Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,967
Security Analyst (Governance and Trust)
$89K - $105K *
Lead the charge in enhancing customer trust through security assurance and AI governance. This role focuses on maintaining accurate security documentation and optimizing AI agents to support governanc...
Reposted 4 days ago
Regional Sales Director (Remote)
$150K - $180K *
Lead and inspire a high-performing sales team to drive revenue growth and expand customer relationships in a competitive cybersecurity landscape, while developing strategic initiatives and fostering e...
4 days ago
Network Solutions Engineer - Fort Meade, MD
$108K - $130K *
Innovate solutions for network modernization by leading design, testing, and implementation efforts. Collaborate with stakeholders to ensure seamless integration of Ciena products, enhancing performan...
4 days ago
Director, HR Business Partner - Corporate Functions
$119K - $190K *
Shape the future of our Corporate Functions by partnering with senior leaders to drive talent strategy, organizational effectiveness, and leadership development. Leverage data and insights to influenc...
4 days ago
$80K - $95K *
Accelerate progress at a dynamic automotive SaaS company by owning the Mid-Market segment. Drive new business with multi-location auto repair groups, shaping strategies and building a scalable sales p...
4 days ago
National Quality Performance Manager (Remote)
$90K - $110K *
Advance quality performance initiatives by collaborating across departments to enhance healthcare outcomes, manage data analytics, and ensure compliance with regulatory standards, driving continuous i...
4 days ago
$69K - $119K *
Transform the landscape of clinical documentation by educating and mentoring teams, ensuring compliance, and enhancing documentation accuracy to optimize patient care and coding outcomes...
4 days ago
Captive Business Development Manager - River Oak Risk
$80K - $95K *
Drive new business generation in captive management solutions, focusing on multifamily risk and large P&C alternatives. Build relationships with brokers and multifamily owners while managing the full...
4 days ago
$155K - $185K *
Join a dynamic team to oversee security operations, incident response, and automation initiatives. Collaborate with cross-functional teams to enhance security practices and develop tools that streamli...
4 days ago
$82K - $132K *
Unlock potential in revenue cycle management by leading innovative solutions, optimizing processes, and collaborating across departments to enhance operational efficiency and maximize revenue impact...
4 days ago
Senior Software Engineer, Data Engineering Platform
$186K - $218K *
Innovate with a collaborative team as you build scalable blockchain infrastructure, design APIs, and streamline complex data processes. Your contributions will enhance system reliability and performan...
Reposted 4 days ago
$106K - $167K *
Pioneer growth as a Senior Field Sales Executive, driving success in the Eastern US. Manage key accounts, develop strategies, and build relationships to enhance customer satisfaction and achieve sales...
4 days ago
Senior Power BI Technical Consultant
$110K - $130K *
Unlock potential by designing and deploying Power BI solutions that transform data into actionable insights. Collaborate with stakeholders to create scalable models and enhance reporting capabilities...
4 days ago
Lead Platform Engineer - Infrastructure & Backend
$150K - $185K *
Take ownership of our cloud and backend infrastructure, driving technical direction and improvements. Lead a team to ensure reliability and scalability of systems supporting our games and analytics, w...
4 days ago
Sr. Revenue Enablement Manager, Groups
$115K - $160K *
Drive your career forward by enabling the Groups team to excel in revenue generation through innovative training, AI-driven tools, and strategic partnerships, ensuring consistent performance and growt...
4 days ago
Staff Software Engineer, Search Backend
$200K - $250K *
Elevate the search experience by designing and evolving a robust backend system that powers millions of searches. Collaborate across teams to enhance scalability, reliability, and maintainability whil...
4 days ago
Senior Credit Products Specialist - Power & Renewables
$138K - $219K *
Transform credit strategy by leading complex commercial credit relationships, mentoring junior professionals, and ensuring portfolio health through innovative deal structuring and proactive risk manag...
4 days ago
DIRECTOR, OPERATIONAL INNOVATION & ENABLEMENT
$160K - $180K *
Lead organizational capability by bridging strategy and execution across diverse hospitality operations. Drive scalable frameworks and change management to enhance performance and sustain innovation a...
4 days ago
$302K - $483K *
Transform the future of secure platforms by leading engineering strategy and execution. Drive innovation, operational excellence, and team performance to empower autonomy and accountability across the...
4 days ago
Principal AI Solutions Architect
$220K - $310K *
Empower businesses by architecting and deploying innovative AI solutions that leverage graph databases and LLMs. Collaborate with stakeholders to transform complex data challenges into impactful appli...
4 days ago
$100K - $120K *
Unlock potential by designing and building robust data pipelines for healthcare transactions. Collaborate with partners to ensure seamless integration and reliability of data systems, enhancing operat...
4 days ago
$69K - $118K *
Lead the charge in managing curriculum adoptions, collaborating with stakeholders to ensure successful outcomes in K-12 education. Elevate adoption processes and quality, supporting cross-functional t...
Reposted 4 days ago
Key Account Leader, Small Cities West
$110K - $140K *
Grow your career with us by leading public safety drone sales in small cities. Own your territory, drive full-cycle deals, and collaborate with cross-functional teams to deliver innovative solutions t...
4 days ago
Principal Engineer - Database Platform Engineering & SRE
$152K - $223K *
Drive operational transformation and cloud readiness by leading database modernization initiatives, improving reliability and engineering excellence through automation and best practices while mentori...
Reposted 4 days ago
Director, Strategy and Operations
$150K - $180K *
Drive strategic planning and operational excellence for a dynamic Marketing & Communications team. Own budgeting, resource management, and cross-functional partnerships while leading initiatives that...
4 days ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.