Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$150K - $189K *

Transform global labeling strategies into actionable regional plans, ensuring compliance and quality. Oversee document preparation, vendor management, and cross-functional approvals to deliver timely...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$123K - $202K *

Join our agile team to design and develop cutting-edge Esri software for raster and imagery workflows in ArcGIS Pro using C#, WPF, and C++. Collaborate to create innovative user interfaces while ensur...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Information Technology

$98K - $173K *

Empower businesses by leveraging GIS technology to solve complex spatial challenges. As a geospatial expert, engage with clients to demonstrate innovative solutions and strategies that drive impactful...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Information Technology

$160K - $195K *

Shape the future of payroll and HRIS integrations by ensuring reliability and success. Collaborate with customers and partners to solve technical challenges and enhance the integration experience whil...

RemoteRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$199K - $232K *

Unlock potential by driving social media strategy and engagement across diverse platforms. Collaborate with teams to create compelling content, analyze performance, and enhance brand presence while ad...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $145K *

Pioneer the future of technical content as you drive strategy and execution for Render's content factory, ensuring accuracy and relevance for AI agents and developers. Collaborate closely with teams t...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$146K - $224K *

Elevate clinical development by leading the strategy for biopharma platforms. Drive product lifecycles, collaborate with cross-functional teams, and ensure compliance while transforming workflows into...

RemoteRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Healthcare

$223K - $313K *

Join a distinguished team of physicians to enhance inpatient care quality through expert clinical reviews and utilization management, impacting patient outcomes while enjoying a structured, collaborat...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Shape user experiences by designing intuitive interfaces for a cutting-edge security platform. Collaborate with engineers to create impactful visual workflows, leveraging modern technologies to enhanc...

RemoteRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Business Services

$107K - $143K *

Advance your career by driving strategic GTM solutions, aligning cross-functional teams, and optimizing sales processes to enhance pipeline performance and bookings outcomes in a dynamic environment...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$60K - $115K *

Drive sales growth in agricultural technology by fostering relationships with farmers and partners, promoting innovative crop management solutions, and achieving targets through strategic outreach and...

Sioux City, IARemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$60K - $115K *

Drive farmer engagement and sales of innovative CropVoice products, collaborating closely with stakeholders to enhance agricultural practices and achieve territory objectives through strategic product...

Reposted 6 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$95K - $115K *

Drive product ownership and functional support for Oracle Fusion SCM and Fleet Management. Collaborate with stakeholders to resolve complex issues, enhance processes, and shape the product roadmap whi...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Staffing

$110K - $130K *

Drive project success by implementing Oracle Primavera P6 solutions, optimizing project controls, and integrating with Oracle Cloud applications to enhance scheduling, resource management, and financi...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Staffing

$150K - $180K *

Lead the charge in transforming Oracle HCM practices by driving strategic growth, fostering innovation, and building high-performing teams. Collaborate with clients and partners to deliver exceptional...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Staffing

$246K - $273K *

Build and lead a high-impact marketing organization to drive customer growth, product launches, and performance metrics in a dynamic, Bitcoin-focused environment. Collaborate cross-functionally and ta...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$92K - $105K *

Join a team that's driving innovative SEM strategies for transformative clients. Lead paid search campaigns, mentor a dynamic team, and utilize data-driven insights to optimize performance and achieve...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$95K - $115K *

Serve as a strategic advisor to clients, leading performance marketing initiatives and fostering growth through integrated strategies, analytics, and emerging technologies while mentoring team members...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $120K *

Lead the charge in enhancing patient starts and scan volume through strategic partnerships and targeted marketing initiatives, ensuring territory growth and revenue commitments are met while cultivati...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$215K - $240K *

Shape the future of drug development by leading analytical strategies, ensuring compliance and optimization of processes across lifecycle stages, and collaborating with cross-functional teams and exte...

United StatesRemote

Reposted 6 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$134K - $145K *

Optimize commercial accounting processes by managing revenue, inventory, and accounts receivable. Collaborate with cross-functional teams to ensure accurate financial reporting and drive process impro...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Join a team that's dedicated to operational excellence and safety. Lead a dynamic plant environment, ensuring product quality, employee safety, and profitability while managing resources effectively a...

6 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$68K - $120K *

Lead the charge in managing oncology clinical trials, ensuring efficient operations, compliance, and stakeholder engagement throughout the trial lifecycle while collaborating with various teams and ma...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$63K - $98K *

Champion public service by representing indigent clients in appellate cases. Engage in legal research, draft briefs, and present oral arguments while receiving mentorship from experienced attorneys in...

6 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$140K - $164K *

Develop and lead a high-performing sales team to drive national corporate growth, aligning strategies and processes to achieve ambitious revenue targets while fostering a culture of accountability and...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.