Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$150K - $180K *

Champion exceptional veterinary care while fostering client relationships. Drive patient wellness through diverse case management, including surgery and urgent care, in a supportive environment that v...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$231K - $365K *

Engage in transformative AI delivery management, leading strategic initiatives and fostering high-performing teams to drive impactful solutions and client satisfaction across diverse engagements...

4 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Join a dynamic team as you lead clinical services and empower growth in a supportive environment focused on patient-first therapy and relationship-driven care, fostering an atmosphere of teamwork and...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Join a dedicated team as you lead our Memory Care program, enhancing the lives of seniors through compassionate care and innovative engagement strategies. Oversee compliance, staff training, and progr...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$160K - $189K *

Lead the charge in strategic Quality Operations across commercial and clinical pharmaceutical sectors, ensuring compliance and product quality through oversight of manufacturing and testing partners...

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Champion operational excellence by leading client delivery initiatives, enhancing relationships, and driving strategic growth. Collaborate with diverse teams to ensure successful engagements and excee...

Today

  •   Less than 5 years exp.  •   Information Technology

$130K - $160K *

Join a dynamic team to lead clinical supply chain operations, optimizing planning, logistics, and vendor management for innovative clinical trials. Drive growth by establishing scalable processes and...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$250K - $290K *

Partner with us to support business growth as a Corporate Counsel in the biotech industry. Engage in contract drafting, negotiation, and compliance, collaborating with cross-functional teams in a fast...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$325K - $495K *

Elevate healthcare by leading clinical operations and performance across inpatient settings. Drive quality, safety, and efficiency while fostering collaboration among multidisciplinary teams to enhanc...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$180K - $199K *

Lead the charge in managing CMC activities across development programs, ensuring alignment and execution from preclinical to commercialization. Drive timelines, budgets, and cross-functional collabora...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$183K - $305K *

Oversee and enhance compliance across global genetic data collaborations, managing deliverables and governance while leading a team to ensure accountability and transparency in operations and strategi...

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$183K - $305K *

Take ownership of data governance and compliance across global partnerships, ensuring effective management and reporting of genetic health data initiatives while collaborating cross-functionally with...

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Shape the future of cardiopulmonary practices by leading operations, fostering relationships, and ensuring excellent service while promoting organizational goals and enhancing patient experiences in a...

Reposted yesterday

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$95K - $125K *

Drive clinical operations and growth by leading a high-performing behavioral health team. Oversee quality, compliance, and performance metrics while fostering partnerships and expanding service offeri...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$127K - $155K *

Elevate participant engagement by implementing strategic retention initiatives, analyzing clinical trial data, and collaborating with cross-functional teams to ensure data integrity and minimize dropo...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$192K - $264K *

Oversee the product development lifecycle, leading cross-functional teams to ensure timely and compliant launch of complex diagnostic products, while driving strategic decisions and resolving interdep...

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$139K - $232K *

Champion drug development by leading cross-functional teams to optimize project strategies, manage risks, and ensure timely delivery of critical milestones in a complex life sciences environment...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $110K *

Empower clinical teams to deliver high-quality, evidence-based ABA therapy. Lead and mentor professionals while collaborating across functions to enhance client care and support growth in a compassion...

Today

  •   Less than 5 years exp.  •   Healthcare

$100K - $110K *

Empower clinical teams to deliver high-quality, evidence-based ABA therapy. Lead and mentor professionals while collaborating across functions to enhance client care and support growth in a compassion...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Champion patient-centered care by leading a clinical team to enhance quality, ensure effective provider support, and drive strategic healthcare initiatives. Focus on mentoring and implementing value-b...

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$333K - $450K *

Lead the charge in innovative clinical programs, shaping strategies and executing trials from first-in-human to registration, while ensuring patient safety and compliance in a dynamic regulatory envir...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Join a dynamic team to drive operational excellence across multiple manufacturing sites, fostering continuous improvement strategies and Lean practices to enhance safety, quality, delivery, and produc...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$130K - $160K *

Drive operational excellence by implementing a unified continuous improvement system across sites, enhancing productivity, and fostering a culture of accountability and innovation while collaborating...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Transform clinical quality by supporting training initiatives, monitoring clinician performance, and ensuring compliance with quality standards for successful operational processes and clinician suppo...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Transform health information management by leading end-to-end processes, ensuring compliance, and optimizing workflows. Collaborate across departments to enhance operational performance and support or...

Yesterday

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.