Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,961
Senior Cloud Infrastructure Engineer
$150K - $175K *
Shape the cloud infrastructure landscape by ensuring security, scalability, and efficiency. Collaborate with engineers to build resilient systems and drive best practices, enabling smooth deployment a...
Reposted 1 week ago
Group Director, Client Media Solutions
$175K - $200K *
Lead the charge in developing integrated media strategies and client partnerships across pharmaceutical and life sciences accounts, driving business growth and ensuring exceptional delivery and client...
1 week ago
Principal AI Software Engineer
$150K - $180K *
Lead the charge in designing and deploying AI systems that enhance productivity and customer experience across multiple departments, driving innovation and efficiency through advanced AI capabilities...
1 week ago
Senior Staff Performance Marketing Manager
$157K - $228K *
Lead the charge in B2B performance marketing strategy, driving measurable pipeline and revenue growth through multi-channel paid initiatives. Collaborate with cross-functional teams to optimize campai...
1 week ago
$80K - $95K *
Elevate your career with an impactful role where you'll drive end-to-end recruitment for U.S.-based startups, manage talent pipelines, and enhance candidate engagement in a fast-paced environment...
Reposted 1 week ago
$370K - $490K *
Join a dynamic team to lead enterprise retail sales, driving strategic growth across diverse categories. Coach senior Account Executives, manage complex deals, and build relationships with top merchan...
1 week ago
Customer Development Specialist - North Central
$68K - $93K *
Unlock your potential as you drive sales and build relationships in the veterinary sector. Utilize digital tools and strategic planning to enhance customer experiences and achieve sales targets in a d...
1 week ago
Customer Development Specialist - Dallas/Ft. Worth, TX
$68K - $93K *
Join a team that's dedicated to driving sales in the pet health sector. You'll build relationships with veterinary practices, leverage digital tools, and execute strategies to maximize sales performan...
1 week ago
Customer Development Specialist - Chesapeake
$68K - $93K *
Unlock potential by driving sales through strategic customer engagement and relationship management. Utilize digital tools and territory management to enhance customer experiences and achieve sales ta...
1 week ago
Customer Development Specialist - Great Plains
$68K - $93K *
Join a team that's dedicated to driving sales and enhancing customer relationships in the veterinary sector. Utilize innovative strategies and digital tools to maximize performance and deliver excepti...
1 week ago
Customer Development Specialist - Great Lakes (MI)
$68K - $93K *
Empower veterinary practices by driving sales through relationship building, strategic planning, and digital engagement. Utilize CRM tools to enhance customer experiences and achieve sales targets in...
1 week ago
$150K - $180K *
Develop and optimize scalable web applications using TypeScript, Java, and Node.js. Collaborate with teams to deliver innovative AI-powered solutions while ensuring code quality and performance in a d...
1 week ago
$110K - $130K *
Elevate your career by architecting a cutting-edge digital growth engine. Drive enterprise lead generation through innovative strategies, leveraging AI and data analytics to optimize performance and m...
1 week ago
Salesforce Quality Assurance Tester
$120K - $130K *
Join a dynamic team to enhance Salesforce capabilities in a federal environment. Collaborate with government leads to optimize testing processes, ensuring quality and compliance throughout the Salesfo...
1 week ago
$120K - $145K *
Lead the charge in multidisciplinary design delivery for data center projects, ensuring buildable, cost-effective designs from planning through construction. Collaborate with teams to meet tenant need...
1 week ago
Senior Director/VP - Translational Medicine & Pharmacology
$210K - $250K *
Drive the translational strategy for immunology therapies, focusing on biomarker development and clinical pharmacology. Collaborate cross-functionally to advance pipeline assets and support regulatory...
1 week ago
$80K - $95K *
Grow your career with us as a key Associate Sales Manager, driving sales in advanced ceramic powders for diverse industries. Collaborate with customers to identify needs, deliver solutions, and achiev...
Reposted 1 week ago
Senior Account Manager, Higher Education and Research
$200K - $356K *
Champion growth by engaging with top research institutions to promote NVIDIA’s technology, driving strategic partnerships in a dynamic environment while navigating university ecosystems and advancing...
Reposted 1 week ago
Manager of Applied AI, Solutions Support Engineering
$135K - $160K *
Champion an AI-first approach by leading a team of developers to enhance internal tools and automation for technical support, driving innovation and efficiency in case resolution while actively engagi...
1 week ago
$115K - $192K *
Engineer trusted, reusable data products by transforming architectural designs and business requirements into production-grade solutions. Collaborate with cross-functional teams to deliver innovative...
1 week ago
Specialist, Software Engineering
$110K - $183K *
Innovate the future of healthcare technology by developing scalable applications that streamline specialty prescriptions. Collaborate with a skilled team to enhance user experience and drive efficienc...
1 week ago
$80K - $95K *
Unlock potential by driving outbound sales strategies, managing a robust pipeline, and converting prospects into clients. Collaborate with healthcare companies to identify opportunities and achieve qu...
1 week ago
Senior Product Marketing Manager - Lifecycle & Customer Communications
$135K - $166K *
Drive our end-to-end Lifecycle strategy and customer communications journey, leveraging data and AI to enhance engagement across multiple channels. Collaborate cross-functionally to optimize conversio...
1 week ago
Product Owner / Senior Product Owner - Engineering Tools
$78K - $98K *
Shape the future of AEC workflows by leading product ownership and Agile delivery for an Engineering Tools team. Collaborate with cross-functional stakeholders to prioritize needs, validate outcomes...
1 week ago
Digital Product Manager Expert - Security Platforms
$120K - $193K *
Join a team that's redefining security product management by leading the strategy and delivery of innovative security solutions. Drive efficiency and compliance while enhancing developer experiences t...
1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.