Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$150K - $180K *

Elevate your career by leading oncology strategy initiatives, developing competitive approaches for awards, and fostering client relationships to enhance business growth in a dynamic, collaborative en...

Toronto, ONIn-Person

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Champion innovative oncology strategies by coordinating pre-award activities, enhancing client relations, and collaborating with global teams to drive successful outcomes in clinical research and busi...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Lead the charge in developing competitive oncology strategies, ensuring client needs are met through collaboration and expertise. Drive business development and enhance client relations while overseei...

Raleigh, NCRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$195K - $215K *

Elevate your career by leading clinical contracts strategy to drive global trials. Collaborate with diverse teams, shape negotiation approaches, and ensure compliance while developing a high-performin...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$195K - $240K *

Oversee all Data Management operations, ensuring compliance and quality in clinical data handling. Lead vendor relationships, manage timelines, and ensure accurate data for regulatory submissions thro...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$225K - $275K *

Elevate healthcare standards by guiding medical policy and coding within a collaborative team. Leverage your expertise to enhance client relationships, improve payment accuracy, and drive strategic in...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$176K - $229K *

Help us lead clinical supplies for trials by managing CSPs, overseeing packaging, and ensuring compliance with industry regulations. Drive budget management and collaborate across teams for uninterrup...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Lead strategic initiatives and operational excellence as the chief executive, ensuring high-quality care and fiscal integrity while fostering community partnerships and collaboration with stakeholders...

Reposted yesterday

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$120K - $150K *

Shape the future of healthcare by leading ambulatory surgical centers, driving operational excellence, and fostering physician partnerships. Oversee strategic growth initiatives while ensuring high-qu...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $200K *

Lead the charge in optimizing clinical operations while driving strategic initiatives, enhancing productivity, and fostering a collaborative culture. Oversee multiple locations and manage teams, ensur...

1 month ago

  •   8 - 10 years exp.  •   Healthcare

$350K - $398K *

Drive impactful clinical trials in ophthalmology with leadership in study design, execution, and biomarker strategy. Collaborate cross-functionally to ensure timely delivery and regulatory compliance...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Shape the future of healthcare by leading clinical operations across 3-5 skilled nursing facilities in eastern South Dakota, ensuring regulatory compliance and quality care while managing multiple tea...

Reposted yesterday

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$115K - $135K *

Transform clinical trial operations by leading a dynamic team to ensure seamless execution of device-based studies, from feasibility to close-out, while driving process improvements and fostering cros...

Boston, MARemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$210K - $260K *

Join a fast-paced team of medical professionals to evaluate and enhance service appropriateness through evidence-based guidelines, impacting quality patient outcomes across multiple specialties while...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Lead the charge in scaling our Physician Partnerships team, enhancing referral workflows and deepening relationships with physician groups. Drive growth through strategic account management and hands...

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$117K - $208K *

Transform clinical operations by leading strategic initiatives, fostering collaboration, and driving progress across departments to enhance healthcare delivery and support executive decision-making...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$255K - $315K *

Unlock potential by leading pharmacovigilance operations, ensuring compliance and safety for late-stage clinical development and commercial launch. Drive strategy, establish scalable systems, and over...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$225K - $309K *

Lead the charge in developing and executing innovative medical strategies for Rare Diseases, collaborating across teams to enhance patient outcomes and align with global initiatives while nurturing ke...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$210K - $250K *

Shape clinical governance and provider education while overseeing medication management and operational efficiency. Collaborate with leadership to enhance patient care and support research initiatives...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Advance your career by overseeing clinical operations and enhancing practice efficiency. Collaborate with leadership to implement strategic initiatives, mentor managers, and drive high-quality service...

Today

  •   8 - 10 years exp.  •   Healthcare

$215K - $240K *

Transform nonclinical operations by leading outsourcing strategies and vendor management for safety studies. Collaborate with cross-functional teams to ensure compliance, quality, and timely delivery...

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$215K - $240K *

Join a team that's redefining nonclinical operations by leading outsourcing strategies and vendor management for safety studies, ensuring compliance and quality while driving innovation in drug develo...

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$229K - $269K *

Optimize data collection and access across EDC/non-EDC sources. Drive compliance, manage vendor relationships, and ensure quality deliverables while contributing to clinical trial data processes and r...

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$300K - $376K *

Lead cross-functional teams in clinical development, ensuring alignment and execution of strategic plans for pre-clinical assets. Drive decision-making and maintain high standards in clinical oversigh...

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$300K - $376K *

Lead the charge in clinical development strategy, guiding cross-functional teams to ensure timely execution of pre-clinical assets while maintaining high scientific standards and stakeholder alignment...

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.