Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

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1,000+

Jobs in Mississippi

Average Salary in USD

Average Salary: $110,961

Sort By: Relevance

$80K - $95K *

Champion quality excellence by leading cross-functional teams to enhance delivery performance, customer satisfaction, and operational processes. Drive continuous improvement initiatives and ensure com...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Lead strategic management of real estate transactions, ensuring optimal outcomes for clients through collaboration and innovative solutions across a diverse portfolio of commercial properties...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K - $130K *

Empower our Enterprise customers by enhancing product adoption and health. Collaborate with cross-functional teams to deliver tailored solutions, ensuring exceptional experiences for high-growth organ...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$163K - $224K *

Join a team that's redefining People Operations by leading global service delivery, enhancing employee experiences, and driving operational excellence across Talent Acquisition and People processes fo...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $135K *

Elevate vendor sales through strategic partnerships, driving growth and profitability. Foster relationships with vendor teams, enable partner success, and align on revenue goals to enhance market pres...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$160K - $200K *

Accelerate capital relationships by building networks with allocators and family offices. Drive fund raises and support M&A mandates while educating investors on private market structures. Own your im...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$97K - $131K *

Shape the future of tribal nations by leading audit processes, ensuring financial integrity, and nurturing client relationships. Drive team performance and provide insights that make a meaningful diff...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$80K - $95K *

Deliver impactful multi-channel demand generation campaigns while creating engaging content that drives qualified leads. Collaborate with cross-functional teams to optimize performance and achieve pip...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Join a dynamic team to create and implement control systems, providing technical support and mentoring while driving project success and ensuring optimal performance of HVAC and automation solutions...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$180K - $240K *

Lead strategic business initiatives by building relationships with senior executives to drive revenue growth in life sciences. Develop actionable plans to identify opportunities and enhance market pos...

United StatesRemote

Reposted 2 weeks ago

  •   15+ years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Drive sales growth by building strong vendor relationships and enabling partners. You'll align with internal teams to deliver impactful solutions, ensuring swift onboarding and maximizing revenue thro...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$107K - $133K *

Engage in business development and sales growth by identifying opportunities, building relationships, and expanding market share in the Southeast region. Utilize a consultative approach to drive susta...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$125K - $150K *

Lead the charge in monitoring transactional risk for banking and treasury services, ensuring effective fraud detection and credit risk management across multiple program layers while driving resolutio...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$80K - $95K *

Join a team that's dedicated to enhancing employee benefits through expert administration, compliance, and continuous improvement. Collaborate with HR, Payroll, and external partners to ensure excepti...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Staffing

$170K - $200K *

Transform your career by leading strategic relationships with key national partners, driving significant sales growth while navigating complex market dynamics. Collaborate closely with leadership to t...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $172K *

Lead the charge in revolutionizing the data center market by driving new business. Utilize your technical expertise and commercial insight to develop strategies that enhance revenue and establish stro...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$138K - $165K *

Elevate our product management efforts by driving innovation in cybersecurity. Collaborate with cross-functional teams to deliver impactful data-driven analytics, leveraging user insights and industry...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $225K *

Lead and mentor a dynamic Security Operations team, overseeing incident response and SOC improvements while driving hands-on investigations and AI-assisted workflows to enhance security posture and op...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $105K *

Support complex, high-value customer renewals while leading strategic negotiations. Engage at C-suite level to build relationships, drive consensus, and mentor team members towards continual improveme...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$160K - $192K *

Lead the charge in driving commercial performance by engaging healthcare providers, building relationships, and executing territory business plans to ensure patient access to innovative therapies and...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $192K *

Drive commercial performance by engaging healthcare providers and executing territory plans. Collaborate with cross-functional teams to support product launches and ensure patient access to innovative...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $120K *

Unlock your potential as a Solutions Engineer, guiding sales teams with expert network security advice, conducting training sessions, and supporting customer needs while driving professional services...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $120K *

Unlock your potential by guiding higher education leadership searches. Collaborate with institutional leaders to define candidate profiles, engage top talent, and manage the selection process, ensurin...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $120K *

Unlock potential by leading strategic planning for a water utility. Collaborate with stakeholders to assess priorities, design actionable plans, and ensure alignment with long-term goals while enhanci...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$110K - $130K *

Join a dynamic team as a strategic HR Business Partner, supporting global entities. Drive employee relations, performance management, and culture integration while guiding HR initiatives across divers...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.