a team that's dedicated to delivering innovative payment solutions while leading audit engagements. As an Audit Project Manager, you'll supervise staff, ensure quality work, and collaborate acros...
3 days ago
Sr. Manager, Transformation & Value Creation
$142K - $202K *
Unlock commercial potential by executing transformation workstreams, collaborating with cross-functional teams, and delivering strategic insights to drive measurable results in a healthcare-focused en...
3 days ago
Principal Product Manager, AI Workflows
$150K - $180K *
Elevate AI experiences from concept to value by collaborating with engineering and design teams. Drive strategy, build prototypes, and make data-driven decisions to enhance user engagement and product...
3 days ago
$110K - $130K *
Help us shape the future of federal security architecture by developing integrated designs and compliance strategies that protect sensitive information while ensuring reliable business operations acro...
3 days ago
$160K - $200K *
Transform client relationships by driving business growth, securing profitable projects, and leveraging market access expertise. Lead teams to exceed expectations while identifying industry trends and...
3 days ago
Staff Systems Engineer - Architecture & Interfaces
$165K - $220K *
Join a team that's redefining avionics systems engineering by translating customer needs into innovative architectures and requirements. Collaborate across domains to deliver high-quality solutions in...
3 days ago
$66K - $105K *
Join a team that's dedicated to delivering exceptional patient care through comprehensive assessments, individualized care plans, and effective collaboration with healthcare professionals to enhance p...
3 days ago
Senior Business Development Director - RWD Licensing
$150K - $180K *
Drive your career with a strategic sales leadership role focused on enterprise growth in healthcare. Lead complex business development efforts, build executive relationships, and shape solutions that...
3 days ago
$130K - $155K *
Lead the AI/ML product strategy across multiple business units, driving integration and data-centric solutions that enhance customer value and revenue growth through innovative workflows and collabora...
3 days ago
Executive Director, Manufacturing
$175K - $210K *
Lead operational excellence in biopharmaceutical manufacturing, overseeing GMP processes, technology transfers, and clinical supply. Drive strategic initiatives, manage CDMO relationships, and build a...
3 days ago
Civil Site Lead, Power Delivery - Remote (U.S.)
$95K - $115K *
Lead the charge in civil engineering for transmission and substation projects. Oversee site work, ensure compliance, and mentor engineers while collaborating with multidisciplinary teams to deliver hi...
3 days ago
Civil Site Lead, Power Delivery - Remote (U.S.)
$108K - $130K *
Elevate your career by leading civil site projects for transmission and substations. Drive engineering excellence, manage site compliance, and collaborate with multidisciplinary teams to deliver innov...
3 days ago
RevOps Strategic Initiatives Manager
$106K - $146K *
Shape the future of our operations by leading a dynamic team to optimize Quote-to-Cash strategies, enhance analytics, and design streamlined workflows, all while collaborating across functions to driv...
Reposted 3 days ago
$280K - $350K *
Unlock potential by leading a high-performing Enterprise sales team to drive revenue growth, mentor talent, and align strategies across departments, ensuring success in complex B2B SaaS solutions for...
3 days ago
Mid-Market Customer Success Manager
$80K - $95K *
Lead the charge in driving customer success for mid-market accounts, ensuring adoption and renewals while identifying growth opportunities. Collaborate cross-functionally to enhance customer experienc...
3 days ago
$68K - $115K *
Grow client relationships and drive sales in a remote field role, focusing on the Mid-Atlantic market. Engage with clients to understand their needs, resolve concerns, and expand market awareness whil...
3 days ago
$110K - $130K *
Champion the evolution of organic search strategies across enterprise software brands. Lead initiatives in technical SEO, content optimization, and AI-driven search, driving visibility and revenue whi...
3 days ago
Portfolio Manager, Manufacturing & Transportation Solutions
$160K - $246K *
Pioneer innovative portfolio strategies for Manufacturing and Transportation solutions. Lead a dynamic team, drive product innovation, and collaborate across global functions to enhance offerings and...
3 days ago
Senior Manager, Engineering - Onboarding
$217K - $264K *
Lead and optimize the engineering team to enhance customer onboarding and lifecycle management, ensuring robust risk management and compliance across products while fostering a high-performing, inclus...
3 days ago
Business Development Representative - Autonomous Systems
$120K - $140K *
Join a dynamic team to drive business growth by identifying and cultivating strategic partnerships. Leverage market insights to develop tailored solutions that meet mission needs and enhance client re...
3 days ago
What types of $100K-plus jobs can I find in North Carolina?
Listings may include senior and executive opportunities across technology, finance, healthcare, life sciences, manufacturing, sales, operations, engineering, and other professional fields. Availability and requirements vary by employer.
Which North Carolina cities have high-paying job opportunities?
Opportunities may be found in Charlotte, Raleigh, Durham, Greensboro, Winston-Salem, Asheville, and other parts of the state. The location of each position is shown in its listing.
Are North Carolina jobs on Ladders vetted?
Ladders focuses on vetted professional jobs that pay $100,000 or more. Review each job listing for the employer, qualifications, compensation information, and application details.
Can I find remote or hybrid jobs based in North Carolina?
Some employers offer remote or hybrid arrangements, but work options differ by role. Check the individual listing for its location and workplace requirements.
How often should I check for new North Carolina jobs?
Listings change as employers add or fill positions. Check back regularly to see newly available opportunities that match your experience and salary goals.