Explore $100K+ Jobs in Oklahoma

Find professional opportunities across Oklahoma with salaries of $100,000 or more. Ladders features vetted jobs for experienced candidates seeking leadership, specialized, and other high-paying roles. Explore openings in Oklahoma City, Tulsa, and communities throughout the state, and discover opportunities that match your skills and career goals.

High-Paying Careers Across Oklahoma

Oklahoma’s economy includes established industries such as energy, aerospace, healthcare, manufacturing, finance, and technology. Employers may seek experienced professionals for roles in operations, engineering, corporate leadership, sales, information technology, and clinical or administrative management. Available positions and compensation vary by employer, location, experience, and specialization.

Find the Right Role for Your Experience

Use Ladders to explore vetted professional job listings and focus your search on roles with compensation of $100,000 or more. Review each posting for its responsibilities, qualifications, location, and compensation details. Set up a strong profile and tailor your resume to highlight measurable results, relevant expertise, and leadership experience.

Search Oklahoma Jobs on Ladders

Whether you’re considering a move to Oklahoma or looking to advance your career close to home, browse current high-paying opportunities and apply to positions that fit your background. New listings may appear as employers’ needs change, so check back regularly for the latest Oklahoma jobs.

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$124K - $135K *

Shape impactful training programs for Field Access teams, enhancing access and reimbursement capabilities across therapeutic areas. Collaborate with stakeholders to ensure compliance and relevance, fo...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $200K *

Lead high-impact client delivery operations, ensuring quality execution and resource optimization across diverse projects. Collaborate with cross-functional teams to drive performance and enhance cust...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$88K - $140K *

Drive the development of predictive analytics models to enhance digital assessment operations, collaborating across teams to optimize decision-making and reduce costs while supporting strategic goals...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Transform eDiscovery management by driving operational excellence, ensuring timely project delivery, and enhancing workflow efficiency. Collaborate with stakeholders to uphold quality standards and fo...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$185K - $256K *

Join a team that's redefining CMC strategies in life sciences. You'll engage with industry leaders, drive software adoption, and shape market narratives to enhance product lifecycle management and ope...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$210K - $250K *

Drive clinical informatics initiatives, optimizing EHR systems and enhancing patient care through collaboration with diverse teams. Lead continuous improvement efforts and advance interoperability acr...

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$145K - $190K *

Lead the charge in designing and optimizing scalable data pipelines using Azure, PySpark, and Airflow. Collaborate with teams to ensure data quality and performance while mentoring engineers and drivi...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Analyze cloud cost optimization challenges, partnering with customers to enhance FinOps services. Work closely with sales and product teams, utilizing deep Azure expertise to drive actionable insights...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$75K - $90K *

Elevate clinical demand for Inogen therapy by engaging physicians and care teams, driving referrals, and educating on best practices within the Oklahoma City/St. Louis market. This role requires strat...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$142K - $177K *

Lead legal initiatives by drafting documents, managing records, and providing counsel. Collaborate with executives to shape organizational direction while ensuring compliance and supporting continuous...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$135K - $160K *

Lead the charge in defining user experience strategy, managing a multi-disciplinary design team to deliver innovative, user-centered digital products while fostering collaboration and high-impact desi...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$90K - $110K *

Champion the future of nursing services by leading staff, optimizing care delivery, and ensuring compliance with standards. Collaborate with clinical leaders to enhance patient outcomes and operationa...

5 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$166K - $244K *

Join a dynamic team to lead the Employer PMO, driving strategic program delivery and cross-functional alignment while enhancing operational efficiency and leveraging modern tools for impactful outcome...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $180K *

Lead the charge in delivering enterprise-level growth programs by ensuring alignment across all functions, driving planning and execution adherence, and managing complex initiatives for timely product...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$80K - $95K *

Drive operational excellence by developing and maintaining standards, ensuring consistency across markets, and collaborating with cross-functional teams to enhance processes and documentation for opti...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Lead the onboarding function for diverse customer segments, managing a team to ensure a seamless transition from contract to go-live. Collaborate cross-functionally to enhance processes and drive cust...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$190K - $225K *

Empower commercial strategies by building relationships with key thought leaders in rare neurological diseases, capturing insights to inform brand development and launch planning, and ensuring impactf...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Join a dynamic team as a senior leader, driving client relationships and revenue growth in lead-generation sectors. You'll manage a diverse portfolio, ensuring lead quality and speed while leveraging...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$95K - $140K *

Drive impactful financial due diligence for M&A activities, collaborating with clients and executives to assess enterprise value and risks. Join a high-performing team dedicated to excellence in deal...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Legal & Accounting

$150K - $180K *

Manage financial planning and performance analysis for the GTM organization, partnering with leadership across Sales, Marketing, and Customer Success to drive revenue growth and profitability through...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$90K - $120K *

Optimize operational excellence in healthcare IT by managing production support, driving issue resolution, and ensuring timely reporting for customer-facing technology delivery...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$92K - $124K *

Partner with us to enhance legal operations and implement eDiscovery processes. You'll lead customer data privacy initiatives, improving cross-functional collaboration and response strategies for comp...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$66K - $124K *

Empower client success by managing large accounts, ensuring exceptional service, and developing tailored insurance solutions. Collaborate with teams to drive client initiatives and foster long-term re...

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$140K - $160K *

Engage with senior leaders and drive enterprise sales in the scientific sector. Own pipeline generation and foster relationships while leading complex sales cycles. Shape commercial proposals that bri...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Staffing

$177K - $243K *

Advance your career by leading a global compensation function, shaping strategies, and building a high-performing team. Collaborate with key stakeholders to drive compensation programs that align with...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs can I find in Oklahoma?question toggle

    Listings may include professional and leadership roles in areas such as energy, aerospace, healthcare, technology, manufacturing, finance, engineering, operations, and sales. Job availability and compensation vary.

  • Which Oklahoma cities have high-paying job opportunities?question toggle

    Opportunities may be available in Oklahoma City, Tulsa, and other communities across the state. Check each listing for its location and whether remote or hybrid work is offered.

  • Does Ladders list jobs that pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with compensation of $100,000 or more. Review individual postings for specific salary information and qualifications.

  • How can I find Oklahoma jobs that fit my experience?question toggle

    Search current listings and compare each role’s requirements, responsibilities, location, and compensation. Tailor your resume to emphasize relevant skills, accomplishments, and experience.