Explore $100K+ Jobs in Oklahoma

Find professional opportunities across Oklahoma with salaries of $100,000 or more. Ladders features vetted jobs for experienced candidates seeking leadership, specialized, and other high-paying roles. Explore openings in Oklahoma City, Tulsa, and communities throughout the state, and discover opportunities that match your skills and career goals.

High-Paying Careers Across Oklahoma

Oklahoma’s economy includes established industries such as energy, aerospace, healthcare, manufacturing, finance, and technology. Employers may seek experienced professionals for roles in operations, engineering, corporate leadership, sales, information technology, and clinical or administrative management. Available positions and compensation vary by employer, location, experience, and specialization.

Find the Right Role for Your Experience

Use Ladders to explore vetted professional job listings and focus your search on roles with compensation of $100,000 or more. Review each posting for its responsibilities, qualifications, location, and compensation details. Set up a strong profile and tailor your resume to highlight measurable results, relevant expertise, and leadership experience.

Search Oklahoma Jobs on Ladders

Whether you’re considering a move to Oklahoma or looking to advance your career close to home, browse current high-paying opportunities and apply to positions that fit your background. New listings may appear as employers’ needs change, so check back regularly for the latest Oklahoma jobs.

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$206K - $277K *

Champion clinical trial success by leading operations and financial oversight for early-phase oncology studies. Drive process improvements and ensure compliance while collaborating with cross-function...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Drive the future of revenue accounting by ensuring accurate recognition and compliance with ASC 606. Collaborate cross-functionally to streamline processes, support complex deals, and maintain audit r...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$200K - $232K *

Unlock potential by leading legal reviews for promotional and medical materials. Collaborate across teams to ensure compliance and provide practical guidance in a fast-paced environment, supporting pr...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$112K - $180K *

Lead the evolution of revenue forecasting and lending portfolio planning, enhancing financial models and insights. Collaborate across functions to drive strategic analysis and improve decision-making...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $120K *

Lead the charge in optimizing purchasing strategies and supplier relationships, ensuring cost efficiencies and compliance while collaborating with the Division Leadership Team to enhance operational p...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$173K - $272K *

Champion the future of digital tech transfer and knowledge management by leading a dynamic team to enhance manufacturing capabilities. Drive strategic initiatives that integrate data-driven solutions...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Optimize the promotional review process by coordinating cross-functional workflows, ensuring compliance, and facilitating timely approvals of marketing materials. Collaborate with internal and externa...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$349K - $396K *

Lead the charge in driving national growth strategies for enterprise employers, managing a top-performing sales team focused on Fortune 500 engagements, overseeing the acquisition lifecycle, and ensur...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$67K - $101K *

Innovate your sales career by driving revenue growth and building lasting customer relationships. Own your territory, manage the full sales cycle, and collaborate with teams to accelerate deals and en...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Lead the charge in Epic solutions delivery by providing expert support, managing projects, and mentoring team members. Shape the future of healthcare IT by aligning technical teams with stakeholder ne...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$112K - $140K *

Transform your career by leading claims advocacy efforts, managing complex coverage issues, and providing expert guidance to brokers and clients. Collaborate with teams to ensure positive outcomes and...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$127K - $165K *

Unlock potential by leading regulatory strategies for innovative medical devices. Collaborate with teams to ensure compliance, execute FDA submissions, manage project timelines, and establish processe...

RemoteRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Healthcare

$225K - $275K *

Lead the charge in driving shopper growth, transforming casual users into engaged buyers through innovative acquisition and retention strategies while overseeing a dedicated team from day one...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Consumer Technology

$111K - $145K *

Lead transformative IT projects from inception to completion, ensuring timely delivery and budget adherence. Collaborate across departments to translate business needs into actionable plans while mana...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$120K - $177K *

Lead and develop a distributed team of Project Coordinators, enhancing operational health and governance across complex automation deployments while driving continuous improvement and collaboration wi...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Accelerate your career by overseeing manufacturing processes and driving operational excellence. Collaborate with leadership to enhance productivity, implement improvements, and foster a high-performa...

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K *

Unlock potential by driving enterprise account strategies and engaging technical leaders. Collaborate with AEs to create meaningful outreach and build a pipeline that converts, focusing on quality int...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$105K - $163K *

Champion client success by leading project teams to deliver high-quality card processing solutions. Drive enhancements, manage complex implementations, and ensure client satisfaction through effective...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$95K - $123K *

Lead the charge in pharmaceutical meetings operations, driving client partnerships and operational excellence while navigating compliance. Shape processes and enhance stakeholder engagement to deliver...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Transportation

$120K - $150K *

Elevate your career by leading clinical trial management teams, ensuring quality and compliance in monitoring strategies. Collaborate with cross-functional teams to optimize clinical operations and dr...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$147K - $217K *

Lead transformative analytics initiatives in life sciences, driving innovation and client success. Mentor teams, enhance measurement standards, and collaborate cross-functionally to deliver actionable...

RemoteRemote

3 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$108K - $149K *

Drive revenue operations excellence by enhancing MSSP processes and systems. Collaborate with cross-functional teams to operationalize strategies, streamline workflows, and support partner lifecycle m...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$156K - $235K *

Transform the healthcare sales landscape by leading a dynamic team to drive revenue and margin growth. Leverage your expertise to achieve commercial objectives while fostering strong relationships and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$80K - $95K *

Drive quality excellence by managing a comprehensive Quality Management System, leading teams to enhance processes, and fostering strong customer and supplier relationships to meet business objectives...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$180K - $220K *

Lead the charge in developing clinical content strategies and overseeing teams within the market access practice. Drive innovation, enhance client strategies, and ensure high standards in service deli...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs can I find in Oklahoma?question toggle

    Listings may include professional and leadership roles in areas such as energy, aerospace, healthcare, technology, manufacturing, finance, engineering, operations, and sales. Job availability and compensation vary.

  • Which Oklahoma cities have high-paying job opportunities?question toggle

    Opportunities may be available in Oklahoma City, Tulsa, and other communities across the state. Check each listing for its location and whether remote or hybrid work is offered.

  • Does Ladders list jobs that pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with compensation of $100,000 or more. Review individual postings for specific salary information and qualifications.

  • How can I find Oklahoma jobs that fit my experience?question toggle

    Search current listings and compare each role’s requirements, responsibilities, location, and compensation. Tailor your resume to emphasize relevant skills, accomplishments, and experience.