Explore Director, Clinical Science opportunities on Ladders, where experienced professionals can find vetted jobs paying $100,000 or more. Directors in clinical science help shape the development of new therapies by guiding clinical research strategy, interpreting evidence, and leading teams through complex studies.
Directors of Clinical Science provide scientific leadership across clinical development programs. They may contribute to study design and protocols, assess clinical data, support regulatory submissions, and work with medical, statistical, regulatory, and operational teams to advance trials. Responsibilities vary by employer, therapeutic area, and stage of development.
Employers commonly seek substantial clinical research or drug-development experience, strong scientific judgment, and the ability to communicate complex findings clearly. Leadership, cross-functional collaboration, familiarity with clinical trial processes, and experience interpreting clinical data are valuable. Requirements may include an advanced degree in a relevant scientific or medical field, depending on the position.
Director-level clinical science roles can be found at biotechnology and pharmaceutical companies, clinical research organizations, and other healthcare organizations. Opportunities may focus on a specific therapeutic area, clinical program, or phase of development. Review each listing for details about scope, qualifications, location, and compensation.
Browse vetted Director, Clinical Science job listings on Ladders and discover opportunities with salaries of $100,000 or more. Use job details to compare roles and identify positions that align with your experience and career goals.
$165K - $170K *
Lead process development initiatives to optimize and scale robust manufacturing processes for solid oral dosage forms, ensuring compliance and efficiency while mentoring junior staff and collaborating...
Today
Senior Clinical Research Associate - CNS
$95K - $115K *
Oversee clinical trial execution, ensuring compliance and data integrity while collaborating with investigative sites. Manage project issues and strive for process improvements to enhance the quality...
1 month ago
$225K - $262K *
Oversee the quality management system, ensuring compliance with regulations and driving continuous improvement initiatives. Lead and develop teams responsible for GxP processes and documentation, enab...
1 month ago
Senior Research Associate, DMPK
$106K - $126K *
Manage and develop LC-MS/MS analytical methods to support pharmacokinetic studies and bioanalysis, ensuring lab operations and data integrity in a collaborative environment with a focus on efficiency...
3 weeks ago
Senior Director, Regulatory Affairs
$175K - $210K *
Lead the charge in developing and executing global regulatory strategies for innovative therapeutics. Collaborate with cross-functional teams to navigate regulatory pathways and ensure compliance from...
3 weeks ago
Clinical Research Program Manager, Hybrid
$110K - $130K *
Empower clinical research initiatives by managing a disease-focused portfolio, leading a dedicated team, and ensuring compliance and efficiency in trial operations while fostering collaboration and st...
Today
Clinical Research Program Manager, Hybrid
$110K - $130K *
Manage a clinical research portfolio, leading a dedicated team to drive innovative research. Oversee operations, ensure compliance, and collaborate with stakeholders to enhance program success and eff...
Today
Associate Director, Protein Sciences
$180K - $200K *
Advance our protein sciences initiatives by leading a team of scientists, driving cross-functional collaboration, and overseeing antibody production and purification to support innovative therapeutic...
2 weeks ago
$80K - $95K *
Unlock your potential as a leader in clinical services, enhancing patient care and developing your team. Oversee staff, manage schedules, and foster positive relationships with stakeholders while ensu...
Reposted today
$98K - $102K *
Innovate transformative ABA services for children with autism, leading clinical excellence and mentorship. Drive program development and collaboration with educators and families to enhance individual...
1 week ago
Director, Medical Affairs, GI & Hepatology
$203K - $279K *
Lead the charge in medical affairs for gastroenterology and hepatology, driving strategic initiatives and cross-functional collaboration to enhance patient care and business outcomes throughout the pr...
1 week ago
Global Medical Lead, Neurometabolic
$295K - $380K *
Join a dynamic team as a strategic leader in global medical affairs, driving innovative strategies and evidence generation for neurometabolic diseases. Collaborate cross-functionally to enhance patien...
1 week ago
Director, Statistical Programming, Pharmacometrics
$205K - $341K *
Champion innovation by leading programming strategy and execution across therapeutic areas, enhancing data integration for clinical development while fostering team growth and implementing operational...
