Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,890

Sort By: Relevance

$160K - $200K *

Drive strategic growth and operational excellence in cardiology, fostering physician partnerships and overseeing clinical and financial performance to enhance patient care and organizational success...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$114K - $134K *

Transform billing compliance by leading strategic initiatives, managing audits, and fostering education across teams. Drive adherence to regulations while overseeing a dedicated team to enhance operat...

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$130K - $150K *

Elevate laboratory operations by managing logistics, compliance, and safety in a dynamic research environment. Collaborate with scientists to streamline processes and ensure a well-functioning lab tha...

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$87K *

Lead the charge in maintaining and managing HVAC/Refrigeration systems across the Northeast, ensuring optimal performance and compliance while supervising technicians and overseeing inventory and vend...

Massachusetts, USRemote

Yesterday

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$83K - $133K *

Optimize customer interactions by managing order entry, tracking, and support activities across local business units and agent accounts, ensuring timely delivery and effective communication in a dynam...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$134K - $167K *

Lead the charge in designing and delivering enterprise-grade software solutions. Oversee technical teams, drive innovation, and ensure high-quality outcomes that align with business objectives while m...

Yesterday

  •   5 - 7 years exp.  •   Energy & Utilities

$175K - $210K *

Unlock potential by leading a transformative sales organization across diverse markets. Drive growth through strategic sales initiatives, team development, and robust forecasting, while transitioning...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$80K - $95K *

Champion student well-being by leading Counseling Services, overseeing clinical operations, and fostering collaboration to enhance mental health support for a diverse campus community...

Yesterday

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$190K - $230K *

Lead the accounting and financial reporting functions within a growing healthcare organization. Drive integrity across multiple entities, ensure compliance, and strategize cash management while suppor...

United StatesRemote

Reposted yesterday

  •   11 - 15 years exp.  •   Healthcare

$175K - $263K *

Lead the charge in developing bioanalytical strategies for oncology programs. Collaborate with cross-functional teams and stakeholders to ensure the success of bioanalytical assay design and implement...

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$203K - $305K *

Lead the charge in global hematology trials, translating innovative strategies into impactful clinical studies. Collaborate with cross-functional teams to drive drug development, ensuring high-quality...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$92K - $110K *

Join a team that's dedicated to enhancing manufacturing processes for flight-critical hardware. Collaborate with operators and engineers to ensure quality and efficiency in sheet metal fabrication, we...

Yesterday

  •   Less than 5 years exp.  •   Aerospace & Defense

$107K - $143K *

Drive digital transformation by guiding lower-enterprise clients in leveraging data. Utilize solution selling to create tailored software solutions and manage complex sales cycles, collaborating cross...

Massachusetts, USRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Business Services

$134K - $223K *

Lead the charge in optimizing production operations for aircraft engines, driving safety, quality, and efficiency. Collaborate with a skilled team to implement continuous improvement strategies and ad...

Yesterday

  •   5 - 7 years exp.  •   Aerospace & Defense

$180K *

Champion the paid funnel strategy to drive capital into our real estate vertical. Own the entire process from ad creation to investor engagement, ensuring a seamless transition to the investor relatio...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Business Services

$110K - $130K *

Advance your career by leading the internal audit function, ensuring effective governance, risk management, and compliance. Drive strategic audit planning and execution while fostering a culture of in...

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$218K - $264K *

Drive innovative clinical trial designs and statistical analysis, collaborating with cross-functional teams to ensure regulatory compliance and quality deliverables while mentoring team members and co...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$350K - $425K *

Transform clinical development by leading strategic oncology trials, ensuring medical oversight and regulatory compliance while collaborating across teams to drive innovative drug strategies from earl...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Drive quality assurance initiatives by building automated test suites and collaborating with engineering teams to ensure performance, reliability, and security in a rapidly growing tech environment fo...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$182K - $291K *

Pioneer advanced electronic hardware development by leading architecture, driving technical decisions, and mentoring engineers. Shape the future of complex systems through innovative solutions and cro...

Yesterday

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$135K - $160K *

Lead the strategic design and management of comprehensive benefits programs, ensuring alignment with employee needs and company objectives. Drive innovation and compliance while enhancing employee eng...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$182K - $291K *

Champion innovation by leading the architecture and development of advanced electronic hardware systems. Leverage deep technical expertise and mentorship to drive critical decisions and enhance engine...

Yesterday

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Lead the development and delivery of innovative digital products, collaborating with cross-functional teams to align strategies with business goals and enhance customer experiences through data-driven...

Yesterday

  •   5 - 7 years exp.  •   Media

$75K - $90K *

Join a team that's dedicated to providing high-quality, safe nursing care while coordinating patient treatment and supervising staff. This role emphasizes clinical excellence and resource management t...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Grow your career by driving revenue growth in the acute care market through new customer acquisition and account expansion. Manage the full sales lifecycle while collaborating with internal teams to d...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.