Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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1,000+

Jobs in Mississippi

Average Salary in USD

Average Salary: $111,063

Sort By: Relevance

$110K - $130K *

Drive growth by managing end-to-end sales cycles in the Energy sector, enhancing customer relationships, and executing strategies to exceed targets while collaborating with cross-functional teams for...

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  •   Less than 5 years exp.  •   Enterprise Technology

$68K - $105K *

Help us lead enterprise-wide incident responses and internal investigations into misconduct, ensuring compliance and effective fraud detection while collaborating across departments to uphold organiza...

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  •   5 - 7 years exp.  •   Healthcare

$75K - $108K *

Unlock potential by managing diverse research projects, coordinating operations, and supporting data analysis. Collaborate with interdisciplinary teams to drive impactful educational initiatives and e...

United StatesRemote

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  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$120K - $150K *

Transform the delivery landscape by leading cross-functional initiatives, mentoring analysts, and driving strategic solutions across business units and external partners. Engage deeply in project exec...

United StatesRemote

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  •   5 - 7 years exp.  •   Finance & Insurance

$240K - $379K *

Champion innovative government programs by leading multidisciplinary teams to deploy cutting-edge NVIDIA solutions. Collaborate with diverse stakeholders to ensure successful execution and drive impac...

United StatesRemote

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  •   8 - 10 years exp.  •   Manufacturing & Automotive

$83K - $104K *

Lead the charge in managing complex client programs, driving operational excellence and strategic direction while fostering strong stakeholder relationships and ensuring exceptional service delivery...

United StatesRemote

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  •   8 - 10 years exp.  •   Enterprise Technology

$188K - $265K *

Accelerate progress at the forefront of AI infrastructure by leading technical direction, ensuring platform architecture meets company ambitions, and fostering collaboration across engineering teams f...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Enterprise Technology

$113K - $155K *

Champion quality excellence by executing business programs across manufacturing sites, collaborating with cross-functional teams to enhance product standards, manage consumer insights, and drive conti...

United StatesRemote

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  •   Less than 5 years exp.  •   Food & Beverages

$214K - $309K *

Unlock potential by leading the design and implementation of advanced identity solutions for AI agents. Collaborate across teams to build scalable frameworks and drive technical excellence in a dynami...

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  •   11 - 15 years exp.  •   Telecommunications & Hardware

$200K *

Drive technical excellence by translating creative visions into actionable plans. Oversee pre-production, CAD drafting, and on-site execution, ensuring projects are delivered safely, on time, and with...

United StatesRemote

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  •   5 - 7 years exp.  •   Business Services

$180K - $220K *

Lead the charge in transforming identity security marketing strategies, driving growth and market leadership. Oversee a dynamic team to enhance product positioning, execute go-to-market plans, and sha...

United StatesRemote

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  •   Less than 5 years exp.  •   Information Technology

$95K - $125K *

Transform safety culture by leading project teams in compliance and incident prevention. Develop safety plans, conduct audits, and facilitate training to ensure a safe work environment on large constr...

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  •   Less than 5 years exp.  •   Energy & Utilities

$130K - $157K *

Engineer innovative power system models and analyses to optimize utility-scale solar and storage solutions, working collaboratively with global teams to ensure compliance and advance SMA's technical c...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Energy & Utilities

$164K - $240K *

Lead global procurement initiatives, optimizing sourcing strategies and cost structures to ensure high-quality products at competitive prices, while enhancing supply chain efficiencies and aligning wi...

United StatesRemote

Reposted today

  •   11 - 15 years exp.  •   Retail & Consumer Goods

$164K - $240K *

Lead strategic procurement initiatives to achieve optimal cost structures and maintain supply continuity. Collaborate across teams to drive innovation in sourcing and enhance quality standards while a...

United StatesRemote

Reposted today

  •   11 - 15 years exp.  •   Retail & Consumer Goods

$124K - $138K *

Shape the future of vendor relations by managing the RTV process, negotiating effectively, and collaborating cross-functionally to maximize recovery value and streamline operations within the supply c...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$137K - $185K *

Elevate procurement strategies by analyzing supplier performance and collaborating cross-functionally to ensure material availability and operational efficiency, driving continuous improvement in supp...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$80K - $95K *

Champion cross-functional projects to enhance operational efficiency and achieve organizational goals. Lead initiatives from planning to completion, ensuring timely delivery within scope and budget wh...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$180K - $200K *

Drive the future of AI capability by leading the development of role-specific tools and workflows, ensuring measurable impact and adoption across teams. Collaborate with HR to enhance learning and ope...

United StatesRemote

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  •   5 - 7 years exp.  •   Real Estate & Construction

$138K - $200K *

Drive the strategic direction of enterprise security infrastructure, leading teams to design, implement, and optimize security solutions across on-premises, cloud, and hybrid environments while ensuri...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$92K - $139K *

Drive exceptional customer success by managing a complex portfolio of Enterprise accounts, enhancing software value through strategic relationships and problem-solving. Influence industry revenue and...

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Reposted today

  •   Less than 5 years exp.  •   Information Technology

$125K - $150K *

Accelerate progress at building a world-class AI Receptionist partner ecosystem, driving revenue and customer success through strategic enablement programs. Collaborate cross-functionally to enhance p...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$90K - $110K *

Elevate patient care by diagnosing illnesses, prescribing treatments, and coordinating health plans. Collaborate with healthcare teams to ensure comprehensive patient assessments and promote health th...

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  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Join our team as a Senior Customer Success Engineer, where you'll tackle complex technical challenges, mentor peers, and enhance processes to elevate customer success across our product portfolio...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$105K - $150K *

Transform your career by joining a dynamic team focused on enhancing security compliance for cloud services. Leverage your expertise in IT security to assess architectures, guide vendors, and ensure a...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.