3 weeks ago
$160K - $200K *
Lead the strategic vision and operations of the Quality department, ensuring compliance with regulatory standards and client expectations while fostering a culture of excellence and continuous improve...
2 weeks ago
Director or Senior Director of Translational Medicine
$235K - $310K *
Join a team that empowers translational medicine innovation in early-phase oncology, owning strategies from IND-enabling studies to proof of concept. Drive impactful biomarker integration and clinical...
Reposted 2 days ago
Associate Director, Compliance Field Commercialization, Lung
$177K - $221K *
Empower compliance excellence by leading the NSCLC field compliance program. Collaborate with cross-functional teams to identify risks, develop scalable solutions, and ensure adherence to regulations...
1 week ago
Principal Scientist (Scientific Director Level)– Nonclinical Drug Safety
$176K - $277K *
Drive innovative drug discovery by leading nonclinical safety strategies across therapeutic areas while collaborating with cross-functional teams to evaluate therapeutic targets and develop new drug c...
Reposted 1 week ago
Principal Scientist (Scientific Director Level)– Nonclinical Drug Safety
$176K - $277K *
Manage cross-functional teams to define and implement nonclinical drug safety strategies in immunology and oncology, ensuring the successful transition of drug candidates from discovery to regulatory...
Reposted 1 week ago
Principal Scientist (Scientific Director Level)– Nonclinical Drug Safety
$176K - $277K *
Join a team that's dedicated to advancing innovative drug development through collaboration, leadership, and strategic vision in nonclinical safety across multiple therapeutic areas, ensuring patient...
Reposted 1 week ago
Principal Scientist (Scientific Director Level)– Nonclinical Drug Safety
$176K - $277K *
Elevate the discovery landscape as you lead Nonclinical Drug Safety strategies across multiple therapeutic areas. Collaborate cross-functionally to assess risks, define toxicology study strategies, an...
Reposted 1 week ago
Principal Scientist (Scientific Director Level)– Nonclinical Drug Safety
$176K - $277K *
Empower drug discovery by leading strategic nonclinical safety initiatives across therapeutic areas, ensuring optimal risk assessment and collaboration to support innovative medicines that enhance pat...
Reposted 1 week ago
$160K - $200K *
Empower your career by leading the integration of clinical trial operations and SaaS platform development. Drive innovation and efficiency in a collaborative environment, bridging operational workflow...
1 week ago
Associate Director/Director, Molecular Diagnostics
$177K - $250K *
Elevate your career by leading molecular diagnostics analysis and reporting. Drive clinical research, enhance variant prioritization, and mentor a dynamic team in a cutting-edge genomics lab focused o...
2 weeks ago
Manager, Regulatory Affairs (Clinical Labeling)
$110K - $130K *
Take ownership of IMP labeling processes, ensuring compliance with global regulations and quality standards while collaborating cross-functionally to support clinical trial timelines and enhance label...
3 weeks ago
Director, Business Improvement
$150K - $180K *
Drive strategic initiatives and operational excellence across a global portfolio, partnering with leadership to enhance business performance and deliver measurable outcomes in oncology and rare diseas...
Yesterday
What does a Director of Clinical Science do?
A Director of Clinical Science provides scientific leadership for clinical development programs, helping guide study design, evaluate clinical evidence, and collaborate with cross-functional teams. Specific duties depend on the organization and therapeutic area.
What qualifications are typically required for Director, Clinical Science jobs?
Requirements vary, but employers often look for extensive clinical research or drug-development experience, scientific expertise, leadership skills, and the ability to interpret and communicate clinical data. Some roles require an advanced degree in a relevant field.
Where do Directors of Clinical Science work?
They may work for pharmaceutical and biotechnology companies, clinical research organizations, and other healthcare or life sciences organizations.
What salary range can I find for these jobs on Ladders?
Ladders features vetted professional jobs paying $100,000 or more. Check individual listings for the specific compensation range and benefits.
How can I find the right Director, Clinical Science role?
Compare listings by therapeutic area, responsibilities, required experience, location, and compensation. Focus on roles that match your clinical development background and leadership goals.