Explore $100K+ Jobs in Alabama

Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.

Where to Find Professional Jobs in Alabama

Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.

Industries and Roles

High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.

Find the Right Alabama Opportunity

Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.

Advance Your Career in Alabama

Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.

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$162K - $243K *

Join a team that's dedicated to advancing clinical trials through strategic oversight and collaboration. Lead project management efforts globally, ensuring quality, cost, and timeline objectives are m...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$78K - $106K *

Transform client payment policies by ensuring accuracy and compliance. Engage with internal and external teams to manage medical policy updates, conduct analyses, and enhance client relationships whil...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$235K - $270K *

Elevate your career by leading access strategy across the Mountain and Pacific territories. Drive relationships with regional payers and ensure launch readiness for rare disease products while collabo...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $140K *

Pioneer GxP compliance in digital quality management, ensuring software and AI products meet regulatory standards. Collaborate with stakeholders to enhance quality processes and support audits, drivin...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$105K - $150K *

Transform healthcare insights by leading client engagements with real-world data. Drive business development and project delivery while building long-term client relationships in a dynamic, hybrid wor...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $120K *

Unlock potential by leading day-to-day accounting operations, ensuring accurate financial reporting, and driving process improvements in a dynamic e-commerce environment. Collaborate across teams to e...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$250K - $286K *

Shape the future of sales by leading a dynamic team to drive new business, refine strategies, and enhance customer experiences in a fast-paced SaaS environment, while mentoring leaders and achieving a...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$65K - $109K *

Partner with us to foster strategic relationships, optimize account performance, and drive engagement with key stakeholders, leveraging your knowledge of healthcare technology to deliver impactful sol...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$170K - $210K *

Shape the future of financial reporting by leading SEC compliance and technical accounting. Drive policy development, optimize processes, and collaborate with cross-functional teams to support growth...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$242K - $303K *

Join as the primary privacy leader to manage and enhance an enterprise-wide privacy program while navigating complex regulations. Collaborate across departments to drive compliance, innovation, and ef...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$177K - $221K *

Empower compliance excellence by leading the NSCLC field compliance program. Collaborate with cross-functional teams to identify risks, develop scalable solutions, and ensure adherence to regulations...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$172K - $216K *

Help us drive growth in the utilities sector by leading a high-performing sales team. You'll shape strategies, build relationships, and coach sellers to excel in complex, multi-year deals, ensuring al...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Consumer Technology

$174K - $374K *

Unlock potential by leading medical management initiatives remotely, supporting member needs and optimizing clinical services for optimal care. Leverage your expertise in Orthopedic Spine or Neurosurg...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$115K - $125K *

Drive the development and management of virtual health services, enhancing operational excellence and patient experience while scaling innovative care models across the organization. Lead strategic in...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$160K - $185K *

Transform client value and operational performance by leveraging data-driven insights, financial modeling, and strategic solutions. Collaborate across teams to enhance service delivery and drive measu...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$150K - $206K *

Drive strategic risk management initiatives by leading regulatory audits, enhancing operational processes, and fostering cross-functional collaboration to minimize financial impacts and improve audit...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$119K - $186K *

Lead the negotiation and administration of Branded & Specialty Rx contracts, ensuring alignment with business strategies and stakeholder interests. Collaborate with internal teams to optimize processe...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$74K - $92K *

Empower our channel partner division by managing operational activities, coordinating RFPs, and driving cross-functional collaboration to enhance sales and partner engagement. Your insights will shape...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $156K *

Drive data excellence by leading analytics initiatives, enhancing governance, and integrating systems. Collaborate with leadership to deliver impactful insights and ensure compliance while leveraging...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Staffing

$67K - $199K *

Empower operational excellence by leading provider data governance and attribution processes. Collaborate across departments to ensure data integrity, enhance reporting accuracy, and drive continuous...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$170K - $200K *

Transform your career by leading a high-performing sales team, driving strategic growth, and enhancing client relationships in a dynamic, global environment. Leverage your expertise in IoT solutions t...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Transportation

$119K - $186K *

Lead the charge in shaping a skills-powered talent ecosystem, driving strategy and governance for enterprise skills and talent marketplace initiatives that enhance workforce planning and career growth...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$163K - $297K *

Champion the development and execution of innovative digital product strategies across EMEA, enhancing consumer experiences and driving key performance indicators in a high-growth e-commerce environme...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$115K - $140K *

Shape the future of payroll management by leading certified payroll processing and union remittance. Drive compliance, accuracy, and team development while collaborating across departments to ensure t...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$150K - $180K *

Shape the future of enterprise-scale cybersecurity by leading vulnerability management initiatives. Drive program strategy, enhance client relationships, and mentor teams to achieve measurable risk re...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Alabama?question toggle

    Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.

  • Which Alabama cities have high-paying professional jobs?question toggle

    Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.

  • Are the Alabama jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.

  • How can I find a $100K+ job in Alabama?question toggle

    Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.

  • Do Alabama jobs listed on Ladders require in-person work?question toggle

    Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.