Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $111,580
$100K - $120K *
Champion growth by owning the full sales cycle, educating clients, and driving custom part sourcing for hardware companies. Collaborate with a remote team to deliver exceptional service and build last...
1 week ago
$170K - $200K *
Transform customer experiences by providing technical expertise and solutions. Collaborate with sales and engineering teams to deliver impactful product demonstrations and address technical challenges...
1 week ago
Clinical Trial Manager/Senior Clinical Trial Manager
$110K - $200K *
Join a team that's dedicated to advancing clinical research by leading operational aspects of trials, ensuring compliance with protocols and regulations, and fostering collaboration among stakeholders...
1 week ago
Sr Manager, Payroll Connection & Integration Support
$135K - $145K *
Lead the charge in optimizing payroll integration operations, managing teams, and driving strategic alignment across functions. Elevate customer experience through data-driven insights and innovative...
1 week ago
Sr. Software Engineer - Stacklok Enterprise
$189K - $231K *
Innovate and shape the future of AI platforms as a Senior Engineer, designing and building critical subsystems for enterprise Kubernetes environments. Collaborate with customers and mentor engineers t...
1 week ago
Director, Market Access - Commercial Coverage & Reimbursement
$187K - $281K *
Redefine market access strategies by leading payer engagement to enhance patient access to genomic testing. Collaborate cross-functionally to drive favorable coverage and reimbursement policies, ensur...
1 week ago
Senior Field Engineer, Data Center Design and Engineering
$320K - $405K *
Transform the future of data center engineering by resolving on-site technical issues, collaborating with contractors, and ensuring project success through effective problem-solving and communication...
1 week ago
$130K - $160K *
Create impactful solutions as a Senior Product Engineer, owning projects from concept to delivery. Collaborate with a dynamic team, leveraging AI tools to enhance development while mentoring peers and...
1 week ago
Software Engineer 4/5 - Data and Feature Infrastructure, AI Platform
$466K - $500K+*
Elevate your career by building a cutting-edge ML data platform that enhances productivity for ML practitioners. Collaborate with experts to create innovative solutions for feature computation and sha...
Reposted 1 week ago
Senior Product Manager - Fraud
$200K - $250K *
Champion the evolution of fraud prevention strategies, enhancing customer experience while safeguarding against risks. Collaborate cross-functionally to design innovative solutions that balance securi...
1 week ago
Dealer Development Manager (Portland, OR)
$80K - $95K *
Join a dynamic team as you develop and maintain dealer partnerships, driving growth and enhancing customer satisfaction in the auto finance sector. Leverage your expertise to navigate market trends an...
1 week ago
$95K - $160K *
Elevate your career by supporting senior leaders in a dynamic tech environment. Manage complex calendars, coordinate travel, and streamline processes to enhance productivity and drive success across g...
1 week ago
$100K - $120K *
Unlock potential by leading a dynamic SQA team to enhance software quality. Drive testing strategies, mentor team members, and ensure compliance with best practices while managing multiple projects in...
1 week ago
$110K - $125K *
Analyze customer needs and drive product initiatives using AI tools. Own features from discovery to delivery, ensuring alignment with business priorities and quality outcomes while collaborating acros...
1 week ago
Director, Consulting & Advisory Alliances, North America
$150K - $170K *
Join a team that's expanding strategic partnerships with consulting firms to enhance supply chain solutions. Drive growth through collaboration, relationship management, and innovative go-to-market st...
1 week ago
$210K - $230K *
Drive your career with a dynamic role focused on enterprise B2B sales, where you'll cultivate relationships, leverage data insights, and collaborate cross-functionally to close high-value deals in a f...
1 week ago
$122K - $205K *
Drive measurable SEO results by owning key surfaces and experiments, leveraging AI tools for hands-on building, and collaborating across teams to enhance organic growth and visibility in a dynamic, re...
1 week ago
$141K - $196K *
Unlock potential by developing causal machine-learning models to optimize customer offers, analyzing complex data, and translating findings into actionable strategies for enhanced conversion rates acr...
1 week ago
$168K - $232K *
Lead the charge in executing innovative financing strategies for our AI lending marketplace. Collaborate with investors and stakeholders to drive structured transactions, ensuring scalable funding sol...
1 week ago
$78K - $85K *
Build your career in outpatient orthopedic physical therapy, focusing on patient care while enjoying competitive pay, mentorship, and growth opportunities in a supportive environment...
1 week ago
$120K - $145K *
Unlock potential by leading strategic partnerships and driving growth initiatives. Collaborate cross-functionally to enhance business opportunities and ensure partner success through data-driven insig...
1 week ago
$140K - $160K *
Lead strategic life sciences accounts, driving growth and team development while ensuring project success and client satisfaction through strong relationships and innovative solutions...
1 week ago
$85K - $124K *
Drive impactful SAP projects as a Project Manager/Scrum Master, leading teams to deliver innovative solutions. Collaborate with stakeholders, manage product backlogs, and ensure agile practices to mee...
1 week ago
Field Installation Project Manager
$84K - $120K *
Lead the charge in coordinating installations of advanced imaging solutions, ensuring seamless communication and execution throughout the pre-installation and installation phases to enhance customer s...
1 week ago
$250K - $300K *
Join a dynamic team as you drive enterprise sales across mid-market to Fortune 500 accounts. Own the entire sales cycle, engage multi-stakeholder buying committees, and leverage AI tools to redefine b...
1 week ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.