Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,888

Sort By: Relevance

$158K - $253K *

Oversee and enhance lab operations, ensuring reliability and safety while supporting engineering teams. Foster collaboration, optimize workflows, and implement best practices to drive innovation and e...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$192K - $307K *

Transform digital design by leading complex ASIC development, collaborating with cross-functional teams to define architecture and drive projects from inception to silicon. Enjoy ownership of critical...

Reposted 3 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$192K - $307K *

Join us to design and develop advanced mixed-signal ASICs, collaborating with various engineering teams to drive successful architectures and influence cutting-edge semiconductor test systems...

Reposted 3 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$80K - $111K *

Partner with us to transform patient care in advanced cochlear implant solutions. Build trusted relationships, execute strategic plans, and improve outcomes by leveraging clinical expertise and consul...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$177K - $278K *

Shape the future of GI oncology by leading strategic marketing initiatives, conducting opportunity assessments, and collaborating with cross-functional teams to drive commercial success in a fast-pace...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$212K - $333K *

Shape the future of small molecule development by leading analytical strategies, mentoring teams, and optimizing processes to accelerate drug candidates from concept to market while ensuring complianc...

3 days ago

  •   15+ years exp.  •   Pharmaceuticals & Biotech

$148K - $214K *

Innovate customer experience and automation solutions to streamline real estate closings. Drive strategy, prioritize product roadmaps, and collaborate across teams to enhance operational efficiency an...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$68K - $92K *

Manage high-level administrative support for R&D leaders, ensuring efficient operations and alignment with strategic priorities through effective calendar, travel, and budget management...

Reposted 3 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$127K - $133K *

Engineer scalable cloud platforms by automating processes and enhancing reliability. Collaborate with teams to streamline deployments and ensure secure, resilient infrastructure that meets evolving bu...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$184K - $225K *

Drive the future of patient support services by leading a dedicated team, ensuring high-quality case management, and enhancing patient experiences in the rare disease sector. Collaborate cross-functio...

Reposted 3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $112K *

Join a dynamic team to oversee servicing and repair operations, ensuring quality and safety standards are met while enhancing customer satisfaction and promoting employee development across various pr...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$122K - $171K *

Contribute to strategic marketing initiatives by leading product management efforts, enhancing market presence, and fostering relationships with healthcare professionals to drive business growth and a...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$140K - $160K *

Transform patient experiences by managing access to therapies in a dynamic team. Collaborate with healthcare providers and insurance companies to ensure seamless support for patients with rare disease...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Drive sales of service programs to exceed customer expectations and revenue goals. Collaborate with teams to manage leads, maintain customer relationships, and ensure effective service delivery while...

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$155K - $226K *

Champion innovative analytics strategies to enhance business insights, lead a skilled team of analysts and engineers, and drive efficiencies through advanced data solutions, empowering stakeholders ac...

Reposted 3 days ago

  •   11 - 15 years exp.  •   Telecommunications & Hardware

$98K - $141K *

Drive efficiency and reliability by leading a team of Controls Engineers to enhance regional plant technology and optimize machine processes, ensuring consistent implementation of industry standards a...

RemoteRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$165K - $215K *

Empower innovation in ophthalmic device development by leading global clinical strategies for surgical programs, from feasibility to regulatory submissions. Collaborate cross-functionally to drive pro...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$175K - $200K *

Champion strategic growth and account management with top-tier National Accounts. Lead a team towards innovative solutions, driving revenue and market impact while collaborating across departments for...

RemoteRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $90K *

Lead the charge in cultivating partnerships with Travel Advisors across the Northeast, driving business growth through relationship-building and strategic outreach in the European travel market...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$94K - $266K *

Empower customer success by designing and implementing AWS Connect solutions, conducting technology assessments, and leading project communications to enhance contact center operations and agent produ...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$92K *

Join a team that's dedicated to enhancing organ transplant processes by screening donor offers, managing communications, and ensuring compliance with OPTN guidelines while providing exceptional suppor...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$135K - $145K *

Join a team that's redefining healthcare advertising by leading art direction and design for HCP campaigns. Collaborate with creative partners to deliver compelling visual narratives while managing mu...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$135K - $145K *

Lead the charge in innovative healthcare advertising by directing art and design for HCP campaigns. Collaborate with creative teams to transform scientific information into impactful visuals, ensuring...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$140K - $205K *

Pioneer innovative Agentic AI solutions by leading cross-functional teams from concept to deployment. Collaborate with stakeholders to transform complex business needs into impactful, production-ready...

Reposted 3 days ago

  •   11 - 15 years exp.  •   Finance & Insurance

$100K - $135K *

Champion the development and support of integrations and automation solutions to enhance Unified Communications and enterprise platforms, driving operational efficiency and innovative customer experie...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.