Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$110K - $130K *

Drive AI-powered marketing initiatives to optimize campaigns, enhance pipeline generation, and leverage automation. Collaborate cross-functionally while experimenting with emerging technologies to red...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Energy & Utilities

$130K - $150K *

Unlock potential by leading the design and integration of secure, resilient network architectures for mission-critical systems, ensuring operational performance and recovery objectives are met through...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$98K - $152K *

Join a dynamic team to lead IT infrastructure managed services, ensuring operational excellence, customer satisfaction, and continuous improvement. Drive strategy and governance while collaborating wi...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$97K - $151K *

Lead the growth of agency relationships to enhance profitability in your territory. Oversee the execution of strategic initiatives, manage agent performance, and deliver training to drive success in G...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$92K - $153K *

Join a team that's dedicated to enhancing patient access by managing reimbursement challenges and providing education to healthcare providers. This role requires strong relationship-building skills an...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$81K - $128K *

Unlock potential by shaping integrated corporate communications strategies that connect software innovation with community impact, bridging B2B and B2C narratives to advance fraud prevention and eleva...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$261K - $308K *

Transform Women's Health engineering by leading a high-impact team to deliver innovative software solutions. Collaborate across functions to shape strategy and drive organizational excellence while en...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$113K - $147K *

Pioneer innovative solutions as a Microsoft Power Platform Architect, leading enterprise-grade design and implementation. Collaborate with stakeholders to enhance efficiency, automate processes, and d...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$120K - $145K *

Shape the future of data protection by leading a high-performing team of analysts. Drive incident response, enhance security strategies, and collaborate with clients to mitigate risks in a fast-paced...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Partner with us to shape the future of talent acquisition and employee engagement. Lead strategies that attract, retain, and support exceptional talent while enhancing the employee experience across a...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$135K - $160K *

Shape the future of partner marketing by building and executing joint plans with key resellers and distributors, driving engagement and pipeline growth through innovative campaigns and strategic commu...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $180K *

Unlock your potential as a Senior Applied AI Engineer, leading teams to design and deliver impactful AI solutions. Drive technical excellence and mentor engineers while shaping the future of AI system...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Transform healthcare data products by leading strategy, execution, and cross-functional collaboration. Drive product-market fit and commercialization for API-based solutions, ensuring alignment with c...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$82K - $92K *

Empower workplace integrity by conducting thorough investigations, collaborating with HR and stakeholders to ensure compliance, and fostering a culture of transparency and trust within the organizatio...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Accelerate sales growth by leading strategies and initiatives across the ANZ market. Collaborate with a multidisciplinary team to drive customer engagement, develop market strategies, and achieve reve...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Transform procurement operations by leading strategy and team management in a regulated manufacturing environment. Drive supplier performance, cost efficiency, and material availability to support pro...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Staffing

$86K - $165K *

Unlock potential by designing innovative electrical hardware for cutting-edge display technologies. Collaborate with cross-functional teams to enhance avionics and ground vehicle displays, ensuring qu...

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$466K - $500K+*

Unlock potential by developing scalable AI/ML model serving infrastructure. Collaborate cross-functionally to enhance performance and availability of high-traffic systems, driving innovation in a dyna...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$156K - $215K *

Empower innovation in advanced networking and enterprise solutions by defining strategic roadmaps and driving product lifecycle planning across high-speed networking, optical technologies, and AI plat...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Transform the Federal landscape by leading enterprise sales efforts, engaging with SES leaders, and driving digital transformation across major accounts. Collaborate with cross-functional teams to ach...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$73K - $98K *

Join a team that's dedicated to excellence in DRG auditing. Leverage your expertise in MS-DRG and APR-DRG coding to ensure accuracy and compliance while working remotely. Enjoy a collaborative environ...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$100K - $175K *

Transform operations by leveraging your expertise in IT and cybersecurity. Collaborate with leaders to enhance processes, drive efficiency, and ensure compliance while mentoring teams and aligning str...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$165K - $225K *

Champion the development of a GPU-accelerated compute platform, enhancing AI training and research capabilities. Collaborate with cross-functional teams to design orchestration systems that optimize r...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$160K - $195K *

Join a team that's redefining account marketing for major clients. Collaborate with cross-functional partners to drive growth, enhance customer engagement, and create tailored marketing strategies tha...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$450K - $475K *

Drive revenue growth by leading a team of Regional Directors, fostering collaboration, and ensuring alignment with company goals. Your leadership will shape the region's success and culture while enha...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.