Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

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1,000+

Jobs in Mississippi

Average Salary in USD

Average Salary: $110,961

Sort By: Relevance

$80K - $95K *

Join us to lead the School of Health Sciences, driving strategic growth and academic excellence while fostering partnerships and enhancing student success in a dynamic educational environment...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Drive strategic leadership and operational excellence in health sciences education, overseeing diverse programs and fostering partnerships to enhance student outcomes and workforce alignment in a dyna...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Lead strategic initiatives and operational oversight for a diverse suite of health science programs, fostering academic excellence and workforce alignment while ensuring compliance and enhancing stude...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Join us in providing strategic leadership and oversight for diverse healthcare programs, fostering innovation and academic excellence while enhancing student outcomes and community partnerships in a d...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$165K - $228K *

Lead and empower a dynamic product management team, driving strategy, commercialization, and market engagement for innovative healthcare solutions while fostering collaboration across global business...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$89K - $133K *

Drive innovative automation solutions for generator control systems, collaborating with cross-functional teams to enhance power system performance from design to commissioning, ensuring customer satis...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$89K - $133K *

Shape the future of power systems by delivering innovative automation and control solutions for generator control switchgear systems, collaborating with cross-functional teams to execute projects from...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$89K - $133K *

Transform power systems by delivering innovative automation solutions. Collaborate with cross-functional teams to design, implement, and support generator control systems, ensuring excellence from con...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$150K - $200K *

Transform your career by driving wealth management growth across the Pacific West. Collaborate with advisors and leaders to enhance product adoption and sales, leveraging market insights and relations...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$126K - $227K *

Lead the charge in manufacturing excellence by providing expert DFM and NPI support. Collaborate with teams to resolve technical issues, enhance processes, and drive continuous improvement while ensur...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$150K - $180K *

Advance your career by leading strategic partnerships, optimizing relationships, and driving revenue growth. Collaborate across teams to enhance product capabilities and market reach while managing a...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$153K - $253K *

Empower our team by leading underwriting strategies for commercial accounts. Drive profitability and growth while fostering relationships with agents and brokers. Your expertise will shape our approac...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$144K - $205K *

Lead the charge in enhancing AP World Languages and Arts by ensuring assessment quality, driving strategic growth, and managing a diverse team. Collaborate with leadership to influence enterprise deci...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$144K - $205K *

Elevate the quality and impact of AP Social Science courses by leading a diverse team, driving strategic initiatives, and ensuring assessment integrity. Collaborate across departments to enhance stude...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$152K - $228K *

Advance healthcare by leveraging your expertise as a Medical Science Liaison, fostering relationships with healthcare practitioners and key opinion leaders to drive scientific exchange and support str...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$152K - $228K *

Empower healthcare through scientific expertise as you build relationships with HCPs and KOLs. Drive medical strategies and support clinical research in the rare neurology field, enhancing patient out...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$152K - $228K *

Unlock your potential as a Medical Science Liaison, driving scientific engagement and collaboration with healthcare professionals in the rare neurology space. Leverage your expertise to support strate...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$152K - $228K *

Elevate your career as a Medical Science Liaison, driving scientific engagement and collaboration with healthcare professionals in the rare neurology field while supporting strategic medical objective...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$152K - $228K *

Transform healthcare by leveraging your scientific expertise to build relationships with HCPs and KOLs. Drive medical strategies and support clinical initiatives in the rare neurology space, ensuring...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$152K - $228K *

Lead the charge in advancing scientific knowledge and relationships with healthcare practitioners in the rare neurology field, driving strategic medical objectives and fostering collaboration across t...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$152K - $228K *

Build strategic relationships with healthcare practitioners to support medical objectives in rare neurology. Leverage scientific expertise to communicate effectively and drive collaboration within the...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$152K - $228K *

Advance your career as a Medical Science Liaison, leveraging your expertise to build relationships with healthcare professionals and drive scientific engagement in the rare neurology space across the...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$152K - $228K *

Engage with healthcare professionals to drive scientific exchange and support medical objectives. Leverage clinical expertise and business acumen to build relationships and facilitate collaboration wi...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$152K - $228K *

Shape the future of rare neurology by managing HCP relationships and driving scientific engagement. Leverage your clinical expertise to support medical objectives and foster collaboration within a dyn...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Join us to leverage your analytical expertise in Amazon and Commerce data, driving actionable insights and advanced reporting. Collaborate with cross-functional teams to enhance decision-making and op...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Media

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.