Discover professional opportunities across California with Ladders. From established business centers to growing regional economies, the state offers senior-level roles in technology, healthcare, finance, entertainment, manufacturing, and more. Browse vetted job listings with salaries of $100,000 or higher and find positions that align with your experience and career goals.
California’s diverse economy supports leadership and specialized roles at companies of all sizes. Depending on your background, you may find opportunities in software and technology, life sciences, healthcare, financial services, clean energy, media, aerospace, and professional services. Job availability and compensation vary by role, employer, and location.
Explore openings in major employment centers such as Los Angeles, San Francisco, San Diego, San Jose, Sacramento, and surrounding communities. Listings may include on-site, hybrid, and remote arrangements; review each posting for its work location and requirements.
Use Ladders to focus your search on vetted professional jobs paying $100,000 or more. Review role responsibilities, qualifications, compensation details, and workplace expectations, then apply directly to opportunities that fit your goals. Keep your profile and resume current so employers can better understand your experience.
Infection Preventionist, Acute (RN)
$163K - $229K *
Lead hospital-wide infection control initiatives, providing expert consultation and education to enhance patient care and safety. Collaborate with healthcare personnel to implement performance improve...
1 week ago
$87K - $110K *
Design and implement robust database architectures to enhance business processes. Oversee data ingestion, security, and performance optimization within the Enterprise Data Warehouse, ensuring complian...
6 days ago
Registered Nurse, Out-Patient Case Manager
$104K *
Unlock potential by leading care coordination for patients with chronic diseases. Collaborate with an interdisciplinary team to provide comprehensive case management, ensuring optimal health outcomes...
3 days ago
$129K - $182K *
Engineer innovative AI applications and agentic workflows to enhance enterprise efficiency, transforming conceptual ideas into functional prototypes while ensuring adherence to security and responsibl...
Reposted 3 weeks ago
RN Territory Clinical Manager, Home Health Full Time
$90K - $110K *
Empower clinical excellence by overseeing patient care operations and ensuring compliance. Lead interdisciplinary teams in delivering high-quality healthcare while mentoring staff and managing key per...
Reposted 6 days ago
Provider Engagement and Performance Specialist III
$88K - $142K *
Take ownership of provider relationships, driving engagement and performance improvement through strategic communication, data analysis, and cross-functional collaboration to enhance value-based care...
1 week ago
$110K - $125K *
Lead the charge in delivering comprehensive remote cancer care, collaborating with a multidisciplinary team to enhance patient outcomes. Utilize your extensive oncology experience and telehealth exper...
1 week ago
$120K - $145K *
Transform the future of quality assurance by building scalable systems that audit training data, optimize workflows, and improve vendor collaboration in a fast-paced, innovative environment...
Reposted 3 weeks ago
Registered Nurse, Out-Patient Case Manager
$104K *
Join a team that's dedicated to enhancing patient care through effective case management and coordination. Collaborate with an interdisciplinary team to support patients with chronic diseases and lead...
3 days ago
$150K - $180K *
Champion provider activation by leading a dynamic team to enhance response rates and streamline prior authorizations, driving impactful outcomes for patients and partners. Collaborate across functions...
2 weeks ago
$166K - $191K *
Shape the future of audiological care by leading teams in diagnosing and treating hearing and balance disorders while enhancing patient outcomes through innovative therapies, education, and cross-depa...
Reposted 5 days ago
Provider Engagement and Performance Specialist II
$77K - $123K *
Elevate provider engagement by coordinating initiatives that strengthen relationships with stakeholders. Monitor projects, ensure compliance, and support cross-functional teams to enhance performance...
1 week ago
Advanced Practice Provider (NP or PA): Palliative Care
$120K - $155K *
Empower patients by delivering compassionate, patient-centered palliative care through virtual consultations. Collaborate with a dynamic team to enhance quality of life for members with complex needs...
2 weeks ago
Clinical Research Program Manager, Hybrid
$110K - $130K *
Empower clinical research initiatives by managing a disease-focused portfolio, leading a dedicated team, and ensuring compliance and efficiency in trial operations while fostering collaboration and st...
3 days ago
Clinical Research Program Manager, Hybrid
$110K - $130K *
Manage a clinical research portfolio, leading a dedicated team to drive innovative research. Oversee operations, ensure compliance, and collaborate with stakeholders to enhance program success and eff...
3 days ago
Account Management Associate II - NCAL
$72K - $93K *
Transform customer engagement by supporting account strategies, enhancing team communications, and driving KPIs. Collaborate with cross-functional teams to ensure a positive customer experience and ef...
5 days ago
Manager, Quality & Patient Safety (Acute Clinician)
$148K - $238K *
Lead the charge in improving patient safety and clinical quality across facilities. You'll manage staff, analyze performance metrics, and collaborate with teams to ensure compliance and enhance health...
Reposted 1 week ago
$76K - $120K *
Drive quality nursing care by assessing patient needs, providing education, and collaborating with a multidisciplinary team to ensure effective treatment and compassionate support for patients and the...
3 weeks ago
$76K - $120K *
Join a passionate healthcare team dedicated to delivering quality nursing care, emphasizing patient education, safety, and emotional support while collaborating with a multidisciplinary team to enhanc...
3 weeks ago
$100K - $130K *
Manage the coordination of clinical sites for student experiences, ensuring effective placements, evaluations, and partnerships. Collaborate with faculty and community to enhance student success and u...
1 week ago
$100K - $130K *
Join a team that's dedicated to enhancing clinical education by coordinating student placements, evaluating performance, and fostering community partnerships to ensure a superior learning experience i...
1 week ago
$120K - $145K *
Transform data into actionable insights by partnering with marketing teams to enhance pipeline generation and optimize decision-making, while mastering analytics infrastructure and driving automation...
Reposted 1 week ago
$113K - $197K *
Lead regulatory and compliance oversight for Operations, ensuring accuracy and efficiency. Collaborate with enterprise partners to enhance operational processes, implement automation, and drive contin...
2 days ago
Category Management Specialist V - Medical Software
$178K - $230K *
Engage with us to lead category strategies, drive supplier negotiations, and foster relationships with stakeholders. Utilize analytics for data-driven decisions while supporting sustainability initiat...
5 days ago
Research Nurse III, RN, Clinical Trials
$161K - $209K *
Transform clinical research by leading innovative nursing practices, collaborating with interdisciplinary teams, and ensuring compliance while enhancing patient care and safety through evidence-based...
5 days ago
What types of $100,000+ jobs can I find in California?
California listings may include senior and specialized roles in technology, healthcare, finance, life sciences, entertainment, clean energy, manufacturing, and other fields. Available positions depend on current employer needs.
Where in California can I search for jobs?
You can explore opportunities across the state, including major employment hubs such as Los Angeles, San Francisco, San Diego, San Jose, and Sacramento. Check each posting for its specific location and work arrangement.
Are all jobs on this page guaranteed to pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for compensation information and details, since pay can vary by position and employer.
Can I find remote or hybrid California jobs?
Some listings may offer remote or hybrid work, while others require on-site work. The job posting provides the employer’s location and work arrangement requirements.
How can I improve my California job search?
Narrow your search by role, location, industry, and work arrangement. Keep your resume and profile updated, and carefully compare each opportunity’s qualifications and compensation details.