Discover professional opportunities across California with Ladders. From established business centers to growing regional economies, the state offers senior-level roles in technology, healthcare, finance, entertainment, manufacturing, and more. Browse vetted job listings with salaries of $100,000 or higher and find positions that align with your experience and career goals.
California’s diverse economy supports leadership and specialized roles at companies of all sizes. Depending on your background, you may find opportunities in software and technology, life sciences, healthcare, financial services, clean energy, media, aerospace, and professional services. Job availability and compensation vary by role, employer, and location.
Explore openings in major employment centers such as Los Angeles, San Francisco, San Diego, San Jose, Sacramento, and surrounding communities. Listings may include on-site, hybrid, and remote arrangements; review each posting for its work location and requirements.
Use Ladders to focus your search on vetted professional jobs paying $100,000 or more. Review role responsibilities, qualifications, compensation details, and workplace expectations, then apply directly to opportunities that fit your goals. Keep your profile and resume current so employers can better understand your experience.
Clinical Manager - Home Health (Hybrid)
$100K - $120K *
Drive excellence in patient care by supervising a dedicated clinical team, guiding processes, and ensuring high-quality outcomes. Your leadership will support the success of our home health operations...
3 weeks ago
User Security & Access Analyst - Hybrid - 140760
$100K - $140K *
Advance your career by managing complex identity and access security solutions. This pivotal role requires expertise in user provisioning, Epic security, and compliance, driving operational security p...
Reposted 3 weeks ago
User Security & Access Analyst - Hybrid - 140760
$100K - $140K *
Champion user security and access management by overseeing complex identity and provisioning tasks, ensuring compliance with organizational standards, and supporting collaboration across teams to enha...
Reposted 3 weeks ago
$120K - $160K *
Empower operational excellence by mapping, designing, and streamlining processes. Collaborate closely with the executive team to build a scalable organizational structure and integrate knowledge manag...
Reposted 2 days ago
$95K - $115K *
Empower healthcare delivery by collaborating with clinical teams to ensure timely access to quality care. This role involves managing complex utilization reviews, coordinating care, and supporting reg...
1 week ago
Senior Program and Policy Consultant-Medicaid
$100K - $115K *
Drive impactful change by leading Medicaid initiatives that enhance community health. Collaborate with state agencies, utilize your expertise in Medicaid policies, and advance your career in a support...
3 weeks ago
$145K - $160K *
Pioneer data-driven insights by collaborating with cross-functional teams to enhance business strategies. Leverage advanced analytics and visualization skills to drive operational improvements and sup...
1 week ago
$72K - $116K *
Drive quality assurance initiatives by leading data testing strategies, overseeing validation processes, and guiding technical teams in the healthcare domain. Translate complex data risks into actiona...
2 weeks ago
$67K - $94K *
Manage workflow and activities at a Care Center, providing leadership feedback and recommendations. Collaborate with teams to enhance operational efficiency while ensuring high-quality customer servic...
1 week ago
$230K - $300K *
Transform your team's output by leading engineering efforts, driving technical decisions, and fostering growth. Balance hands-on coding with team management to deliver high-quality solutions and enhan...
1 week ago
Customer Success Manager (Healthcare SAAS)
$90K - $110K *
Engage with healthcare clients to maximize value from innovative software solutions. Collaborate on onboarding, account health, and usage strategies to enhance customer satisfaction, adoption, and ret...
2 weeks ago
$75K - $90K *
Elevate your career by joining a dynamic team of Clinical Laboratory Scientists. Take ownership of testing responsibilities, ensuring quality control and accurate results while working independently i...
2 weeks ago
$75K - $90K *
Join a team that's dedicated to excellence in clinical testing. Leverage your expertise as a Clinical Laboratory Scientist, performing vital tests independently while ensuring quality control and effe...
2 weeks ago
$124K - $187K *
Drive innovative modeling strategies for cell therapy products, optimizing dose selection and patient outcomes through advanced pharmacometric techniques and cross-functional collaboration in drug dev...
1 week ago
$75K - $88K *
Make your mark at the forefront of data analysis by delivering impactful reports and insights that drive decision-making across multiple programs, ensuring the highest standards in data quality and co...
Reposted 4 days ago
Staff Engineer, Detection and Response
$225K - $281K *
Lead the charge in shaping detection and response strategies, driving hands-on initiatives to enhance security architecture and incident management. Collaborate across teams to ensure robust threat de...
1 week ago
Executive Director, Health Economics & Outcomes Research (HEOR)
$246K - $332K *
Shape the future of health economics and outcomes research by leading strategic initiatives across the nephrology portfolio, ensuring high-quality evidence generation and collaboration with cross-func...
6 days ago
Sr. Data Analyst, Customer Analytics (Insurance)
$84K - $120K *
Accelerate insights generation as a key member of the Customer Analytics team, transforming raw data into actionable recommendations that enhance client retention, drive growth, and refine operational...
Reposted 1 week ago
$197K - $276K *
Elevate nursing education by designing and implementing programs that enhance staff competency, ensuring compliance with healthcare standards and fostering professional development through innovative...
2 weeks ago
Actuarial Analyst - Commercial P&C Insurance
$150K - $200K *
Unlock potential by building and refining actuarial models for property insurance. Collaborate with a dynamic team to analyze data, produce insights, and influence client decisions in a hands-on, hybr...
1 week ago
RN Case Manager Hospice - San Jose, CA
$85K - $100K *
Join a team that's dedicated to providing compassionate end-of-life care. As an RN Case Manager, you'll coordinate with healthcare professionals to ensure patients receive tailored support and resourc...
5 days ago
$118K - $177K *
Optimize global HR technology programs by leading Workday Time Tracking, Absence, and Benefits integrations. Drive system enhancements, ensure data accuracy, and support payroll processes while collab...
3 weeks ago
Director, Risk Adjustment Strategies and Initiatives
$149K - $254K *
Join a dynamic team to enhance risk adjustment strategies and initiatives. Lead transformative projects, ensure compliance and optimize clinical documentation to support organizational growth and effi...
Reposted 3 weeks ago
Information Security Risk and Governance Specialist, Consultant
$110K - $130K *
Join a team that's dedicated to enhancing information security governance and risk management. In this role, you'll support compliance efforts, manage audits, and develop security metrics to ensure ro...
3 weeks ago
Information Security Risk and Governance Specialist, Consultant
$110K - $130K *
Lead the charge in enhancing information security governance and risk management practices. Collaborate with teams to ensure compliance with regulatory standards, support audit readiness, and drive co...
3 weeks ago
What types of $100,000+ jobs can I find in California?
California listings may include senior and specialized roles in technology, healthcare, finance, life sciences, entertainment, clean energy, manufacturing, and other fields. Available positions depend on current employer needs.
Where in California can I search for jobs?
You can explore opportunities across the state, including major employment hubs such as Los Angeles, San Francisco, San Diego, San Jose, and Sacramento. Check each posting for its specific location and work arrangement.
Are all jobs on this page guaranteed to pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for compensation information and details, since pay can vary by position and employer.
Can I find remote or hybrid California jobs?
Some listings may offer remote or hybrid work, while others require on-site work. The job posting provides the employer’s location and work arrangement requirements.
How can I improve my California job search?
Narrow your search by role, location, industry, and work arrangement. Keep your resume and profile updated, and carefully compare each opportunity’s qualifications and compensation details.