Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,967
$250K - $300K *
Join a dynamic team as you drive enterprise sales across mid-market to Fortune 500 accounts. Own the entire sales cycle, engage multi-stakeholder buying committees, and leverage AI tools to redefine b...
4 days ago
Principal Technical Account Manager
$190K - $220K *
Shape the future of global accounts by aligning technical strategy with business vision. Engage with C-suite stakeholders to drive innovation, define KPIs, and integrate AI analytics into service deli...
4 days ago
Regional Director, B Lab U.S. & Canada
$200K - $240K *
Drive the growth and impact of the B Corp movement in the US and Canada, leading strategic initiatives, fostering partnerships, and enhancing community engagement to position purpose-driven business a...
4 days ago
$80K - $95K *
Elevate nursing excellence by directing patient care activities and collaborating with teams to enhance service delivery, optimize resources, and ensure compliance with standards, fostering satisfacti...
4 days ago
Technical Account Manager, Commercial
$130K - $160K *
Join a team that's dedicated to optimizing customer success through technical expertise. As a trusted advisor, you'll manage relationships, guide deployments, and ensure seamless adoption for federal...
4 days ago
Salesforce Higher Ed Solution Architect
$120K - $145K *
Transform higher education through innovative Salesforce solutions, guiding institutions in architecture design, implementation, and best practices to enhance student engagement and operational effici...
4 days ago
Auto and General Liability Claims Specialist
$107K - $161K *
Join a team that's dedicated to managing complex Auto and General Liability claims. You'll handle high exposure cases, oversee litigation, and develop resolution strategies while collaborating with va...
4 days ago
$160K - $200K *
Drive strategic growth and operational excellence in cardiology, fostering physician partnerships and overseeing clinical and financial performance to enhance patient care and organizational success...
4 days ago
$83K - $133K *
Optimize customer interactions by managing order entry, tracking, and support activities across local business units and agent accounts, ensuring timely delivery and effective communication in a dynam...
4 days ago
$175K - $210K *
Unlock potential by leading a transformative sales organization across diverse markets. Drive growth through strategic sales initiatives, team development, and robust forecasting, while transitioning...
4 days ago
$190K - $230K *
Lead the accounting and financial reporting functions within a growing healthcare organization. Drive integrity across multiple entities, ensure compliance, and strategize cash management while suppor...
Reposted 4 days ago
$135K - $160K *
Lead the strategic design and management of comprehensive benefits programs, ensuring alignment with employee needs and company objectives. Drive innovation and compliance while enhancing employee eng...
4 days ago
Business Development Manager - Acute
$95K - $115K *
Grow your career by driving revenue growth in the acute care market through new customer acquisition and account expansion. Manage the full sales lifecycle while collaborating with internal teams to d...
4 days ago
Senior Director, Head of R&D Governance and Portfolio Management
$228K - $342K *
Advance the future of R&D governance and portfolio management by leading strategic decision-making processes, optimizing operational efficiency, and ensuring seamless progression of therapeutic assets...
4 days ago
Account Manager, Life Science, Public Health Labs (East Coast)
$105K - $120K *
Engage with public health labs to enhance customer satisfaction and drive sales. Collaborate with cross-functional teams to execute market strategies and foster relationships with key opinion leaders...
4 days ago
Quality Assurance Engineer - Conversational AI & Voice Testing
$95K - $115K *
Drive quality assurance for innovative conversational AI solutions, ensuring reliability and accuracy across voice applications and customer engagement platforms. Collaborate with cross-functional tea...
4 days ago
$100K - $120K *
Elevate your career by designing and optimizing EpicCare Ambulatory workflows. Collaborate with clinicians to enhance EHR functionality, troubleshoot issues, and ensure seamless operations across heal...
4 days ago
Software Engineer - Special Projects and Innovation
$99K - $120K *
Join a team that's redefining innovation in software engineering for critical facilities. You'll design and deliver cutting-edge applications and data solutions, driving projects from concept to deplo...
4 days ago
$113K - $125K *
Drive product strategy and outcomes in a senior role, focusing on educational equity and data-driven impact. Collaborate with cross-functional teams to shape product direction, prioritize initiatives...
4 days ago
$95K - $115K *
Lead the charge in optimizing operational activities within the DHMS program, ensuring compliance and driving continuous improvement. Collaborate with stakeholders to implement effective strategies an...
4 days ago
Key Account Leader, Small Cities East
$110K - $140K *
Join a dynamic team as you drive sales in the public safety sector, managing a diverse territory. Leverage AI tools to identify opportunities, close deals, and build lasting relationships with agencie...
4 days ago
Big Data Developer (Black Lotus Labs)
$132K - $176K *
Shape the future of cybersecurity by leading big data solutions to identify and disrupt malicious threats. Collaborate with cross-functional teams, innovate with cutting-edge technologies, and drive t...
Reposted 4 days ago
Implementation Manager, Financial Services
$100K - $120K *
Accelerate client success by owning the onboarding and rollout for enterprise clients, ensuring smooth transitions from purchase to sustained usage. Collaborate with cross-functional teams to drive ad...
4 days ago
Senior Product Manager, Commitments
$135K - $160K *
Lead the strategy for the Commitments product, enhancing customer compliance tracking through AI. Collaborate with cross-functional teams to drive adoption and deliver impactful solutions that address...
4 days ago
$135K - $160K *
Transform healthcare technology by owning core products, driving architectural decisions, and ensuring high-quality code. Collaborate across teams to deliver impactful solutions that enhance patient c...
4 days ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.