Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,901

Sort By: Relevance

$160K - $200K *

Lead the charge in delivering complex digital quality services for enterprise clients. Oversee testing programs, manage cross-functional teams, and ensure alignment with business outcomes while foster...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Information Technology

$120K - $145K *

Accelerate progress at the forefront of pricing strategy and operations. Lead cross-functional teams to innovate pricing models, enhance profitability, and drive market competitiveness while managing...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Lead the charge in defining technical solutions, managing risks, and guiding development teams to ensure optimal software delivery while collaborating with clients and enforcing coding standards...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Enterprise Technology

$240K - $300K *

Lead the charge in advancing Maternal-Fetal Medicine across a multi-site health system, ensuring high-quality, equitable care while fostering academic excellence and collaborative practices among dive...

Today

  •   5 - 7 years exp.  •   Healthcare

$120K - $160K *

Empower our Managed Services tooling ecosystem by designing integrations and automations. You'll lead the configuration of Jira Service Management, optimize alerting, and ensure seamless connectivity...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$125K - $150K *

Drive new business opportunities by cultivating relationships and managing the full sales cycle. Collaborate with teams to enhance messaging and exceed quotas while ensuring a positive customer experi...

Today

  •   5 - 7 years exp.  •   Information Technology

$235K - $270K *

Transform the landscape of oncology sales by driving growth within your territory. Collaborate with sales teams to identify opportunities, engage with key accounts, and promote cutting-edge diagnostic...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$124K - $157K *

Elevate patient care by supporting pharmacy operations across multiple locations, ensuring safe dispensing, and fostering a culture of excellence. Collaborate with teams to enhance patient experiences...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead the charge in optimizing Agile practices for cross-functional teams, ensuring effective prioritization and communication. Protect team capacity while mentoring Scrum Masters to enhance execution...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Finance & Insurance

$77K - $202K *

Lead enterprise risk management initiatives by evaluating governance and internal controls. Collaborate with clients to enhance control environments, mentor junior staff, and adapt to evolving needs w...

Today

  •   Less than 5 years exp.  •   Legal & Accounting

$244K - $295K *

Champion Precision Medicine initiatives by leading diagnostic development and validation efforts. Collaborate across teams to align strategies, enhance patient selection, and drive commercial success...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$140K - $180K *

Elevate customer insights by translating data into actionable product capabilities. Collaborate with cross-functional teams to prioritize initiatives, enhance marketing performance, and leverage AI fo...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Real Estate & Construction

$200K - $250K *

Join a pioneering initiative to revolutionize drug discovery, leading the charge as a Co-founder & CEO. Drive strategic partnerships, oversee fundraising, and build a robust commercial engine while fo...

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$168K - $240K *

Lead the charge in optimizing business operations through innovative solutions, driving efficiency and productivity while fostering cross-functional collaboration and data-driven decision-making to en...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Information Technology

$235K - $300K *

Empower primary care excellence by leading clinical and administrative teams, enhancing patient safety, and fostering provider development. Collaborate across specialties to ensure high-quality, acces...

Today

  •   Less than 5 years exp.  •   Healthcare

$224K - $336K *

Transform the future of Digital Power by leading strategic accounts and driving growth in a dynamic commercial organization. Collaborate across teams to enhance market strategies and ensure success in...

Today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Join a team that's dedicated to shaping corporate culture and driving HR strategies. Lead initiatives that align with core values, enhance employee engagement, and ensure compliance while fostering a...

Today

  •   Less than 5 years exp.  •   Technical Services

$224K - $336K *

Lead strategic growth in Digital Power accounts by driving sales strategies, managing a diverse team, and engaging with key stakeholders to enhance market presence and operational efficiency across mu...

Today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Engineer robust security solutions by assessing web applications and APIs. Leverage your expertise in OWASP and SANS frameworks to identify vulnerabilities, conduct thorough testing, and enhance secur...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$100K - $120K *

Unlock potential by partnering with ABA practice owners to enhance operations, drive growth, and improve performance. Collaborate closely with providers to navigate challenges and implement strategic...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$85K - $105K *

Join us to analyze and adjudicate complex workers compensation claims, delivering innovative solutions in a dynamic environment. Collaborate with clients across industries while enjoying professional...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$135K - $165K *

Optimize Oracle Fusion SCM applications to elevate supply chain efficiency. Collaborate with cross-functional teams, providing expert support and ensuring alignment with business goals. Lead system co...

Reposted today

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Drive product strategy and execution for a critical portfolio area, leading cross-functional teams to transform user insights into impactful software solutions while mentoring others and shaping platf...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Consumer Technology

$110K - $130K *

Lead the charge in shaping product marketing strategies that drive adoption and pipeline. Collaborate with cross-functional teams to craft compelling narratives and ensure our differentiated value res...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Energy & Utilities

$130K - $140K *

Elevate your career by joining a dynamic team to design and implement innovative cloud solutions in a multi-cloud environment, ensuring scalability, security, and alignment with business objectives wh...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.