Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$135K - $202K *

Drive product operations excellence by leading cross-functional teams, enhancing AI integration, and optimizing UX design to ensure a seamless product development lifecycle that empowers rapid, high-q...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Join a dynamic team as a senior leader, driving client relationships and revenue growth in lead-generation sectors. You'll manage a diverse portfolio, ensuring lead quality and speed while leveraging...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $145K *

Empower product delivery for a life sciences IoT platform by collaborating with stakeholders and engineering teams. Drive product vision, prioritize features, and ensure successful outcomes through Ag...

Today

  •   5 - 7 years exp.  •   Information Technology

$110K - $150K *

Empower a global workforce by managing IT services, ensuring reliable, secure technology solutions, and enhancing employee experience in a fast-paced SaaS environment. Drive strategic direction while...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Information Technology

$267K - $400K *

Empower our commercial legal function by providing strategic legal guidance on pre-launch and market access initiatives. Collaborate across teams to ensure compliance and support successful product la...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Unlock your potential as a Program Manager, leading federal service contracts and driving operational excellence. Collaborate with teams to ensure quality delivery, financial performance, and customer...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Business Services

$165K - $185K *

Lead the execution of AI-enabled clinical informatics initiatives, focusing on Ambient AI Scribe capabilities. Drive program delivery, align stakeholders, and enhance clinical workflows to improve hea...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$88K - $110K *

Champion the successful delivery of strategic projects, leading cross-functional teams to ensure timely execution and risk management. Drive accountability and foster collaboration to meet development...

2 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$163K - $261K *

Shape the future of electrification services by leading operations across the West U.S. region, driving performance excellence, and managing nationwide digital automation initiatives while advancing r...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$150K - $185K *

Champion the development of enterprise IT Financial Management, enhancing transparency in technology investments and enabling informed decision-making across the organization. Lead cross-functional co...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$230K - $263K *

Lead critical programs that shape scalable products and platforms. Drive collaboration across teams, implement holistic solutions, and manage risk effectively while mentoring your TPM team to achieve...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Manage and lead field-based medical teams, ensuring client delivery and team performance while fostering scientific engagement and program growth. Collaborate with cross-functional teams to achieve st...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $160K *

Drive execution of next-gen robotics programs, leading cross-functional teams to deliver integrated humanoid systems. Ensure successful project management from planning to deployment in a high-impact...

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$83K - $112K *

Support large-scale research initiatives by managing operations, budgets, and partnerships. Oversee project teams, ensure compliance, and contribute to data analysis and publications, driving innovati...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$70K - $105K *

Manage and oversee multiple medical communications projects, ensuring timely delivery and operational excellence while collaborating with cross-functional teams and clients to drive impactful healthca...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$175K - $200K *

Lead the charge in developing integrated media strategies and client partnerships across pharmaceutical and life sciences accounts, driving business growth and ensuring exceptional delivery and client...

United StatesRemote

5 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$147K - $172K *

Transform contract development and oversight for outsourced construction projects. Lead a dynamic team in managing compliance, risk, and efficiency while fostering strong internal and external relatio...

3 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$115K - $150K *

Join a team that's dedicated to guiding recovery efforts post-disaster. Lead a multi-disciplinary team, leveraging your expertise in FEMA programs to support local governments through complex recovery...

RemoteRemote

Yesterday

  •   Less than 5 years exp.  •   Business Services

$110K - $130K *

Join a team that's driving transformative change across the university. Lead initiatives that enhance organizational effectiveness, foster collaboration, and promote a culture of learning and innovati...

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Lead the development and management of inspection programs, ensuring compliance and continuous improvement within the Command, Control, Communications, and Battle Management Division, while supporting...

Yesterday

  •   11 - 15 years exp.  •   Information Technology

$110K - $130K *

Shape the future of defense acquisition by leading program management efforts, ensuring compliance and performance across multi-faceted projects for advanced military systems while driving collaborati...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Lead strategic acquisition and program management for C3BM, enhancing USAF and Coalition capabilities. Drive critical initiatives within Air Force acquisition lifecycle, ensuring program execution ali...

4 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$100K - $122K *

Take ownership of financial planning and analysis for G&A expenses, driving insights and reporting for senior leadership. Collaborate with teams to enhance budgeting, forecasting, and variance analysi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$140K - $150K *

Analyze and optimize customer journeys from signup to paid conversion, leveraging data insights to drive growth strategies. Collaborate across teams to enhance product decisions and influence market p...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $130K *

Contribute to project success by coordinating activities, maintaining documentation, and supporting delivery. Collaborate with experienced teams to enhance your project management skills and manage co...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.