Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Jobs in Mississippi

Average Salary in USD

Average Salary: $110,974

Sort By: Relevance

$80K - $95K *

Engage with clients to enhance their cybersecurity resilience by leading incident response efforts, providing expert guidance, and preparing detailed reports to mitigate risks and improve security pos...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$155K - $185K *

Partner with us to lead high-impact projects in healthcare marketing, managing budgets and teams while ensuring creative excellence and strategic alignment. Drive client success through collaboration...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $246K *

Champion innovative IAM solutions by designing secure software and optimizing SaaS services. Collaborate across teams to embed security practices, conduct threat modeling, and enhance monitoring syste...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Lead operations as you manage production, engineering, quality, and sales teams. Drive continuous improvement and ensure safety while fostering a culture of teamwork and accountability to deliver supe...

Reposted 4 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$75K - $94K *

Shape exceptional client experiences by leading AV production and design projects. Collaborate across sectors to ensure successful event execution while building lasting relationships and maintaining...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$120K - $145K *

Lead the development of AI-driven document extraction solutions, ensuring accuracy and efficiency. Collaborate with cross-functional teams to prioritize features and manage product roadmaps, driving i...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$193K - $238K *

Unlock potential by driving enterprise sales strategies to acquire new clients. Engage with C-level executives, manage key accounts, and exceed revenue goals while advocating for innovative EHS soluti...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$466K - $500K+*

Join a team that's shaping the future of AI by designing and building scalable platforms for large-scale machine learning model training, enhancing performance, and creating user-friendly experiences...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$190K - $250K *

Analyze and evaluate therapeutic opportunities to drive innovation and business development. Collaborate with interdisciplinary teams to assess scientific and commercial viability, ensuring alignment...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Lead the charge in enhancing organizational security by developing security frameworks, assessing controls, and collaborating with technical teams to create a resilient security architecture for moder...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $160K *

Champion the evolution of Workday PSA by architecting scalable solutions that integrate finance and operations. Lead major initiatives from design to implementation, ensuring alignment with global sta...

RemoteRemote

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Transform customer HR environments by implementing and optimizing AI solutions. Collaborate with clients to configure integrations, troubleshoot issues, and enhance workflows, ensuring seamless deploy...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$185K - $315K *

Join us to shape strategic financial planning and analysis, leveraging AI to enhance forecasting and decision-making. This high-impact role collaborates with executives, driving insights that align wi...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Consumer Technology

$85K - $124K *

Champion innovative project management solutions, guiding teams through configuration, product demonstrations, and stakeholder collaboration to deliver value-driven consulting services that adapt to e...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $150K *

Take ownership of SSP partnerships to optimize programmatic supply, enhance monetization, and ensure compliance. Collaborate with cross-functional teams to drive revenue growth and improve inventory q...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Media

$70K - $110K *

Champion the resolution of complex Tier 3 auto claims, leveraging expertise in investigation, liability assessment, and negotiation to ensure effective outcomes while serving as the primary contact fo...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$200K *

Transform the landscape of life sciences partnerships by driving co-developed deals. Leverage your extensive network and expertise to source, pitch, and close high-value agreements that enhance patien...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Healthcare

$150K - $180K *

Advance healthcare solutions by building executive relationships and driving enterprise sales. Lead the sales lifecycle, develop strategic accounts, and leverage modern tools to optimize revenue growt...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Elevate your career by leading the strategic growth of our Attorney Banking Division. Drive business development, mentor a remote team, and enhance client experiences while achieving personal producti...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $135K *

Shape client relationships and drive growth by expanding existing accounts, identifying service opportunities, and delivering tailored managed security solutions that enhance compliance and risk manag...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$222K - $278K *

Join a dynamic team to drive enterprise sales, transforming industries through innovative technology. Engage with C-level executives, manage complex deals, and build lasting relationships that impact...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$175K - $200K *

Lead the innovation and implementation of cutting-edge technology solutions to enhance data governance, optimize operations, and improve workplace experiences while managing a high-performing team of...

United StatesRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$160K - $180K *

Lead the charge in transforming our payment gateway strategy, driving performance and innovation. Collaborate with cross-functional teams to enhance user experience and ensure compliance while optimiz...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$101K - $132K *

Drive impactful media relations and communications strategies to enhance advocacy efforts for Healthy Communities. Collaborate with diverse teams to shape narratives, engage with journalists, and expa...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$120K - $145K *

Elevate your career by leading the development of high-quality clinical documents for global regulatory submissions. Collaborate with cross-functional teams to ensure data-driven messaging aligns with...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.