Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,974
Product Builder, Merchant Portal
$104K - $145K *
Elevate product development by defining, designing, and prototyping features for a merchant portal, leveraging AI tools and user feedback to enhance payment processing solutions rapidly and effectivel...
1 week ago
Sr. Analyst, Pricing Analytics
$89K - $134K *
Explore your potential as a key analytical consultant, leveraging data to optimize drug pricing and enhance pharmacy relationships while collaborating across multiple functions to drive strategic grow...
1 week ago
Director, AI Platforms & Engineering
$105K - $165K *
Shape the future of AI platforms by leading strategy, architecture, and engineering for scalable, secure solutions. Drive innovation while ensuring compliance and operational excellence across enterpr...
1 week ago
$136K - $187K *
Lead patient education and support initiatives for individuals affected by generalized Myasthenia Gravis. Collaborate with caregivers and healthcare teams to enhance treatment coordination and empower...
1 week ago
$136K - $187K *
Join a team that's dedicated to empowering patients with generalized Myasthenia Gravis through education and support. As a key point of contact, you'll coordinate care, provide resources, and ensure c...
1 week ago
$136K - $187K *
Unlock potential by serving as a vital resource for patients and caregivers, providing education and support for managing generalized Myasthenia Gravis while coordinating treatment and navigating insu...
1 week ago
$168K - $231K *
Join a dynamic team to lead Nurse Case Managers, enhancing patient support and education throughout treatment journeys while ensuring compliance and quality in case management processes...
1 week ago
Supplier Quality Program Manager - Remote
$134K - $176K *
Lead the development and execution of a national supplier quality program, ensuring compliance and fostering strong supplier relationships to enhance operational efficiency and project success across...
1 week ago
Director, National Recruitment
$74K - $131K *
Empower recruitment excellence by leading strategic campaigns nationwide, building strong partnerships, and enhancing team performance. Drive impactful initiatives while adapting to diverse recruitmen...
1 week ago
Power BI / Insurance Analytics Developer
$95K - $115K *
Drive impactful analytics by designing and maintaining Power BI dashboards, leveraging SQL expertise to extract insights from complex datasets, and applying insurance knowledge to enhance reporting so...
1 week ago
Senior Developer- Python Full Stack
$120K - $145K *
Drive the design and implementation of innovative pricing tools, enhancing market readiness and efficiency. Collaborate across teams to establish technical standards and mentor junior developers while...
1 week ago
Regional Hospice RN (AZ/ CA/ NM)
$98K - $112K *
Join a dedicated team providing compassionate hospice care across multiple locations. Collaborate with interdisciplinary teams to ensure quality patient outcomes while adapting to diverse clinical env...
1 week ago
$135K - $216K *
Advance the deployment of MHS GENESIS across multiple sites, ensuring seamless integration and performance outcomes while managing stakeholder relationships and project deliverables throughout the lif...
1 week ago
$135K - $216K *
Lead the charge in integrating DOD MP-ICAM solutions, focusing on CAC/PIV, SAML, and Active Directory. Collaborate with cybersecurity teams to enhance identity controls and support privileged-access w...
1 week ago
Data Migration Lead / Architect
$112K - $179K *
Architect the migration of legacy health data into MHS GENESIS, leading a team to ensure seamless integration and data quality. Collaborate with stakeholders to define architecture and standards, driv...
1 week ago
$135K - $155K *
Drive impactful data solutions by bridging business needs with engineering teams. Own project intake, prioritize requests, and ensure clear communication across departments to enhance efficiency and d...
1 week ago
$115K - $120K *
Elevate software quality by managing test planning, execution, and reporting. Collaborate with development teams, mentor junior testers, and ensure compliance with cybersecurity standards while drivin...
1 week ago
$110K - $135K *
Join a dynamic team to oversee tax engagements, manage client relationships, and mentor junior staff. Utilize your expertise in tax planning and compliance while contributing to various consulting pro...
1 week ago
$125K - $133K *
Champion the development of Generative AI solutions, leading an agile team to enhance products and tooling. Drive AI adoption, mentor engineers, and ensure best practices while collaborating across de...
1 week ago
Software Engineer - Technology
$108K - $115K *
Unlock your potential as a full stack engineer, collaborating in an agile team to develop innovative applications and features, while leveraging cutting-edge AI technologies to enhance product offerin...
1 week ago
$110K - $130K *
Transform your career by guiding strategic growth through identifying and capturing high-value opportunities in the Federal market. Leverage relationships and insights to execute comprehensive capture...
Reposted 1 week ago
Data Engineer | VA Claims Modernization
$120K - $180K *
Drive the modernization of Veterans Benefits Administration claims processing by designing and optimizing scalable data pipelines and solutions, ensuring efficient data integration and analytics for i...
1 week ago
$102K - $174K *
Engage with us to lead Agile delivery across multiple Scrum teams, enhancing collaboration and efficiency. Drive continuous improvement, facilitate key ceremonies, and ensure alignment with project go...
1 week ago
UI/UX Designer - Clearance Required
$102K - $174K *
Join a team that's redefining user experiences in Robotics and Autonomous Systems. As a UI/UX Designer, you'll create intuitive interfaces, conduct user research, and collaborate with developers to de...
1 week ago
Regional Business Director, Greatlakes
$230K - $260K *
Oversee regional sales strategies and lead a team to drive oncology product sales. Collaborate cross-functionally to enhance market insights and ensure compliance while fostering team development and...
1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.