Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $111,580
Field Reimbursement Manager OBL - Johnson & Johnson MedTech, Circulatory Restoration
$134K - $231K *
Unlock potential by driving strategic reimbursement initiatives to enhance patient access and market presence for innovative medical products. Collaborate with diverse stakeholders to navigate coding...
1 week ago
Senior Manager Customer Repair
$129K - $172K *
Transform critical customer service challenges into strategic solutions by leading a high-performing team focused on executive escalations, automation, and continuous improvement initiatives that enha...
1 week ago
Senior Marketing Platform Administrator- Salesforce
$95K - $115K *
Pioneer impactful marketing solutions by mastering platform administration, driving key integrations, and enabling agile collaboration with cross-functional teams to enhance engagement strategies and...
Reposted 1 week ago
Customer Success Manager (Technical)
$80K - $95K *
Lead the charge in customer success by ensuring seamless integration and support for connected hardware, driving account growth through exceptional service and technical expertise...
1 week ago
$100K - $120K *
Transform the insurance appeals process by managing, researching, and drafting compliant responses to billing deductions. Collaborate with legal teams to enhance efficiency and build strong relationsh...
Reposted 1 week ago
$96K *
Take ownership of e-commerce platform administration and vendor operations, ensuring seamless integration and performance of SaaS tools. Collaborate cross-functionally to enhance direct-to-consumer ca...
1 week ago
Principal HL7 Integration Engineer
$110K - $140K *
Shape the future of healthcare integration by leading and executing complex HL7 projects. Utilize your expertise in medical informatics and enhancing customer satisfaction while managing dynamic, mult...
Reposted 1 week ago
Modular Sales Representative - Virginia (Remote)
$80K - $95K *
Join a team that's driving growth in modular sales by managing complex rental and sales opportunities. Leverage your consultative sales skills to build strategic relationships and achieve revenue goal...
1 week ago
$150K - $200K *
Elevate your career by leading HCP engagement and clinical marketing initiatives. Drive strategic insights and educational content for the HSCT portfolio, fostering impactful connections and enhancing...
1 week ago
$80K - $95K *
Drive client success by managing a portfolio of accounts, optimizing Meta campaigns, and fostering strong relationships. Lead strategy discussions, analyze performance data, and ensure client satisfac...
1 week ago
Financial Services Marketing Manager
$80K - $95K *
Unlock your potential by managing client relationships and Meta campaigns. Drive performance, optimize strategies, and ensure client satisfaction while leading multiple accounts in a dynamic, hands-on...
1 week ago
$125K - $150K *
Transform enterprise data architecture through expert Azure platform engineering, enhancing reliability, governance, and cost-efficiency while collaborating with cross-functional teams to optimize dat...
Reposted 1 week ago
Sales Senior Manager - Commercial Sales
$140K - $160K *
Champion the future of commercial sales by leading strategy, driving growth, and fostering key customer relationships. Collaborate cross-functionally to achieve sales targets and enhance market share...
1 week ago
Quality Assurance Senior Manager
$132K - $178K *
Optimize supplier quality oversight by leading cross-functional teams, ensuring compliance with global standards, and driving continuous improvement initiatives to enhance performance and mitigate ris...
1 week ago
$88K - $118K *
Join us to analyze and document business and technical requirements, implement process improvements, and support ERP projects. Collaborate with teams to ensure accurate reporting and optimize system s...
1 week ago
Senior Director, Contact Center
$150K - $180K *
Lead the future of patient experience by driving strategic initiatives and operational excellence in a high-volume healthcare contact center. Collaborate with cross-functional teams to enhance service...
Reposted 1 week ago
Manager of Strategy & Corporate Development
$115K - $171K *
Champion strategic growth by leading analyses that drive international expansion and acquisitions. Collaborate with senior leaders to shape decisions and deploy AI agents for enhanced efficiency in a...
Reposted 1 week ago
Senior Manager, Data Engineering
$135K - $160K *
Lead the charge in transforming data accessibility for product teams and AI agents. Oversee a team of data engineers to build a robust platform that ensures secure, reliable data usage across the orga...
1 week ago
Senior Customer Success Manager, Strategic Accounts
$114K - $183K *
Drive customer success by managing strategic accounts, fostering partnerships, and enhancing product adoption. Collaborate with executives to ensure satisfaction and deliver actionable insights for co...
1 week ago
Client Success Executive - Prescription Benefits
$80K - $95K *
Drive client success by leading strategic account teams, ensuring satisfaction, and fostering strong relationships. Leverage expertise to enhance service delivery and support client retention through...
Reposted 1 week ago
Clinical Operations Manager-F- budgets and contracts - FSP
$110K - $130K *
Drive clinical operations excellence by managing protocol compliance, delivering budget oversight, and ensuring successful study start-up in alignment with regulatory standards and internal policies w...
Reposted 1 week ago
$166K - $309K *
Lead the charge in managing contract performance for mission-critical operations, ensuring compliance with service level indicators and overseeing resource allocation. Drive strategic initiatives and...
1 week ago
$100K - $120K *
Empower our provider team's mission by designing innovative tools for therapists. You'll create streamlined solutions that enhance patient care, drive efficiency, and leverage technology while collabo...
Reposted 1 week ago
Vice President, Revenue Integrity - DRG & DRGV (REMOTE)
$150K - $180K *
Drive your career with a leadership role focused on Revenue Integrity, overseeing strategic direction, performance metrics, and team development to enhance operational efficiency and client satisfacti...
1 week ago
$125K *
Join our dynamic sales team to drive net-new logo sales in the mid-market and enterprise sectors. Leverage your HRMS/Payroll expertise to exceed quotas and deliver exceptional solutions, supported by...
1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.