Discover professional opportunities across California with Ladders. From established business centers to growing regional economies, the state offers senior-level roles in technology, healthcare, finance, entertainment, manufacturing, and more. Browse vetted job listings with salaries of $100,000 or higher and find positions that align with your experience and career goals.
California’s diverse economy supports leadership and specialized roles at companies of all sizes. Depending on your background, you may find opportunities in software and technology, life sciences, healthcare, financial services, clean energy, media, aerospace, and professional services. Job availability and compensation vary by role, employer, and location.
Explore openings in major employment centers such as Los Angeles, San Francisco, San Diego, San Jose, Sacramento, and surrounding communities. Listings may include on-site, hybrid, and remote arrangements; review each posting for its work location and requirements.
Use Ladders to focus your search on vetted professional jobs paying $100,000 or more. Review role responsibilities, qualifications, compensation details, and workplace expectations, then apply directly to opportunities that fit your goals. Keep your profile and resume current so employers can better understand your experience.
Senior Analyst, Finance (Medicare, VBC, SQL) - REMOTE
$90K - $110K *
Deliver comprehensive financial analysis and support for Medicare operations across multiple markets, driving insights and collaboration to enhance performance, forecasting, and reporting, ensuring ef...
3 weeks ago
Senior Manager, Medical Imaging
$178K - $230K *
Elevate your impact by managing radiologic services while ensuring patient care, safety, and regulatory compliance. Lead a dedicated team to implement protocols, enhance operational efficiency, and fo...
Reposted 5 days ago
Director of Patient Navigation
$131K - $198K *
Design and implement oncology nurse navigation standards across multiple regions, ensuring seamless patient care coordination and performance improvement. Collaborate with teams to enhance patient exp...
1 week ago
$111K - $167K *
Empower your career by leading IT systems development, implementation, and maintenance. Oversee complex networks, ensure security, and drive automation, all while collaborating to enhance operational...
Reposted 2 weeks ago
$91K - $118K *
Transform project execution by leading teams and managing resources to drive success. Collaborate with stakeholders, monitor risks, and ensure alignment to exceed project goals within established para...
Reposted 4 days ago
Senior Financial Business Systems Analyst
$130K - $169K *
Accelerate healthcare efficiency by managing business and financial systems. Collaborate with teams to implement solutions, optimize processes, and ensure seamless integration of applications for impr...
3 days ago
Senior Financial Business Systems Analyst
$130K - $169K *
Lead the implementation and support of financial systems in healthcare, ensuring efficient operations and high-quality patient care. Collaborate with teams to address complex issues, optimize systems...
3 days ago
$176K - $230K *
Lead the charge in transforming healthcare through data-driven solutions. As a Senior Data Scientist, you'll spearhead projects that enhance patient outcomes, leveraging your expertise to align data s...
3 weeks ago
Business Development Representative
$82K - $102K *
Engage with healthcare professionals to expand referral networks, enhance service visibility, and streamline admissions. Collaborate with key stakeholders to foster relationships and drive growth in c...
2 weeks ago
Senior Application Analyst - ERP
$110K - $130K *
Join us to drive ERP excellence as a Senior Applications Analyst, focusing on JD Edwards EnterpriseOne. Lead complex support, configuration, and modernization efforts across Finance and Supply Chain...
1 week ago
Associate Director, Clinical Process Engineer
$150K - $180K *
Lead the evolution of clinical process engineering, establishing methodologies and governance to ensure scalable, inspection-ready processes across Clinical Development Operations, while advising seni...
4 days ago
$80K - $92K *
Elevate sustainability efforts by managing data tracking, coordinating LEED initiatives, and supporting environmental compliance. Collaborate with stakeholders to optimize practices, ensuring building...
3 weeks ago
Registered Nurse Case Manager Level 2: Home Health
$140K - $160K *
Shape exceptional patient care by developing and overseeing comprehensive home health plans, ensuring high-quality services while leading a dedicated nursing team in an empowering environment that pri...
