Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,016

Sort By: Relevance

$100K - $120K *

Join our team to oversee the comprehensive operations of a PACE program, ensuring effective service delivery, compliance, and financial performance while fostering a culture of innovation and teamwork...

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$145K - $175K *

Pioneer the future of data center construction by leading innovative manufacturing strategies, ensuring seamless integration of offsite components, and driving efficiency through advanced technologies...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$109K - $186K *

Champion business growth across European defense markets by developing strategies, engaging stakeholders, and managing sales cycles. Build long-term relationships to position solutions as the preferre...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$125K - $150K *

Drive new business growth by leveraging industry relationships and expertise in AdTech. Own the sales cycle, navigate complex deals, and collaborate with internal teams to deliver technology-driven ad...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$121K - $170K *

Lead the charge in delivering exceptional customer experiences through strategic oversight and collaboration across teams, ensuring operational excellence and strong client outcomes in a dynamic envir...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Lead the charge in medication management and patient care as a Clinical Pharmacist. Collaborate with healthcare teams to ensure safe medication practices, oversee pharmacy operations, and educate futu...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$104K *

Unlock your potential as a Physical Therapist, evaluating patients, creating treatment plans, and collaborating with a dedicated team in both Home Health and SNF settings. Enjoy a flexible weekend sch...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$112K - $271K *

Lead the charge in transforming manufacturing environments by designing integrated IT and OT architectures. Collaborate with stakeholders to enhance operational efficiency and drive digital innovation...

1 week ago

  •   8 - 10 years exp.  •   Business Services

$84K - $140K *

Champion procurement excellence by driving strategy and execution for advanced manufacturing needs in Government and Public Services. Collaborate with teams to optimize supplier relationships and ensu...

1 week ago

  •   5 - 7 years exp.  •   Business Services

$95K - $115K *

Transform regional sales operations by leading high-performing teams, driving growth, and optimizing execution across multiple markets. Foster talent development and ensure operational excellence to a...

1 week ago

  •   5 - 7 years exp.  •   Staffing

$170K - $210K *

Lead the design and implementation of cross-platform solutions in AWS GovCloud, focusing on Informatica architecture, security, and CI/CD practices. Collaborate with multidisciplinary teams to ensure...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$104K - $166K *

Join a team that's dedicated to enhancing cybersecurity operations. As a Senior SOC Analyst, you'll monitor threats, analyze network traffic, and lead incident response efforts while mentoring junior...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$115K - $145K *

Lead security initiatives by collaborating with cross-functional teams to embed security in the software development lifecycle, ensuring robust protection for high-risk product areas while driving ado...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Transform traffic management by optimizing signal systems for efficient movement of people and goods. Collaborate with cross-functional teams to enhance product deployment and support, ensuring safety...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Transportation

$85K - $105K *

Transform project execution by leading a team of engineers and specialists, ensuring quality and safety while fostering client relationships and optimizing operations across multiple U.S. sites...

1 week ago

  •   Less than 5 years exp.  •   Energy & Utilities

$171K - $214K *

Join us to lead the design and oversight of complex models driving customer lifetime value. Collaborate with engineers and business teams to enhance decision-making across marketing, finance, and prod...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$67K - $111K *

Elevate your career by providing critical analysis and programming support for application software, ensuring a comprehensive and integrated information network that meets diverse customer needs and e...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$103K - $192K *

Shape the future of healthcare reimbursement by leading analytics for payor contracting and out-of-network strategies. Collaborate with cross-functional teams to optimize financial outcomes and drive...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Join a team that's dedicated to enhancing employee engagement and performance through strategic HR initiatives. Collaborate with leaders to drive talent development and foster a positive workplace cul...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$158K - $199K *

Join a dynamic team to lead, coach, and develop sales associates, driving revenue growth through strategic execution and talent retention. Foster C-level relationships and enhance team success in a co...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$85K - $90K *

Join a team that's driving revenue growth and building client relationships in the Southeast. As a key brand ambassador, you'll promote exclusive products and deliver exceptional customer experiences...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$125K - $150K *

Accelerate progress at a dynamic organization by leading all aspects of accounting operations, ensuring compliance, and driving efficiency. Mentor global teams while collaborating on strategic initiat...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Drive impactful projects by collaborating across teams to enhance operational efficiency and deliver innovative solutions. Leverage your expertise to influence strategic decisions and contribute to a...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$74K - $99K *

Engage with cross-functional teams to deliver enterprise APIs, ensuring seamless integration and support for mission-critical applications. Collaborate with partners to translate business needs into t...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$105K - $150K *

Empower construction teams by optimizing financial workflows and technology solutions. Serve as a subject matter expert in cost management, collaborating with stakeholders to enhance project cost cont...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.