Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,974
Channel Systems (Sales) Engineer
$225K - $280K *
Engage as a key technical resource for channel sales, driving success with global partners. Leverage your expertise in networking solutions to enhance relationships, deliver impactful demos, and suppo...
5 days ago
Spotfire Sales Executive - Energy
$110K - $130K *
Drive growth by managing end-to-end sales cycles in the Energy sector, enhancing customer relationships, and executing strategies to exceed targets while collaborating with cross-functional teams for...
5 days ago
$68K - $105K *
Help us lead enterprise-wide incident responses and internal investigations into misconduct, ensuring compliance and effective fraud detection while collaborating across departments to uphold organiza...
Reposted 5 days ago
Lead Technical Implementation Analyst
$120K - $150K *
Transform the delivery landscape by leading cross-functional initiatives, mentoring analysts, and driving strategic solutions across business units and external partners. Engage deeply in project exec...
5 days ago
$83K - $104K *
Lead the charge in managing complex client programs, driving operational excellence and strategic direction while fostering strong stakeholder relationships and ensuring exceptional service delivery...
5 days ago
Staff Software Engineer, AI Systems
$188K - $265K *
Accelerate progress at the forefront of AI infrastructure by leading technical direction, ensuring platform architecture meets company ambitions, and fostering collaboration across engineering teams f...
Reposted 5 days ago
Manager, Business Quality - Meals & Beverages
$113K - $155K *
Champion quality excellence by executing business programs across manufacturing sites, collaborating with cross-functional teams to enhance product standards, manage consumer insights, and drive conti...
5 days ago
VP, Product Marketing - Identity Security Portfolio
$180K - $220K *
Lead the charge in transforming identity security marketing strategies, driving growth and market leadership. Oversee a dynamic team to enhance product positioning, execute go-to-market plans, and sha...
5 days ago
Project Safety Manager - Data Center
$95K - $125K *
Transform safety culture by leading project teams in compliance and incident prevention. Develop safety plans, conduct audits, and facilitate training to ensure a safe work environment on large constr...
5 days ago
Senior Power Systems Engineer, IBR Modeling, PSS/E and PSCAD
$130K - $157K *
Engineer innovative power system models and analyses to optimize utility-scale solar and storage solutions, working collaboratively with global teams to ensure compliance and advance SMA's technical c...
Reposted 5 days ago
Senior Manager, Global Procurement (Soft Home - Bedding)
$164K - $240K *
Lead global procurement initiatives, optimizing sourcing strategies and cost structures to ensure high-quality products at competitive prices, while enhancing supply chain efficiencies and aligning wi...
Reposted 5 days ago
Manager, Return To Vendor (RTV)
$124K - $138K *
Shape the future of vendor relations by managing the RTV process, negotiating effectively, and collaborating cross-functionally to maximize recovery value and streamline operations within the supply c...
Reposted 5 days ago
Senior Manager, Global Procurement (Bags and Accessories)
$164K - $240K *
Lead strategic procurement initiatives to achieve optimal cost structures and maintain supply continuity. Collaborate across teams to drive innovation in sourcing and enhance quality standards while a...
Reposted 5 days ago
$80K - $95K *
Champion cross-functional projects to enhance operational efficiency and achieve organizational goals. Lead initiatives from planning to completion, ensuring timely delivery within scope and budget wh...
5 days ago
Senior Director - AI Enablement
$180K - $200K *
Drive the future of AI capability by leading the development of role-specific tools and workflows, ensuring measurable impact and adoption across teams. Collaborate with HR to enhance learning and ope...
5 days ago
Director Security Infrastructure & Engineering
$138K - $200K *
Drive the strategic direction of enterprise security infrastructure, leading teams to design, implement, and optimize security solutions across on-premises, cloud, and hybrid environments while ensuri...
5 days ago
Senior Partner AI Enablement Manager
$125K - $150K *
Accelerate progress at building a world-class AI Receptionist partner ecosystem, driving revenue and customer success through strategic enablement programs. Collaborate cross-functionally to enhance p...
5 days ago
Customer Success Manager, Enterprise
$92K - $139K *
Drive exceptional customer success by managing a complex portfolio of Enterprise accounts, enhancing software value through strategic relationships and problem-solving. Influence industry revenue and...
Reposted 5 days ago
Nurse Practitioner - Express Care Sumrall - Full Time
$90K - $110K *
Elevate patient care by diagnosing illnesses, prescribing treatments, and coordinating health plans. Collaborate with healthcare teams to ensure comprehensive patient assessments and promote health th...
5 days ago
$105K - $150K *
Transform your career by joining a dynamic team focused on enhancing security compliance for cloud services. Leverage your expertise in IT security to assess architectures, guide vendors, and ensure a...
5 days ago
Senior Principal - Business Consulting
$210K - $256K *
Unlock potential by leading strategic payment modernization efforts, managing client relationships, and delivering complex digital solutions while collaborating across teams to enhance operational eff...
Reposted 5 days ago
$73K - $102K *
Join a dynamic team to enhance software solutions through coding, testing, and collaboration. Contribute to design discussions, maintain code quality, and ensure seamless transitions to new applicatio...
5 days ago
$100K - $120K *
Join a team that's dedicated to enhancing patient care through empathetic pharmacy consulting, medication management, and operational excellence. Lead pharmacy staff, ensure compliance, and improve pa...
5 days ago
$100K - $120K *
Empower patients through expert pharmacy consulting and clinical services. Manage pharmacy operations, enhance patient experiences, and lead staff development while ensuring compliance with regulation...
5 days ago
Senior Systems & Security Engineer
$110K - $130K *
Empower our IT environment by enhancing security and reliability through hands-on systems engineering, cybersecurity, and incident response. Collaborate across teams to design, implement, and manage s...
5 days ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.