Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $111,580
$99K - $166K *
Join a dynamic team to manage supplier agreements, ensuring compliance and efficiency in contract administration. Drive governance processes, facilitate stakeholder collaboration, and enhance contract...
1 week ago
Senior Solution Engineer (Agriculture SaaS)
$93K - $123K *
Engage with enterprise customers to drive complex sales opportunities, leveraging technical expertise and industry knowledge to deliver tailored solutions and compelling presentations that demonstrate...
1 week ago
$175K - $210K *
Shape the future of corporate law by providing strategic legal counsel on M&A, governance, and compliance for a dynamic multinational company. Collaborate with diverse teams to navigate complex transa...
1 week ago
Licensed Clinical Social Worker - Primary Care Behavioral Health w/bonus - 5401
$83K - $93K *
Transform patient care by leveraging your expertise as a Licensed Clinical Social Worker. Collaborate with interdisciplinary teams to assess and implement treatment plans, enhancing the psychosocial w...
1 week ago
$105K *
Lead the charge in driving new business sales across K-12 districts, building impactful partnerships and advocating for early literacy solutions. Collaborate with internal teams to maximize outreach a...
1 week ago
Cybersecurity Regional Manager
$134K - $241K *
Elevate your career by leading cybersecurity initiatives across California and the West Coast. Drive customer engagement, enhance security compliance, and support critical infrastructure sectors while...
1 week ago
Senior Marketing Campaigns Manager
$145K - $185K *
Transform account-based marketing strategies into impactful campaigns that drive pipeline growth and revenue. Lead integrated initiatives across multiple channels, ensuring alignment with sales and ma...
Reposted 1 week ago
Director, QMS Process Owner - Global Change Control Management
$168K - $228K *
Transform global GxP Change Management processes by leading strategy, governance, and continuous improvement initiatives across the product lifecycle, ensuring effective risk-based changes and collabo...
1 week ago
Associate Director, Global Commercial Trade Compliance
$138K - $188K *
Lead global trade compliance initiatives, ensuring adherence to regulations across multiple jurisdictions. Drive strategic programs for import/export operations, risk management, and partner governanc...
1 week ago
$110K - $130K *
Engineer critical electrical and mechanical systems for data centers, leading field support, troubleshooting, and reliability improvements while developing operational standards and mentoring teams to...
1 week ago
HSE and Portfolio Performance Lead
$110K - $130K *
Lead the charge in enhancing health, safety, and environmental performance across data center construction projects. Collaborate with teams to ensure compliance with OSHA standards and drive continuou...
1 week ago
$110K - $130K *
Innovate in cancer research by designing and deploying advanced AI and machine learning solutions. Collaborate with cross-functional teams to develop multimodal models integrating diverse clinical dat...
1 week ago
Senior Product Marketing Manager (US)
$120K - $145K *
Unlock potential by leading product marketing strategies for developer-facing solutions. Collaborate across teams to enhance messaging, drive customer engagement, and ensure successful deployments, al...
1 week ago
$95K - $125K *
Transform client relations through innovative sales strategies while achieving consistent targets in a dynamic market. Drive growth by effectively managing existing partnerships and exploring new oppo...
Reposted 1 week ago
Salesforce Solutions Architect (Financial Services Cloud) - USA (Remote)
$120K - $145K *
Shape innovative Salesforce solutions for financial services by leading design, architecture, and delivery of complex projects. Collaborate with clients and teams to ensure successful implementations...
1 week ago
Colleague Finance Functional Consultant - Remote (anywhere in US)
$90K - $110K *
Partner with us to enhance financial systems in higher education. Leverage your Colleague Finance expertise to optimize processes, troubleshoot issues, and support institutions in their technology tra...
1 week ago
Senior/Principal Software Engineer
$150K - $180K *
Develop and optimize high-performance software systems using Rust, focusing on Linux environments and distributed applications. Collaborate on architecture and enhance software quality through modern...
1 week ago
Solutions Engineer | PST or EST US | Remote
$182K - $226K *
Unlock potential by joining a dynamic team that drives customer success through technical expertise and innovative solutions, enhancing product engagement and collaboration in a fast-paced startup env...
1 week ago
Director, Application & Technical Service
$135K - $160K *
Drive a unified technical organization to enhance customer support from application discovery to project conversion, focusing on team development, technical selling, and improving customer experiences...
1 week ago
$125K - $172K *
Transform healthcare delivery by managing CDI operations, liaising with vendors, ensuring quality, and fostering staff development. Join a collaborative team to enhance patient care through innovative...
Reposted 1 week ago
$135K - $160K *
Lead the charge in offensive security research, tackling software supply chain vulnerabilities and zero-day threats. Collaborate with teams to innovate security capabilities and publish impactful find...
1 week ago
Associate Director, Biostatistics
$173K - $209K *
Transform your career by leading biostatistical strategies for clinical trials, driving innovative therapies from design to regulatory submission. Collaborate with multidisciplinary teams to ensure da...
1 week ago
$130K - $150K *
Join a dynamic team to design and develop innovative mobile solutions across Android and iOS. Take ownership of projects, collaborate with peers, and contribute to the broader tech stack while enhanci...
1 week ago
Director, Pricing Strategy and Monetization ( Remote)
$233K - $330K *
Elevate your career by leading innovative pricing strategies for cutting-edge AI solutions. Collaborate across teams to optimize monetization models and drive value in a dynamic market, ensuring Cisco...
1 week ago
Vice President, Sales - Integrated Solutions
$220K - $275K *
Accelerate growth by leading the demand engine for the Integrated Solutions SBU, driving bookings and revenue across Space and Aerospace & Defense markets while ensuring alignment with strategic goals...
1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.