Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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1,000+

Jobs in Mississippi

Average Salary in USD

Average Salary: $111,063

Sort By: Relevance

$100K - $120K *

Help us bridge legacy systems with modern data integration by analyzing, documenting, and translating existing application logic for migration. Collaborate with engineers to ensure seamless transition...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$125K - $150K *

Empower teams by providing technical leadership in data science and AI/ML, driving enterprise data modernization initiatives. Collaborate with stakeholders to design and deliver impactful decision-mak...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $180K *

Unlock potential by leading technical sales engagements in quantum computing, guiding customers through complex challenges, and delivering tailored solutions across diverse industries while collaborat...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $115K *

Drive complex capital projects from concept to execution, ensuring safety, quality, and efficiency. Collaborate across teams to meet operational goals while leading multiple initiatives in a dynamic m...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$159K - $218K *

Transform sales performance by leading a dynamic team to exceed revenue goals across diverse laboratory solutions in a defined region, fostering customer relationships and driving strategic initiative...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $111K *

Transform the landscape of diagnostic imaging sales by driving competitive conversions and expanding market share. Collaborate with key stakeholders to achieve business objectives and cultivate long-t...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $121K *

Join us to drive sales growth by identifying new business opportunities and nurturing client relationships. Leverage your technical and business acumen to influence stakeholders and close deals while...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $121K *

Join a team that's driving sales growth by leveraging technology to meet client needs. Engage with stakeholders at all levels, identify new opportunities, and cultivate relationships to enhance busine...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$115K - $130K *

Join a team that's driving strategic technology initiatives across business domains. As a Program Manager, you'll align projects with objectives, manage interdependencies, and ensure successful delive...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Transportation

$95K - $115K *

Join a team that's transforming People Operations by leading strategic HR initiatives, enhancing processes, and serving as a trusted advisor to managers while ensuring compliance and operational excel...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Food & Beverages

$113K - $188K *

Join a dynamic team to design and develop high-performance ETL solutions, integrating data from diverse sources. Collaborate with cross-functional teams to optimize data workflows and ensure complianc...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$102K - $170K *

Lead the charge in full-stack development, collaborating on enterprise modernization with Microservices. Deliver high-quality software, mentor engineers, and ensure best practices for cloud technologi...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$150K - $190K *

Unlock your potential as a Senior Turbine Aerodynamicist, leading innovative turbine design and analysis for aircraft and industrial engines. Collaborate across teams to drive strategic improvements a...

RemoteRemote

2 weeks ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$168K - $181K *

Lead the charge in developing innovative AWS cloud solutions for scoring capabilities. Collaborate with cross-functional teams to enhance system reliability and efficiency, while mentoring junior engi...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$120K - $130K *

Manage financial reporting and internal controls, leading a team to ensure accurate, timely financial statements while driving continuous improvement and collaboration across departments to support bu...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$105K - $130K *

Shape the future of analytics by leading reporting initiatives and managing client relationships. Drive implementation strategies, gather requirements, and deliver impactful dashboard solutions using...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$70K - $95K *

Transform patient care by leading clinical activities in a Wound Care Center. Collaborate with healthcare teams to enhance healing outcomes, ensure quality improvement, and provide staff development w...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $250K *

Transform clinical trials by ensuring patient safety and scientific integrity. Collaborate with stakeholders to uphold regulatory standards and optimize study protocols, while providing expert medical...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$79K - $142K *

Elevate data-driven decision-making by transforming HR data into strategic insights. Leverage analytical skills and tools to enhance workforce performance and support HR initiatives, ensuring data acc...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$120K - $150K *

Join a team that's shaping the future of consulting in P&C insurance. Lead client engagements, ensure quality standards, and foster long-term relationships while driving business growth and mentoring...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$65K - $120K *

Join a dynamic team as you lead impactful fundraising campaigns for Catholic parishes. Collaborate with diverse stakeholders, manage projects, and drive community-focused initiatives while developing...

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$80K - $110K *

Unlock growth by driving high-impact engagements with C-suite security leaders. Utilize cutting-edge sales tools and collaborate seamlessly with Account Executives to generate valuable pipelines and f...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $120K *

Develop strategic relationships and drive lubricant sales in New England and New York. Lead account planning, assess distributor needs, and achieve sales targets while collaborating with internal team...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$130K - $180K *

Support business growth in the North American nuclear power market by building relationships, identifying opportunities, and leveraging technical expertise to deliver reliable power solutions to custo...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Lead patient care initiatives by providing pharmaceutical expertise, counseling, and immunizations. Engage with the community to enhance health outcomes while ensuring compliance with regulations and...

2 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.