Explore $100K+ Jobs in Illinois

Find high-paying career opportunities across Illinois with Ladders. Browse vetted professional jobs offering salaries of $100,000 or more, from openings in Chicago to roles in cities and communities throughout the state. Whether you’re ready to take the next step in your career or explore a new industry, discover Illinois positions that match your experience and goals.

Career Opportunities Across Illinois

Illinois offers a broad range of professional opportunities, with a concentration of employers and roles in the Chicago area and opportunities across the rest of the state. Explore positions in fields such as finance, technology, healthcare, manufacturing, consulting, and business leadership. Available roles and compensation vary by employer, location, and experience.

Find a Role That Fits Your Experience

Use Ladders to explore professional openings with salaries of $100,000 or more. Review job details, compare opportunities, and focus your search on the locations, industries, and responsibilities that align with your career plans. Check listings for requirements, work arrangements, and compensation details.

Advance Your Career in Illinois

Start your search for a high-paying job in Illinois by browsing current listings and applying to roles that fit your qualifications. New opportunities can become available over time, so check back regularly to find the latest vetted professional jobs on Ladders.

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$125K - $150K *

Unlock potential by driving client success through expert system configuration, data analysis, and consultative training. Ensure timely project delivery while enhancing user experience and satisfactio...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$150K - $180K *

Join a team that's redefining scientific data management in drug discovery. Lead the scientific data team, bridging scientists and engineers to ensure data integrity, quality, and innovative solutions...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$70K - $140K *

Lead the charge in enhancing our Partner ecosystem by managing relationships and driving growth initiatives. Oversee onboarding, operations, and support for System Integrators while implementing autom...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Lead technology programs and strategic initiatives, managing project scope, delivery, and stakeholder engagement. Collaborate across teams to drive successful client outcomes in financial services and...

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$181K - $225K *

Lead the charge in advancing scientific operations within a dynamic team, driving global lab relationships and supporting complex clinical studies. Collaborate across functions to ensure strategic, op...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$150K - $180K *

Unlock new opportunities as you drive business growth in the life sciences sector. Focus on building relationships and matching client needs with innovative solutions in commercial consulting, brand c...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $145K *

Accelerate your career by leading the operational setup and management of a dynamic accessory line. Drive supply chain efficiency, optimize distribution strategies, and enhance customer service while...

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$125K - $145K *

Lead the operational setup and management of a shower accessory business, developing scalable supply chain strategies, optimizing distribution networks, and ensuring exceptional customer service and o...

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$85K - $100K *

Transform industrial construction projects by ensuring safety, quality, and efficiency. Collaborate with teams to meet strategic objectives while managing scope, budget, and schedule in a refinery set...

2 weeks ago

  •   Less than 5 years exp.  •   Staffing

$150K - $180K *

Reimagine executive compensation strategies by leading comprehensive consulting services for M&A transactions, guiding clients through performance transformations, and mentoring teams to achieve impac...

4 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $95K *

Lead quality management initiatives to enhance pediatric services, ensuring compliance with regulatory standards. Drive continuous improvement through audits, training, and collaboration with clinical...

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$144K - $214K *

Champion continuous improvement initiatives across multiple plants, driving operational excellence and efficiency. Collaborate with leadership to develop strategies that enhance productivity and foste...

2 weeks ago

  •   8 - 10 years exp.  •   Food & Beverages

$183K - $215K *

Shape the future of North American inland transportation by leading product strategy and development. Collaborate with cross-functional teams to deliver actionable insights and drive market success in...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Empower your career by leading diverse industrial and infrastructure projects. Collaborate with multidisciplinary teams, enhance client relationships, and drive project success while deepening your en...

6 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Help us transform your technical expertise into project leadership. Collaborate on diverse industrial and infrastructure projects, enhancing your skills in management, client relations, and multidisci...

6 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Join a team that's shaping the future of industrial and infrastructure projects. Leverage your engineering expertise to lead multidisciplinary teams, enhance project delivery, and build lasting client...

6 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$120K - $145K *

Discover a dynamic role leading a high-performing data center operations team, driving strategic improvements and ensuring optimal performance across a geographically dispersed infrastructure in a fas...

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$188K - $245K *

Drive innovative UX design strategies in clinical settings, leading a talented team to enhance decision support and care coordination. Collaborate across functions to integrate AI and elevate user exp...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$128K - $208K *

Lead the architectural vision for a cutting-edge digital platform, ensuring robust data management and integration. Collaborate with cross-functional teams to deliver scalable solutions that meet busi...

5 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$120K - $150K *

Drive full-cycle sales for global clinical operations, fostering client relationships and developing strategic plans for service growth in alignment with company objectives...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Drive enterprise growth by engaging top health system executives, transforming clinical outcomes through innovative solutions, and building strategic partnerships to expand market presence and adoptio...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Shape the future of HR in a dynamic manufacturing environment. Drive talent acquisition, enhance employee engagement, and develop leadership capabilities while ensuring compliance and fostering a high...

4 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Drive organizational success by leading HR initiatives in a dynamic manufacturing environment. Oversee talent acquisition, employee engagement, and development programs to enhance workforce capabiliti...

5 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$88K - $105K *

Drive capacity planning excellence by analyzing optimization solutions and overseeing shipment assignments. Ensure effective market planning, maximize driver utilization, and meet customer service req...

1 week ago

  •   Less than 5 years exp.  •   Transportation

$112K - $171K *

Drive the success of transportation projects by managing traffic studies and engineering initiatives. Collaborate with clients and guide junior staff while ensuring project delivery meets budget and t...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Illinois?question toggle

    Illinois listings may include professional and leadership roles in areas such as finance, technology, healthcare, manufacturing, consulting, and business operations. Job availability and qualifications vary by employer.

  • Are there high-paying jobs outside Chicago?question toggle

    Yes. While many opportunities are based in the Chicago area, listings may also be available in other Illinois cities and communities. Search by location to explore current openings.

  • How can I find Illinois jobs that pay $100,000 or more?question toggle

    Browse Illinois listings on Ladders and review each job’s salary information, qualifications, location, and work arrangement. Listings feature vetted professional opportunities with salaries of $100,000 or more.

  • Do Illinois job listings include remote or hybrid roles?question toggle

    Some listings may offer remote or hybrid work, depending on the employer and position. Check each job description for the specific work arrangement.