Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$100K - $120K *

Transform workforce capabilities by leading innovative training and development initiatives. Collaborate with HR and business leaders to align learning strategies with organizational goals, ensuring i...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$106K - $122K *

Advance global immunization efforts by managing strategic partnerships and implementing evidence-based solutions to enhance vaccine demand and delivery in low and middle-income countries, focusing on...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$135K - $175K *

Shape the future of ad experiences by designing engaging offerwall units, balancing player, publisher, and advertiser needs. Collaborate with cross-functional teams to optimize formats, enhance perfor...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$130K *

Shape the future of non-profit engagement by leading sales initiatives, driving pipeline growth, and fostering client relationships. Leverage your strategic sales expertise to elevate our impact and a...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$91K - $109K *

Lead the charge in maintaining financial integrity by overseeing accounting operations, ensuring compliance with nonprofit standards, and managing audits. Collaborate with finance leadership to produc...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Manage and oversee engineering operations, ensuring effective planning, execution, and maintenance of facilities. Collaborate with diverse teams to optimize resources and enhance operational efficienc...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$75K - $99K *

Lead the charge in fostering a culture of safety and quality as you develop and coach a team of technicians. Oversee performance, drive continuous improvement, and collaborate with cross-functional le...

1 week ago

  •   Less than 5 years exp.  •   Food & Beverages

$150K - $180K *

Transform client relationships and drive growth as a leader in digital marketing. Cultivate executive partnerships, mentor teams, and innovate solutions while achieving profitability in a dynamic work...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Champion operational excellence by leading communication strategies and process improvements. Collaborate with leadership and teams to ensure effective information flow and accountability, driving ini...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $200K *

Join a dynamic team to drive growth in the pharmaceutical sector, leveraging your expertise to build relationships, win new business, and deliver impactful solutions that enhance brand performance and...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$90K - $115K *

Join a dynamic team to lead client accounts, translating needs into effective strategies while fostering strong relationships and guiding junior members. Drive successful project execution and proacti...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $167K *

Unlock potential by driving revenue insights and financial modeling, enhancing decision-making across finance and operations. Collaborate with stakeholders to refine processes and improve revenue reco...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Develop and optimize a scalable, geo-distributed database solution while leading a skilled team. Engage in deep technical challenges to enhance performance and reliability across diverse environments...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$99K - $120K *

Join our innovative team to architect and deliver cutting-edge IoT systems for special projects. You'll drive initiatives from concept to field pilot, integrating advanced technologies in a dynamic, c...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Technical Services

$77K - $95K *

Lead the charge in optimizing client websites through strategic SEO initiatives, fostering client relationships, and driving growth opportunities while mentoring junior staff and collaborating with a...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$230K - $368K *

Grow your career with a dynamic team that builds innovative solutions across full stack, focusing on customer needs and delivering impactful results in a fast-paced, startup-like environment...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$183K - $293K *

Contribute to a cutting-edge global privacy program, ensuring compliance with regulations while driving innovative privacy solutions. Collaborate across teams to manage risk and enhance privacy practi...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$140K - $200K *

Join a dynamic team and lead safety compliance for autonomous vehicles. This senior role requires expertise in regulatory engagement, documentation, and safety assurance. Drive industry standards, ens...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Transportation

$90K - $100K *

Tackle new business growth as a key player in driving the sales cycle. Leverage your sales expertise to build relationships with enterprise clients, close deals, and expand market presence while worki...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Legal & Accounting

$175K - $195K *

Unlock potential by leading strategic M&A initiatives across Europe and APAC. Drive deal execution with autonomy, manage due diligence, and collaborate with senior leadership to shape investment strat...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$162K - $170K *

Drive advanced machine learning solutions as a key contributor to our perception team, focusing on deep learning and computer vision to enhance robotics technology and bring innovative models from ide...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$250K - $300K *

Execute innovative strategies to acquire and expand client relationships, leveraging expertise in AI/ML solutions. Be a proactive networker, navigating complex sales cycles to foster business growth a...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $185K *

Unlock potential by driving innovative infrastructure solutions for scalable deployments, collaborating with customers to refine requirements, and enhancing operational efficiency through automation a...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$115K - $180K *

Create a high-impact events program to drive pipeline and revenue. Own strategy, execution, and results of senior-level engagements, ensuring strong alignment with enterprise sales and marketing objec...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$92K *

Join a transformative program to develop your Electrical & Automation skills through hands-on experience, mentorship, and structured training, preparing you for a full-time engineering role in a dynam...

1 week ago

  •   Less than 5 years exp.  •   Food & Beverages

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.