Discover professional opportunities across California with Ladders. From established business centers to growing regional economies, the state offers senior-level roles in technology, healthcare, finance, entertainment, manufacturing, and more. Browse vetted job listings with salaries of $100,000 or higher and find positions that align with your experience and career goals.
California’s diverse economy supports leadership and specialized roles at companies of all sizes. Depending on your background, you may find opportunities in software and technology, life sciences, healthcare, financial services, clean energy, media, aerospace, and professional services. Job availability and compensation vary by role, employer, and location.
Explore openings in major employment centers such as Los Angeles, San Francisco, San Diego, San Jose, Sacramento, and surrounding communities. Listings may include on-site, hybrid, and remote arrangements; review each posting for its work location and requirements.
Use Ladders to focus your search on vetted professional jobs paying $100,000 or more. Review role responsibilities, qualifications, compensation details, and workplace expectations, then apply directly to opportunities that fit your goals. Keep your profile and resume current so employers can better understand your experience.
$95K - $115K *
Empower clinical research excellence by leading cross-functional teams to ensure timely, quality execution of studies. Drive operational strategies, manage budgets, and foster innovation while navigat...
4 days ago
Onsite Care Coordination Nurse
$71K - $97K *
Pioneer the integration of comprehensive assessments and discharge planning to ensure coordinated, quality care for admitted members, enhancing health outcomes and optimizing member wellness through c...
Reposted 2 weeks ago
Sr Associate IS Analyst - Process Development Labs
$110K - $130K *
Contribute to the development of secure lab technology solutions, supporting scientists with reliable systems and automation tools. Collaborate across teams to enhance infrastructure and ensure optima...
3 weeks ago
Nurse Practitioner or Physician Assistant, HPB Surgical Oncology (Sacramento, CA & Roseville, CA)
$110K - $130K *
Engage as a key clinician in a pioneering outpatient surgical oncology program, focusing on complex GI malignancies. Collaborate with a multidisciplinary team to provide comprehensive care and shape t...
3 days ago
Hybrid Nurse Practitioner/Physician Assistant - San Gabriel Valley
$130K - $195K *
Shape the future of patient care by delivering compassionate, proactive support in a hybrid role. Collaborate with an interdisciplinary team to enhance health outcomes for vulnerable populations throu...
3 days ago
$117K - $188K *
Drive quality data management by leading a skilled team to optimize operations, ensuring compliance and accuracy in delivering HEDIS and Survey data to stakeholders while fostering performance improve...
Reposted 2 weeks ago
Clinical Trials Systems Analyst, Sr.
$95K - $127K *
Drive clinical research excellence by optimizing systems and workflows. Collaborate with stakeholders to enhance technology solutions, ensuring compliance and efficiency in pediatric care research ope...
3 weeks ago
$72K - $113K *
Unlock potential by coordinating patient-centered transitions of care, ensuring timely discharge planning, and collaborating with healthcare teams to enhance patient outcomes and reduce readmissions i...
2 weeks ago
Senior/Principal Statistician Consultant --TA - Oncology (Remote)
$120K - $145K *
Drive statistical excellence in oncology clinical trials, ensuring accuracy and quality of deliverables while collaborating with diverse teams to support impactful research across various health secto...
1 week ago
$67K - $112K *
Drive revenue growth by managing existing accounts and developing new ones. Leverage market insights and customer relationships to exceed sales targets while ensuring compliance with company guideline...
Reposted 1 week ago
IT SAP Functional Analyst, Expert - EHSM
$128K - $173K *
Elevate IT solutions by driving SAP EHSM implementation and support. Collaborate across teams to analyze, design, and enhance Health and Safety processes, ensuring best practices while delivering busi...
Reposted 1 week ago
Actuary, Pricing - Individual MA
$129K - $177K *
Join a team that's shaping innovative pricing strategies for Medicare Advantage products. Collaborate cross-functionally to analyze market data, establish financial metrics, and drive profitable growt...
Reposted 3 days ago
Director of Financial Planning and Analysis
$183K - $238K *
Champion financial planning and analysis by leading forecasting, modeling, and strategic insights. Collaborate with executives to drive performance and ensure alignment with organizational goals, enha...
2 days ago
Corporate Strategy Project Analyst
$84K - $103K *
Contribute to Corporate Strategy by enhancing project execution, governance, and reporting. Collaborate with project teams and stakeholders to maintain operational efficiency and drive project success...
Reposted 6 days ago
Manager, Analytics and Market Research - Eye Care
$112K - $135K *
Take ownership of analytics and market research to drive insights for eyecare brands. Collaborate with teams to inform strategic decisions, enhance brand performance, and automate reporting processes...
3 days ago
Senior Customer Success Manager - Healthcare
$110K - $130K *
Drive customer success by managing relationships and ensuring product adoption. Collaborate with teams to mitigate risks, enhance customer experience, and create growth opportunities while mentoring p...
1 week ago
$110K - $130K *
Lead the charge in developing and managing a comprehensive coding education program while overseeing audits and compliance initiatives. Collaborate with clinical leaders to enhance coding accuracy and...
Reposted yesterday
$159K - $211K *
Join us in transforming quality operations by leading a robust PACE quality program, ensuring compliance and care excellence while collaborating cross-functionally to enhance participant outcomes and...
3 weeks ago
Biological & Lab Safety Specialist
$77K - $119K *
Contribute to a culture of safety, ensuring compliance and risk management in biological and laboratory safety programs. Engage with teams to strengthen safe practices related to hazardous materials a...
Reposted 1 week ago
Project Manager, Health Systems
$110K - $130K *
Join us to lead complex health system implementations, coordinating across teams and stakeholders to ensure successful project delivery while managing risks and dependencies effectively...
1 week ago
Senior Manager Regulatory Affairs, Global Reg Strategy US & Canada
$130K - $155K *
Lead the development and execution of regulatory strategies for US and Canada, ensuring compliance and effective communication with health authorities. Collaborate cross-functionally to support produc...
3 weeks ago
$80K - $95K *
Lead the charge in enhancing community health by conducting assessments and providing interventions for members facing social barriers. Collaborate with interdisciplinary teams to ensure effective car...
3 days ago
$80K - $95K *
Drive impactful social interventions by assessing health needs and linking members to community resources. Collaborate with interdisciplinary teams to enhance care for Medi-Cal populations, ensuring s...
3 days ago
Sr Mgr, Health Economic, Reimbursement
$145K - $205K *
Lead the charge in advancing economic value strategies for innovative health therapies, fostering cross-functional collaboration, and translating complex data into actionable insights to enhance marke...
Reposted 3 weeks ago
RN Director of Clinical Services
$120K - $125K *
Manage and oversee patient care activities to ensure high-quality hospice services. Lead a team of clinicians, ensuring compliance with regulations while fostering a compassionate care environment for...
1 week ago
What types of $100,000+ jobs can I find in California?
California listings may include senior and specialized roles in technology, healthcare, finance, life sciences, entertainment, clean energy, manufacturing, and other fields. Available positions depend on current employer needs.
Where in California can I search for jobs?
You can explore opportunities across the state, including major employment hubs such as Los Angeles, San Francisco, San Diego, San Jose, and Sacramento. Check each posting for its specific location and work arrangement.
Are all jobs on this page guaranteed to pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for compensation information and details, since pay can vary by position and employer.
Can I find remote or hybrid California jobs?
Some listings may offer remote or hybrid work, while others require on-site work. The job posting provides the employer’s location and work arrangement requirements.
How can I improve my California job search?
Narrow your search by role, location, industry, and work arrangement. Keep your resume and profile updated, and carefully compare each opportunity’s qualifications and compensation details.