Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,961
Hospital Inpatient Coding Manager
$77K - $121K *
Join a team that's redefining coding excellence by leading operational strategies, managing staff performance, and ensuring compliance in inpatient coding processes to enhance efficiency and quality a...
2 weeks ago
Senior Corporate Development and Planning Analyst
$95K - $115K *
Take ownership of financial and operational analysis for strategic initiatives, delivering critical insights and reporting to support executive decision-making while driving accuracy and efficiency in...
Reposted 2 weeks ago
Research Computing Services Manager
$110K - $130K *
Unlock potential by managing research computing infrastructure, guiding teams, and ensuring efficient operations. Collaborate with a dedicated team to drive innovations in patient care while enjoying...
2 weeks ago
$120K - $145K *
Elevate healthcare through strategic AI product management, driving innovation and lifecycle management of AI solutions. Collaborate cross-functionally to align business objectives with customer needs...
2 weeks ago
$95K - $125K *
Optimize HR excellence in the Midwest by driving talent development, enhancing employee engagement, and supporting General Managers in fostering a high-performance culture. Act as a strategic partner...
Reposted 2 weeks ago
$53K - $110K *
Unlock potential by leveraging data analysis to support public health initiatives. Collaborate on quantitative and qualitative evaluations, ensuring data integrity and contributing to impactful progra...
2 weeks ago
$150K - $160K *
Lead the charge in managing complex programs within Navy Medicine, ensuring seamless integration of systems and exceptional client support while overseeing personnel and contract performance for optim...
2 weeks ago
$110K - $130K *
Empower enterprise growth by identifying and nurturing relationships with C-suite executives. Drive consultative sales, tailor solutions, and collaborate across teams to enhance client experiences and...
2 weeks ago
$87K - $135K *
Drive your career forward by leading systems engineering for a cloud-based enterprise system. Engage in architecture development, integration, and modernization efforts while ensuring security and ope...
2 weeks ago
$95K - $115K *
Champion customer acquisition and revenue growth by leading paid search strategies, optimizing campaigns, and mentoring a team. Drive performance through data analysis and cross-functional collaborati...
2 weeks ago
Senior Principal Software Engineer
$243K - $318K *
Elevate your career by providing technical leadership across Dev AI platforms. Shape architectural strategies, drive cross-organizational initiatives, and enhance engineering quality while collaborati...
2 weeks ago
Account Executive, Solutions (PA)
$80K - $95K *
Accelerate progress at K–12 schools by driving new business and customer success in western PA. Build relationships with education leaders while executing strategic territory plans to achieve sales go...
2 weeks ago
$144K - $189K *
Unlock potential by leading product innovation in clinical genomics. Shape tools for case management and data workflows, ensuring efficiency and quality while collaborating with lab directors and engi...
2 weeks ago
Senior Legal Counsel, Corporate & Commercial
$150K - $180K *
Innovate with us to build scalable legal frameworks that support rapid growth. As a strategic advisor, you'll manage complex agreements, corporate governance, and leverage AI to enhance operational ef...
2 weeks ago
$275K - $325K *
Lead the charge in building and managing a construction banking sector, driving strategy, partnerships, and product development while overseeing P&L and fostering key relationships to establish Flex a...
2 weeks ago
$110K - $130K *
Empower decision-making by utilizing data-driven insights to enhance operations, supporting growth through statistical modeling and AI techniques while maintaining compliance in a complex regulatory e...
Reposted 2 weeks ago
$120K - $145K *
Lead the charge in advancing enterprise automation capabilities, driving quality engineering innovation, and influencing strategic decisions across a rapidly growing organization, enhancing software r...
Reposted 2 weeks ago
Senior Analyst, Technical Implementation
$89K - $133K *
Empower success by leading healthcare technology implementations, optimizing workflows, and ensuring compliance. Collaborate across teams to guarantee smooth integrations and enhance system functional...
Reposted 2 weeks ago
Vulnerability Management Manager
$150K - $200K *
Lead the charge in vulnerability management, driving remediation efforts and enhancing security across cloud environments. Collaborate with cross-functional teams to reduce risks and improve operation...
2 weeks ago
$185K - $210K *
Lead the charge in optimizing revenue operations by enhancing forecasting, analytics, and sales strategies to drive growth and accountability across North America’s sales teams, ensuring alignment and...
2 weeks ago
$95K - $115K *
Join a team that's redefining network solutions by designing, implementing, and supporting advanced LAN, WAN, and wireless systems. Collaborate with cross-functional leaders to enhance network strateg...
2 weeks ago
RN Clinical Team Director - Hospice
$80K - $95K *
Transform patient care as a Hospice RN Team Director, leading a dedicated team to deliver compassionate support. Oversee assessments, manage staff, and enhance quality of care while fostering a collab...
2 weeks ago
$180K - $205K *
Drive financial excellence by delivering insights and analysis for the Field Service organization. Collaborate across departments to enhance forecasting, budgeting, and operational efficiency while su...
2 weeks ago
$108K - $157K *
Optimize data-driven strategies by transforming raw analytics into actionable insights. Collaborate with cross-functional teams to enhance marketplace dynamics and drive measurable business outcomes i...
2 weeks ago
$122K - $203K *
Empower teams by leading data governance initiatives, enhancing data quality, and fostering collaboration across business domains. Drive operational excellence and ensure compliance while developing a...
2 weeks ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.