Explore $100K+ Jobs in Massachusetts

Find professional opportunities in Massachusetts with salaries of $100,000 or more. From Boston and Cambridge to Worcester, Springfield, and other communities, the state offers a varied job market for experienced professionals seeking their next career move. Browse vetted listings on Ladders and explore roles aligned with your skills, experience, and compensation goals.

Discover Opportunities Across Massachusetts

Massachusetts is home to employers in industries including biotechnology, healthcare, finance, technology, higher education, consulting, and advanced manufacturing. Opportunities can range from specialized individual-contributor positions to director, vice president, and executive roles. Availability varies by employer and location, so review each listing for its requirements and work arrangement.

Find Roles That Match Your Experience

Use Ladders to explore high-paying professional jobs and focus your search by title, location, and area of expertise. Review responsibilities and qualifications carefully, then tailor your résumé to highlight relevant achievements, leadership experience, and measurable results.

Build Your Massachusetts Job Search

Whether you are targeting a role in Greater Boston or considering opportunities elsewhere in the state, a focused search can help you identify positions that fit your career priorities. Explore Massachusetts listings on Ladders to take the next step toward a role paying $100,000 or more.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,890

Sort By: Relevance

$130K - $160K *

Join a team that's dedicated to optimizing customer success through technical expertise. As a trusted advisor, you'll manage relationships, guide deployments, and ensure seamless adoption for federal...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Transform higher education through innovative Salesforce solutions, guiding institutions in architecture design, implementation, and best practices to enhance student engagement and operational effici...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Staffing

$86K - $129K *

Oversee and manage claims investigations, ensuring compliance with policies while leading a team to achieve optimal performance and cost management. Foster communication and training to align with bus...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$107K - $161K *

Join a team that's dedicated to managing complex Auto and General Liability claims. You'll handle high exposure cases, oversee litigation, and develop resolution strategies while collaborating with va...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$160K - $200K *

Drive strategic growth and operational excellence in cardiology, fostering physician partnerships and overseeing clinical and financial performance to enhance patient care and organizational success...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$114K - $134K *

Transform billing compliance by leading strategic initiatives, managing audits, and fostering education across teams. Drive adherence to regulations while overseeing a dedicated team to enhance operat...

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$130K - $150K *

Elevate laboratory operations by managing logistics, compliance, and safety in a dynamic research environment. Collaborate with scientists to streamline processes and ensure a well-functioning lab tha...

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$87K *

Lead the charge in maintaining and managing HVAC/Refrigeration systems across the Northeast, ensuring optimal performance and compliance while supervising technicians and overseeing inventory and vend...

Massachusetts, USRemote

Yesterday

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$83K - $133K *

Optimize customer interactions by managing order entry, tracking, and support activities across local business units and agent accounts, ensuring timely delivery and effective communication in a dynam...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$134K - $167K *

Lead the charge in designing and delivering enterprise-grade software solutions. Oversee technical teams, drive innovation, and ensure high-quality outcomes that align with business objectives while m...

Yesterday

  •   5 - 7 years exp.  •   Energy & Utilities

$175K - $210K *

Unlock potential by leading a transformative sales organization across diverse markets. Drive growth through strategic sales initiatives, team development, and robust forecasting, while transitioning...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$80K - $95K *

Champion student well-being by leading Counseling Services, overseeing clinical operations, and fostering collaboration to enhance mental health support for a diverse campus community...

Yesterday

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$190K - $230K *

Lead the accounting and financial reporting functions within a growing healthcare organization. Drive integrity across multiple entities, ensure compliance, and strategize cash management while suppor...

United StatesRemote

Reposted yesterday

  •   11 - 15 years exp.  •   Healthcare

$175K - $263K *

Lead the charge in developing bioanalytical strategies for oncology programs. Collaborate with cross-functional teams and stakeholders to ensure the success of bioanalytical assay design and implement...

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$92K - $110K *

Join a team that's dedicated to enhancing manufacturing processes for flight-critical hardware. Collaborate with operators and engineers to ensure quality and efficiency in sheet metal fabrication, we...

Yesterday

  •   Less than 5 years exp.  •   Aerospace & Defense

$107K - $143K *

Drive digital transformation by guiding lower-enterprise clients in leveraging data. Utilize solution selling to create tailored software solutions and manage complex sales cycles, collaborating cross...

Massachusetts, USRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Business Services

$134K - $223K *

Lead the charge in optimizing production operations for aircraft engines, driving safety, quality, and efficiency. Collaborate with a skilled team to implement continuous improvement strategies and ad...

Yesterday

  •   5 - 7 years exp.  •   Aerospace & Defense

$180K *

Champion the paid funnel strategy to drive capital into our real estate vertical. Own the entire process from ad creation to investor engagement, ensuring a seamless transition to the investor relatio...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Business Services

$110K - $130K *

Advance your career by leading the internal audit function, ensuring effective governance, risk management, and compliance. Drive strategic audit planning and execution while fostering a culture of in...

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$218K - $264K *

Drive innovative clinical trial designs and statistical analysis, collaborating with cross-functional teams to ensure regulatory compliance and quality deliverables while mentoring team members and co...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$350K - $425K *

Transform clinical development by leading strategic oncology trials, ensuring medical oversight and regulatory compliance while collaborating across teams to drive innovative drug strategies from earl...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Drive quality assurance initiatives by building automated test suites and collaborating with engineering teams to ensure performance, reliability, and security in a rapidly growing tech environment fo...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$182K - $291K *

Pioneer advanced electronic hardware development by leading architecture, driving technical decisions, and mentoring engineers. Shape the future of complex systems through innovative solutions and cro...

Yesterday

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$135K - $160K *

Lead the strategic design and management of comprehensive benefits programs, ensuring alignment with employee needs and company objectives. Drive innovation and compliance while enhancing employee eng...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$182K - $291K *

Champion innovation by leading the architecture and development of advanced electronic hardware systems. Leverage deep technical expertise and mentorship to drive critical decisions and enhance engine...

Yesterday

  •   8 - 10 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include experienced professional, management, director, vice president, and executive roles across fields such as technology, healthcare, biotechnology, finance, education, and manufacturing. Specific openings and requirements vary.

  • Where in Massachusetts can I find high-paying jobs?question toggle

    Opportunities may be available in Boston, Cambridge, Worcester, Springfield, and other parts of the state. Browse current listings and check each posting for its location and work arrangement.

  • How can I search for Massachusetts jobs paying $100,000 or more?question toggle

    Browse Massachusetts listings on Ladders and refine your search by job title, location, and expertise. Review each posting's compensation information and qualifications.

  • Are Massachusetts jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional job listings. Check the details of each listing to learn about the employer, role, location, compensation, and application requirements.