Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,902

Sort By: Relevance

$176K - $208K *

Shape the future of compliance by leading risk-based monitoring, auditing, and investigations. Drive strategic initiatives, enhance governance processes, and collaborate with stakeholders to ensure ef...

Reposted yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$248K - $299K *

Shape the future of drug safety by leading global risk management efforts, conducting comprehensive safety evaluations, and ensuring regulatory compliance while collaborating with cross-functional tea...

Reposted yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$167K - $191K *

Unlock potential by leading HEOR/RWE initiatives, collaborating with cross-functional teams to drive evidence generation and strategic insights that inform clinical practice and access in oncology, en...

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$164K - $204K *

Shape the future of clinical development by providing critical statistical support across multiple projects. Collaborate with cross-functional teams to ensure regulatory compliance and scientific inte...

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Shape the future of client solutions by leading technical discovery and crafting innovative data-driven strategies. Collaborate with sales teams to drive success and ensure seamless implementation of...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Technical Services

$95K - $115K *

Champion builder demand and drive revenue growth in the New England region. Leverage strong market insights and customer relationships to convert opportunities and enhance channel activation, ensuring...

Reposted yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Champion the deployment of cutting-edge AI systems in diverse environments. Collaborate with teams to ensure seamless installation and operation of hardware and software, while providing exceptional c...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$168K - $195K *

Lead strategic engineering initiatives in a factory setting, ensuring safety, compliance, and sustainability while driving operational excellence and collaboration across teams to achieve long-term go...

Yesterday

  •   8 - 10 years exp.  •   Food & Beverages

$115K - $125K *

Join our dynamic team to oversee and elevate a 24/7 distribution operation, driving excellence and efficiency while leading a large management and hourly workforce to achieve outstanding results and c...

Reposted yesterday

  •   5 - 7 years exp.  •   Hospitality & Recreation

$115K - $125K *

Manage culinary operations and lead a team of chefs, ensuring high food quality and adherence to standards. Deliver exceptional culinary solutions while maintaining client relationships and optimizing...

Reposted yesterday

  •   Less than 5 years exp.  •   Hospitality & Recreation

$140K - $145K *

Champion exceptional hospitality experiences by leading premium services operations, driving revenue growth, and enhancing guest satisfaction across various venues and events. Collaborate with teams t...

Reposted yesterday

  •   5 - 7 years exp.  •   Hospitality & Recreation

$135K - $150K *

Drive M&A integration efforts by managing cross-functional projects, developing strategies, and collaborating with leadership to enhance growth in healthcare services. Lead due diligence and create fo...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$85K - $120K *

Lead the charge in optimizing CNC manufacturing processes, developing strategies for additive and precision machining, and ensuring high-quality production while driving continuous improvement initiat...

Reposted yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$242K - $290K *

Empower strategic partnerships by managing alliances, driving collaboration, and ensuring alignment with organizational goals. Leverage your expertise to foster trust and deliver impactful outcomes in...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Empower financial operations by developing budgets, analyzing spending, and driving decision-making processes. Collaborate with cross-functional teams to enhance reporting and support a fast-paced, in...

Reposted yesterday

  •   8 - 10 years exp.  •   Energy & Utilities

$162K - $271K *

Unlock potential by leading complex substation designs and project coordination. Utilize your electrical engineering expertise to develop critical design deliverables, manage budgets, and mentor junio...

Reposted yesterday

  •   11 - 15 years exp.  •   Real Estate & Construction

$110K - $160K *

Optimize customer networks while delivering integrated networking and cybersecurity solutions. Collaborate globally, enhance performance, and ensure satisfaction as you tackle complex challenges in an...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$204K - $348K *

Elevate model serving capabilities by leading a high-performing team to optimize inference APIs, ensuring reliability and efficiency in production environments while balancing technical and strategic...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$138K - $202K *

Drive impactful strategies in enterprise advertising sales, partnering with complex clients to leverage AI and predictive insights for revenue growth. Influence outcomes in a fast-paced environment wh...

United StatesRemote

Reposted yesterday

  •   11 - 15 years exp.  •   Information Technology

$150K - $500K *

Champion exceptional dental care by leading clinical diagnosis and treatment, fostering a patient-centric environment, and collaborating with diverse teams to enhance practice operations and patient e...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Lead the monthly close and day-to-day accounting operations, ensuring accuracy and efficiency as the business scales. Collaborate with cross-functional teams to enhance processes and implement automat...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$104K - $120K *

Transform patient care by delivering exceptional dental hygiene services. Collaborate with a dedicated team in a modern practice, ensuring quality treatment and fostering patient trust while enhancing...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$85K - $106K *

Empower clients by leading innovative paid search strategies across diverse categories. Collaborate with cross-functional teams to drive performance, optimize campaigns, and connect search tactics to...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$115K - $150K *

Champion global post-market activities for medical devices, leading complaint handling, vigilance, post-market surveillance, and data analysis. Collaborate with cross-functional teams to ensure compli...

Massachusetts, USRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Healthcare

$198K - $318K *

Serve as the lead legal advisor on U.S. labor and employment matters, providing strategic, risk-based guidance while partnering with HR and leadership across a multi-state, distributed workforce to en...

Reposted yesterday

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.