Explore $100K+ Jobs in Oklahoma

Find professional opportunities across Oklahoma with salaries of $100,000 or more. Ladders features vetted jobs for experienced candidates seeking leadership, specialized, and other high-paying roles. Explore openings in Oklahoma City, Tulsa, and communities throughout the state, and discover opportunities that match your skills and career goals.

High-Paying Careers Across Oklahoma

Oklahoma’s economy includes established industries such as energy, aerospace, healthcare, manufacturing, finance, and technology. Employers may seek experienced professionals for roles in operations, engineering, corporate leadership, sales, information technology, and clinical or administrative management. Available positions and compensation vary by employer, location, experience, and specialization.

Find the Right Role for Your Experience

Use Ladders to explore vetted professional job listings and focus your search on roles with compensation of $100,000 or more. Review each posting for its responsibilities, qualifications, location, and compensation details. Set up a strong profile and tailor your resume to highlight measurable results, relevant expertise, and leadership experience.

Search Oklahoma Jobs on Ladders

Whether you’re considering a move to Oklahoma or looking to advance your career close to home, browse current high-paying opportunities and apply to positions that fit your background. New listings may appear as employers’ needs change, so check back regularly for the latest Oklahoma jobs.

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Gastroenterologist Jobs in Oklahoma

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$125K - $140K *

Optimize your career by managing enterprise-wide database environments, ensuring high availability, executing disaster recovery strategies, and supporting critical operations in a dynamic SaaS ecosyst...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$150K *

Drive new business growth by owning the full sales cycle in SMB and Mid-Market segments. Build relationships, strategize territory plans, and deliver compelling proposals to meet client needs while ex...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$188K - $225K *

Advance your career by advising top-tier technology leaders globally, guiding them in overcoming challenges, implementing strategies, and leveraging insights to drive transformative change and organiz...

RemoteRemote

Reposted today

  •   15+ years exp.  •   Business Services

$120K - $190K *

Empower project success by managing sales opportunities, creating piping layouts, and fostering strong customer relationships. Utilize your engineering expertise to navigate complex situations and del...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$170K - $180K *

Elevate your career by shaping market strategies for a thriving POS solution. Lead a high-performing team to drive adoption and growth, while influencing product direction in a dynamic, collaborative...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$150K - $180K *

Drive product strategy and execution for a critical portfolio area, leading cross-functional teams to transform user insights into impactful software solutions while mentoring others and shaping platf...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$150K - $180K *

Elevate client relationships by managing strategic Tier 1 accounts, driving revenue growth, and ensuring customer satisfaction. Collaborate cross-functionally to develop account strategies and deliver...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Enterprise Technology

$110K *

Join a team that's driving revenue growth in the restaurant and hospitality sectors. Leverage your software sales experience to build relationships and engage with senior decision-makers, delivering s...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$183K - $228K *

Drive strategic financial insights as a key partner to the go-to-market teams, owning revenue forecasts and investment economics. Collaborate with leadership to shape long-term growth strategies and e...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$140K - $175K *

Drive operational excellence by leading strategic initiatives and managing a team to enhance Care Operations. Transform high-level strategies into scalable systems that improve care delivery and patie...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Elevate your career by leading teams in designing and managing fiber networks. Oversee project lifecycles, ensure quality and safety, and coordinate with stakeholders to drive efficiency and meet busi...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$92K - $167K *

Drive compliance and contractor support in contracting standards, regulatory adherence, and policy execution. Work collaboratively across departments to provide strategic guidance, ensuring alignment...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Healthcare

$120K *

Partner with us to enhance product knowledge through comprehensive training programs, ensuring effective customer support and the growth of clinical expertise in the field sales organization. Be a cli...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Healthcare

$140K - $170K *

Join a team that's dedicated to advancing tuberculosis (TB) prevention and care. As a senior technical advisor, you'll lead innovative strategies, collaborate with global partners, and enhance TB prog...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Innovate in Business Development, driving growth across strategic regions and services. Leverage your expertise to enhance patient care and operational efficiency while building strong relationships i...

Reposted today

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Join a team that's dedicated to enhancing clinical operations through strategic site identification and management. Leverage your expertise to build relationships, track project timelines, and contrib...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Champion seamless data integration across IT systems by leading complex projects, troubleshooting issues, and optimizing performance. Leverage your expertise in integration technologies to ensure data...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Empower decision-making by utilizing data-driven insights to enhance operations, supporting growth through statistical modeling and AI techniques while maintaining compliance in a complex regulatory e...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $160K *

Lead all HR functions in a dynamic biotech environment, enhancing employee experience and compliance while driving scalable processes and supporting leadership. Engage with teams to foster growth and...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$79K - $114K *

Grow your career with us by providing exceptional acute care physical therapy, assessing and treating patients, collaborating with teams, and promoting quality improvement in a dynamic healthcare envi...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$191K - $238K *

Shape the future of oncology by leading medical strategy for prostate cancer projects. Collaborate with cross-functional teams to drive scientific communication and strategic initiatives, ensuring ali...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$200K - $280K *

Help us architect a robust regulatory framework that empowers GPs to thrive in complex financial markets. You will lead compliance initiatives, ensuring operational integrity and strategic alignment w...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$250K - $300K *

Lead a dynamic team of radiologists in a remote setting, managing diverse caseloads including inpatient and outpatient cases. Enjoy a supportive culture with growth opportunities and a compensation mo...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$215K - $250K *

Pioneer your career by leading a dynamic sales team focused on Labor and Public Sector markets. Drive growth, mentor talent, and execute strategic initiatives to exceed revenue goals while building im...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Drive the future of AI & Analytics by leading client relationships, providing strategic guidance, and delivering innovative solutions. Leverage your expertise to enhance service delivery and ensure al...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs can I find in Oklahoma?question toggle

    Listings may include professional and leadership roles in areas such as energy, aerospace, healthcare, technology, manufacturing, finance, engineering, operations, and sales. Job availability and compensation vary.

  • Which Oklahoma cities have high-paying job opportunities?question toggle

    Opportunities may be available in Oklahoma City, Tulsa, and other communities across the state. Check each listing for its location and whether remote or hybrid work is offered.

  • Does Ladders list jobs that pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with compensation of $100,000 or more. Review individual postings for specific salary information and qualifications.

  • How can I find Oklahoma jobs that fit my experience?question toggle

    Search current listings and compare each role’s requirements, responsibilities, location, and compensation. Tailor your resume to emphasize relevant skills, accomplishments, and experience.