Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,961
$80K - $128K *
Elevate our proposal visual strategy by crafting compelling graphics and narratives. Collaborate with diverse teams to transform complex ideas into engaging visuals for federal submissions, enhancing...
1 week ago
$160K - $220K *
Champion safety and environmental excellence by leading EHS strategies across manufacturing operations, ensuring compliance, reducing risks, and fostering a proactive culture of safety and sustainabil...
1 week ago
$110K - $130K *
Elevate your career by joining a dynamic team as a Sr. Product Owner, driving AI-enabled solutions across product portfolios. Collaborate with stakeholders to enhance customer value and modernize busi...
1 week ago
Principal Platform/Software Engineer
$150K - $180K *
Lead the charge in designing and implementing innovative software systems for cutting-edge healthcare SaaS platforms, driving technical excellence and strategic collaboration across teams to achieve i...
Reposted 1 week ago
IOM Technologist-Traveler East Coast
$80K - $95K *
Champion patient safety by monitoring neuromuscular function during surgeries. Collaborate with surgical teams to ensure optimal outcomes through real-time data analysis and communication, making a si...
1 week ago
$74K - $139K *
Elevate operational excellence by leading the SPOC department, ensuring compliance and efficiency in loss mitigation services. Drive performance, workforce planning, and process improvements while fos...
1 week ago
Senior Sales Manager - Pet Food
$110K - $130K *
Transform client relationships by driving sales growth and strategic initiatives for the Pet Food sector. Lead efforts to exceed performance goals while collaborating with cross-functional teams and m...
1 week ago
Sr Execution Business Partner Practitioner – EBP Center of Excellence
$160K - $170K *
Drive excellence in program execution by mentoring leaders, optimizing performance, and ensuring compliance. Transform data into insights for proactive decision-making, enhancing customer satisfaction...
1 week ago
Information Security Consultant
$100K - $120K *
Advance your career as a Compliance Consultant, supporting diverse clients in enhancing their information security and compliance frameworks. Collaborate on audits, risk assessments, and governance pr...
Reposted 1 week ago
$125K - $170K *
Lead the charge in managing complex contracts for a major program, ensuring compliance and strategic alignment. Collaborate with teams to develop proposals, negotiate terms, and maintain strong relati...
1 week ago
$120K - $150K *
Join a dynamic team to shape corporate strategy by translating insights into actionable recommendations that drive growth. Collaborate cross-functionally to identify opportunities and influence decisi...
1 week ago
People Technology Senior Specialist - Reporting & Analytics
$120K - $140K *
Unlock your potential as a Lead People Technology Analyst, driving data-driven insights and reporting solutions that empower HR decision-making and enhance workforce strategies across the organization...
1 week ago
$87K - $135K *
Lead the charge in Agile delivery as a Scrum Master, guiding cross-functional teams to enhance customer support and IT services. Foster collaboration, remove impediments, and ensure alignment with gov...
1 week ago
$120K - $145K *
Lead the charge in database operations, ensuring optimal performance and security for mission-critical systems. Oversee a technical team while aligning with federal standards and integrating with deve...
1 week ago
Linux Web Server Administrator
$110K - $130K *
Transform your career by managing and optimizing Linux web server environments. Leverage your expertise in Apache, Tomcat, and NGINX to enhance performance, security, and reliability in a fully remote...
1 week ago
Management Analyst (Human Resources)
$80K - $95K *
Help us enhance federal human capital operations through independent analysis, strategic recommendations, and effective program delivery. Collaborate on data-driven insights to improve efficiency and...
Reposted 1 week ago
$95K - $115K *
Empower your career by providing analytic support for performance improvement and labor productivity initiatives. Collaborate with leaders to develop standards, enhance data integrity, and optimize be...
1 week ago
$80K - $100K *
Lead the charge in delivering comprehensive audit services, enhancing client relationships, and mentoring junior staff while managing multiple engagements in a dynamic, results-driven environment...
1 week ago
U.S. Sales & Tax Senior Accountant
$101K - $137K *
Join a dynamic team to support U.S. sales and use tax compliance, manage audits, and enhance workflows. Collaborate with internal teams and third-party providers to ensure accurate tax filings and mai...
1 week ago
Principle Machine Learning Engineer
$160K - $200K *
Lead the technical direction for AI agent quality, defining metrics and evaluation systems. Collaborate with cross-functional teams to enhance agent performance and ensure quality in production enviro...
1 week ago
Senior Machine Learning Engineer
$150K - $180K *
Design and optimize evaluation systems for AI agents, enhancing performance and quality through innovative metrics and benchmarks. Collaborate with cross-functional teams to ensure agents meet user ne...
1 week ago
Vice President Field Operations
$172K - $223K *
Champion operational excellence as a strategic leader, driving performance and financial results across the PacWest Region while ensuring safety, quality, and compliance in a mission-driven environmen...
1 week ago
Chief, Division of Pediatric Nephrology
$210K - $250K *
Unlock potential by leading strategic initiatives to expand faculty and enhance academic excellence. This role involves mentorship, vision, and collaboration to meet diverse educational and clinical n...
Reposted 1 week ago
Director, Client Coding Integration
$97K - $145K *
Join a team that's dedicated to ensuring accurate coding and compliance for clinical services, leveraging your expertise to enhance revenue cycle management and contribute to optimal healthcare outcom...
Reposted 1 week ago
Community Engagement Manager, Data Centers (Indiana & Kentucky)
$265K - $295K *
Lead the charge in community engagement, fostering trusted relationships with local stakeholders to ensure Anthropic's infrastructure projects benefit Indiana and Kentucky communities throughout their...
1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.