Reposted 1 week ago
Sr. Analyst, Guaranteed Investments Contracts
$110K - $115K *
Lead the management of Guaranteed Investment Contracts, executing deals and analyzing risk while collaborating with cross-functional teams to deliver bespoke investment solutions and enhance business...
1 week ago
$99K - $127K *
Champion compassionate home health care by coordinating care plans and empowering participants to live independently. Collaborate with an interdisciplinary team to deliver skilled nursing services in...
6 days ago
Senior Manager, Trial Surveillance & Analytics (Hybrid)
$145K - $175K *
Innovate data-driven solutions in clinical trial surveillance, integrating analytics and AI to enhance patient safety and efficacy insights. Collaborate with cross-functional teams to design, build, a...
1 week ago
Senior Nurse Director, Regional Maternal Child Health Services (MCH)
$260K - $300K *
Drive strategic patient care initiatives across multiple locations, enhancing safety and efficiency. Oversee operations, manage resources, and cultivate partnerships to improve outcomes, while maintai...
Reposted 5 days ago
Director, CMS & HHS Business Development
$182K - $250K *
Champion market development strategies to enhance our presence in CMS and HHS. Leverage your expertise to build relationships, identify opportunities, and drive impactful outcomes in federal health IT...
2 weeks ago
Lead AI and Data Solution Engineer
$200K - $215K *
Drive the design and deployment of innovative data and AI solutions, leveraging expertise in LLMs, agentic AI, and cloud technologies to enhance business value and ensure compliance with industry stan...
2 weeks ago
$100K - $120K *
Join a team that analyzes credit policies and develops strategies to enhance lending effectiveness, utilizes data analytics for risk management, and collaborates with stakeholders to drive impactful d...
Reposted 1 week ago
Nurse Manager II, Hospital Operating Room
$213K - $246K *
Redefine patient care delivery as you lead teams in several clinical areas, ensuring compliance and optimal patient outcomes. Collaborate with multidisciplinary teams to drive operational improvements...
Reposted 5 days ago
Director of Compliance Registered Nurse RN
$98K - $143K *
Drive compliance excellence by leading clinical operations in infection control, risk management, and regulatory adherence. Utilize your expertise to enhance patient safety and quality management in a...
1 week ago
Workday Healthcare Financial Implementation Consultant
$140K - $210K *
Partner with us to drive innovative financial solutions in the healthcare sector. Leverage your Workday expertise for impactful implementations, collaborating closely with teams to transform operation...
Reposted 5 days ago
$170K - $210K *
Shape the future of data engineering by owning our core infrastructure and driving the technical direction of data platforms. Collaborate across teams to ensure best practices in data modeling, pipeli...
4 weeks ago
Staff Research Associate III (Ethnographer)
$70K - $93K *
Support innovative research in music and dementia by conducting in-home ethnographic studies, managing participant interactions, and ensuring data integrity. Collaborate with a diverse team to enhance...
2 weeks ago
What types of $100,000+ jobs can I find in California?
California listings may include senior and specialized roles in technology, healthcare, finance, life sciences, entertainment, clean energy, manufacturing, and other fields. Available positions depend on current employer needs.
Where in California can I search for jobs?
You can explore opportunities across the state, including major employment hubs such as Los Angeles, San Francisco, San Diego, San Jose, and Sacramento. Check each posting for its specific location and work arrangement.
Are all jobs on this page guaranteed to pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for compensation information and details, since pay can vary by position and employer.
Can I find remote or hybrid California jobs?
Some listings may offer remote or hybrid work, while others require on-site work. The job posting provides the employer’s location and work arrangement requirements.
How can I improve my California job search?
Narrow your search by role, location, industry, and work arrangement. Keep your resume and profile updated, and carefully compare each opportunity’s qualifications and compensation details.