Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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1,000+

Jobs in Massachusetts

Average Salary in USD

Average Salary: $125,903

Sort By: Relevance

$68K - $103K *

Champion contract negotiation and management, ensuring timely delivery of legal agreements and compliance with project timelines. Collaborate closely with clinical teams across North America and Europ...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Healthcare

$157K - $242K *

Join a team that's shaping groundbreaking hardware solutions by defining system architecture, integrating cross-functional requirements, and leading technical direction for complex, production-ready d...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$116K - $210K *

Help us optimize subcontractor performance by providing strategic oversight and guidance. Collaborate with leadership and teams to ensure alignment with program objectives, while mentoring junior staf...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Technical Services

$150K - $200K *

Drive excellence in clinical quality and operational performance at a healthcare facility. Lead a high-performing team to achieve growth, ensure patient safety, and foster strong physician partnership...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$95K - $250K *

Accelerate progress at homeowners' energy efficiency by conducting assessments, diagnosing issues, and recommending solutions. Engage with clients to enhance their energy savings while driving sales a...

Reposted yesterday

  •   Less than 5 years exp.  •   Energy & Utilities

$100K - $223K *

Transform product strategy and execution by leading cross-functional teams, ensuring alignment with business goals and user needs. Drive innovation through emerging technologies while managing timelin...

RemoteRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Elevate user experiences by designing and building intuitive interfaces for scientific applications. Collaborate with cross-functional teams to deliver reliable, data-rich products that enhance the wo...

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $95K *

Drive customer success by delivering expert UAS support, training, and demonstrations. Collaborate with sales and program teams to enhance operational effectiveness and ensure mission readiness for de...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Aerospace & Defense

$162K - $208K *

Empower your career by providing essential optometry services to residents in nursing and assisted living facilities. Enjoy flexible scheduling, competitive compensation, and a supportive environment...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$125K - $132K *

Champion the design of agent-ready workflows by translating complex business processes into clear requirements. Collaborate with product teams to enhance AI capabilities and ensure seamless human-agen...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$125K - $150K *

Lead the development and governance of BIM standards while creating coordinated 3D factory layouts. Collaborate with cross-functional teams to integrate equipment and optimize plant design systems for...

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$100K - $180K *

Join a team that's transforming drug discovery through innovative computational chemistry. Collaborate with experts to drive target selection and enhance drug design technologies, contributing to impa...

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$174K - $374K *

Strategize clinical oversight and drive innovative medical management programs. Collaborate with a multidisciplinary team to enhance member care outcomes while representing the organization to externa...

RemoteRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead the end-to-end ownership of Salesforce systems, integrations, and compliance in a HIPAA-regulated environment. Collaborate with R&D and Operations teams to enhance platform functionality and stre...

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$120K *

Empower operational excellence by managing asset utilization across multiple locations. Collaborate with teams to optimize inventory, control costs, and enhance performance, ensuring efficient asset d...

Yesterday

  •   5 - 7 years exp.  •   Hospitality & Recreation

$124K - $280K *

Champion the testing and quality assurance processes, leading teams to evaluate software functionality. Utilize technical expertise and strategic insights to ensure software meets rigorous standards w...

Reposted yesterday

  •   5 - 7 years exp.  •   Legal & Accounting

$238K - $322K *

Transform payer access strategies by leading national accounts, engaging decision-makers, and ensuring seamless coverage from FDA approval to patient access. Drive impactful relationships and innovati...

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$190K - $235K *

Shape the future of our NetSuite ERP practice by leading a dynamic team, driving strategic initiatives, and ensuring exceptional project delivery while fostering a culture of excellence and collaborat...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$97K - $149K *

Drive impactful digital media strategies by leading a talented team, managing client campaigns, and ensuring excellence in execution. Collaborate with stakeholders to optimize performance and deliver...

Yesterday

  •   5 - 7 years exp.  •   Media

$254K - $382K *

Pioneer innovative clinical strategies as a senior medical leader, driving excellence in study execution and client engagement. Collaborate with cross-functional teams to enhance patient care and oper...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$125K - $150K *

Drive total rewards strategy by managing compensation, benefits, and equity programs. Lead initiatives to ensure competitive, fair, and transparent offerings while supporting a growing workforce throu...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Advance your career by driving digital sales growth and e-commerce strategies. Collaborate with cross-functional teams to enhance revenue and readership for e-books, focusing on key digital accounts a...

Yesterday

  •   Less than 5 years exp.  •   Media

$95K - $115K *

Join a team that's dedicated to enhancing ERP solutions for colleges and universities. As a consultant, you'll collaborate on Ellucian Banner implementations, ensuring client needs are met within scop...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$150K - $180K *

Drive growth by building trusted client relationships and leveraging data insights in the Financial Services Industry, while translating commercial challenges into impactful data-driven solutions for...

Reposted yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $180K *

Drive growth in the Financial Services Industry by leveraging data insights and building trusted client relationships. Collaborate with cross-functional teams to deliver tailored solutions that meet e...

Boston, MARemote

Yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.