Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,961
Dean of the School of Health Sciences
$80K - $95K *
Join us to lead the School of Health Sciences, driving strategic growth and academic excellence while fostering partnerships and enhancing student success in a dynamic educational environment...
Reposted 1 week ago
Dean of the School of Health Sciences
$80K - $95K *
Drive strategic leadership and operational excellence in health sciences education, overseeing diverse programs and fostering partnerships to enhance student outcomes and workforce alignment in a dyna...
Reposted 1 week ago
Dean of the School of Health Sciences
$80K - $95K *
Lead strategic initiatives and operational oversight for a diverse suite of health science programs, fostering academic excellence and workforce alignment while ensuring compliance and enhancing stude...
Reposted 1 week ago
Dean of the School of Health Sciences
$80K - $95K *
Join us in providing strategic leadership and oversight for diverse healthcare programs, fostering innovation and academic excellence while enhancing student outcomes and community partnerships in a d...
Reposted 1 week ago
Director of Product Marketing, XP Radiography and Fluoroscopy (RF)
$165K - $228K *
Lead and empower a dynamic product management team, driving strategy, commercialization, and market engagement for innovative healthcare solutions while fostering collaboration across global business...
1 week ago
Automation & Controls Engineer - Critical Power Systems (Remote)
$89K - $133K *
Drive innovative automation solutions for generator control systems, collaborating with cross-functional teams to enhance power system performance from design to commissioning, ensuring customer satis...
1 week ago
Electrical Engineer – Critical Power Systems (Remote)
$89K - $133K *
Shape the future of power systems by delivering innovative automation and control solutions for generator control switchgear systems, collaborating with cross-functional teams to execute projects from...
1 week ago
Electrical Controls Engineer - Critical Power Systems (Remote)
$89K - $133K *
Transform power systems by delivering innovative automation solutions. Collaborate with cross-functional teams to design, implement, and support generator control systems, ensuring excellence from con...
1 week ago
RVP Wealth Management - Pacific West
$150K - $200K *
Transform your career by driving wealth management growth across the Pacific West. Collaborate with advisors and leaders to enhance product adoption and sales, leveraging market insights and relations...
1 week ago
Regional Manufacturing Engineering Lead (Remote)
$126K - $227K *
Lead the charge in manufacturing excellence by providing expert DFM and NPI support. Collaborate with teams to resolve technical issues, enhance processes, and drive continuous improvement while ensur...
1 week ago
Senior Director of Strategic Partnerships
$150K - $180K *
Advance your career by leading strategic partnerships, optimizing relationships, and driving revenue growth. Collaborate across teams to enhance product capabilities and market reach while managing a...
1 week ago
Managing Director - Commercial Accounts
$153K - $253K *
Empower our team by leading underwriting strategies for commercial accounts. Drive profitability and growth while fostering relationships with agents and brokers. Your expertise will shape our approac...
1 week ago
Executive Director, AP World Languages and Arts Department Head, Curriculum & Assessment
$144K - $205K *
Lead the charge in enhancing AP World Languages and Arts by ensuring assessment quality, driving strategic growth, and managing a diverse team. Collaborate with leadership to influence enterprise deci...
1 week ago
Executive Director, AP Social Science Department Head, Curriculum & Assessment
$144K - $205K *
Elevate the quality and impact of AP Social Science courses by leading a diverse team, driving strategic initiatives, and ensuring assessment integrity. Collaborate across departments to enhance stude...
1 week ago
Medical Science Liaison, Rare Neurology, Southeast
$152K - $228K *
Advance healthcare by leveraging your expertise as a Medical Science Liaison, fostering relationships with healthcare practitioners and key opinion leaders to drive scientific exchange and support str...
1 week ago
Medical Science Liaison, Rare Neurology, Southeast
$152K - $228K *
Empower healthcare through scientific expertise as you build relationships with HCPs and KOLs. Drive medical strategies and support clinical research in the rare neurology field, enhancing patient out...
1 week ago
Medical Science Liaison, Rare Neurology, Southeast
$152K - $228K *
Unlock your potential as a Medical Science Liaison, driving scientific engagement and collaboration with healthcare professionals in the rare neurology space. Leverage your expertise to support strate...
1 week ago
Medical Science Liaison, Rare Neurology, Southeast
$152K - $228K *
Elevate your career as a Medical Science Liaison, driving scientific engagement and collaboration with healthcare professionals in the rare neurology field while supporting strategic medical objective...
1 week ago
Medical Science Liaison, Rare Neurology, Southeast
$152K - $228K *
Transform healthcare by leveraging your scientific expertise to build relationships with HCPs and KOLs. Drive medical strategies and support clinical initiatives in the rare neurology space, ensuring...
1 week ago
Medical Science Liaison, Rare Neurology, Southeast
$152K - $228K *
Lead the charge in advancing scientific knowledge and relationships with healthcare practitioners in the rare neurology field, driving strategic medical objectives and fostering collaboration across t...
1 week ago
Medical Science Liaison, Rare Neurology, Southeast
$152K - $228K *
Build strategic relationships with healthcare practitioners to support medical objectives in rare neurology. Leverage scientific expertise to communicate effectively and drive collaboration within the...
1 week ago
Medical Science Liaison, Rare Neurology, Southeast
$152K - $228K *
Advance your career as a Medical Science Liaison, leveraging your expertise to build relationships with healthcare professionals and drive scientific engagement in the rare neurology space across the...
1 week ago
Medical Science Liaison, Rare Neurology, Southeast
$152K - $228K *
Engage with healthcare professionals to drive scientific exchange and support medical objectives. Leverage clinical expertise and business acumen to build relationships and facilitate collaboration wi...
1 week ago
Medical Science Liaison, Rare Neurology, Southeast
$152K - $228K *
Shape the future of rare neurology by managing HCP relationships and driving scientific engagement. Leverage your clinical expertise to support medical objectives and foster collaboration within a dyn...
1 week ago
Insights Lead Analyst, Amazon Focus
$100K - $120K *
Join us to leverage your analytical expertise in Amazon and Commerce data, driving actionable insights and advanced reporting. Collaborate with cross-functional teams to enhance decision-making and op...
1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.