Explore $100K+ Jobs in Illinois

Find high-paying career opportunities across Illinois with Ladders. Browse vetted professional jobs offering salaries of $100,000 or more, from openings in Chicago to roles in cities and communities throughout the state. Whether you’re ready to take the next step in your career or explore a new industry, discover Illinois positions that match your experience and goals.

Career Opportunities Across Illinois

Illinois offers a broad range of professional opportunities, with a concentration of employers and roles in the Chicago area and opportunities across the rest of the state. Explore positions in fields such as finance, technology, healthcare, manufacturing, consulting, and business leadership. Available roles and compensation vary by employer, location, and experience.

Find a Role That Fits Your Experience

Use Ladders to explore professional openings with salaries of $100,000 or more. Review job details, compare opportunities, and focus your search on the locations, industries, and responsibilities that align with your career plans. Check listings for requirements, work arrangements, and compensation details.

Advance Your Career in Illinois

Start your search for a high-paying job in Illinois by browsing current listings and applying to roles that fit your qualifications. New opportunities can become available over time, so check back regularly to find the latest vetted professional jobs on Ladders.

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1,000+

Jobs in Illinois

Average Salary in USD

Average Salary: $117,810

Sort By: Relevance

$135K - $160K *

Join a dynamic team to architect and implement a next-gen Design System, ensuring consistent, accessible experiences across products. Collaborate with cross-functional teams to drive technical alignme...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Food & Beverages

$201K - $251K *

Elevate access strategies and marketing initiatives for oncology products, focusing on non-clinical value propositions. Collaborate cross-functionally to ensure successful product launches and effecti...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$175K - $210K *

Lead and manage clinical development programs, ensuring high-quality data generation and compliance. Oversee teams, mentor staff, and collaborate cross-functionally to drive strategic clinical initiat...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $97K *

Shape the future of patient care by leading nursing assessments and interventions. Collaborate with interdisciplinary teams to ensure optimal health outcomes for patients and families in a supportive...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$255K - $424K *

Lead the development and execution of Immunology access services strategy, ensuring seamless patient and provider experiences. Collaborate cross-functionally to enhance reimbursement initiatives and d...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$142K - $160K *

Champion privacy compliance in the Neurology therapeutic area, providing expert guidance on data protection, contract negotiation, and training. Collaborate with cross-functional teams to ensure adher...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Shape your career by managing client relationships and driving AI solutions in the automotive sector. Leverage your expertise in conversational AI and marketing automation to enhance performance metri...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$70K - $150K *

Drive growth in oral surgery practices by building relationships, pursuing new sales opportunities, and achieving targets. Leverage your sales expertise to deliver exceptional customer service and sup...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$163K - $214K *

Elevate your career by leading major installation projects, ensuring safety and quality while managing relationships with customers and teams. Drive project success through effective planning, coordin...

3 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$150K - $500K *

Unlock potential by driving mortgage transactions with innovative technology and dedicated support. Leverage robust investor access for swift approvals and closings. Ideal for experienced professional...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $110K *

Empower business transformation by bridging functional and technical gaps in Oracle EBS and Cloud. Drive solution delivery, optimize processes, and ensure data integrity while collaborating with stake...

3 days ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$100K - $110K *

Partner with us to bridge business processes and technical execution in Oracle EBS and Cloud. You'll analyze requirements, configure modules, and deliver solutions that align with strategic objectives...

3 days ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$80K - $110K *

Design and develop advanced analytics solutions, transforming complex healthcare data into actionable insights using Azure Databricks and Power BI. Collaborate with cross-functional teams to enhance r...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$185K - $235K *

Drive successful execution of large-scale industrial construction projects, overseeing all phases from award to closeout. Lead diverse teams, manage budgets, and ensure client satisfaction while maint...

3 days ago

  •   8 - 10 years exp.  •   Staffing

$95K - $147K *

Lead program development and management for HDFS products, focusing on value propositions, product success factors, and channel strategies to drive profitability and growth while ensuring strong provi...

Reposted 3 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Join us to minimize access barriers for patients and providers, executing market access plans across multiple states. Collaborate with healthcare professionals to resolve reimbursement issues and enha...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$71K - $90K *

Empower communities by driving peer-to-peer fundraising initiatives, building strategic partnerships, and coaching volunteers. This role combines travel and remote work, allowing you to make a signifi...

3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$150K - $180K *

Lead operational excellence and strategic execution for the Global Technology India office, enhancing employee engagement and driving scalable growth through effective governance and operational rigor...

3 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$110K - $130K *

Champion project success by managing design and coordination for aviation, transit, and commercial building projects. Collaborate with clients and stakeholders to exceed expectations while ensuring fi...

3 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$100K - $137K *

Lead the enhancement and support of the Workday Finance environment, driving process improvements and issue resolutions while acting as the primary resource for finance stakeholders and end-user train...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $137K *

Join a dynamic team as a Senior Systems Accountant, enhancing the Workday Finance platform through expert support, issue resolution, and collaboration with stakeholders to drive process improvements a...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$150K - $350K *

Join a team that's building scalable, high-performance backend systems using TypeScript. Collaborate across functions to optimize trading solutions and tackle complex challenges in the blockchain spac...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Drive compliance excellence by developing policies and controls, ensuring alignment across teams, and managing risk in a dynamic environment. Collaborate with leadership to enhance compliance training...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$120K - $145K *

Empower your career by leading the design and implementation of Oracle Field Service solutions for utility organizations. Collaborate with stakeholders to enhance operational performance and customer...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Staffing

$70K - $106K *

Transform operational data into actionable insights while collaborating with cross-functional teams to support business decisions and enhance efficiency. Leverage analytical skills to drive performanc...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Illinois?question toggle

    Illinois listings may include professional and leadership roles in areas such as finance, technology, healthcare, manufacturing, consulting, and business operations. Job availability and qualifications vary by employer.

  • Are there high-paying jobs outside Chicago?question toggle

    Yes. While many opportunities are based in the Chicago area, listings may also be available in other Illinois cities and communities. Search by location to explore current openings.

  • How can I find Illinois jobs that pay $100,000 or more?question toggle

    Browse Illinois listings on Ladders and review each job’s salary information, qualifications, location, and work arrangement. Listings feature vetted professional opportunities with salaries of $100,000 or more.

  • Do Illinois job listings include remote or hybrid roles?question toggle

    Some listings may offer remote or hybrid work, depending on the employer and position. Check each job description for the specific work arrangement.