Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$90K - $110K *

Join our mission-driven organization as a Nursing leader, driving exceptional care quality and improving facility performance while overseeing daily operations and fostering staff development. Be part...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$91K - $109K *

Bring your leadership to enhance nursing excellence in a dynamic environment. Lead a dedicated team, oversee daily operations, and ensure regulatory compliance while providing high-quality care and pr...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$183K - $294K *

Unlock your potential as a leader in Clinical Affairs, guiding global clinical studies and driving innovative practices in diagnostics. Collaborate across teams to ensure compliance, budget management...

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $110K *

Lead clinical teams to optimize ABA therapy quality, mentor staff, and ensure individualized care for children with autism. Collaborate across functions to drive client progress and support a mission...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $110K *

Lead clinical teams to deliver high-quality ABA therapy, mentor staff, and drive client progress in a supportive, mission-driven environment focused on excellence and growth...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Empower communities by providing visionary clinical leadership in behavioral health. Collaborate with multidisciplinary teams to enhance patient care, drive quality improvement, and develop strategic...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$120K - $150K *

Champion the execution of clinical trials by managing CROs and vendors, ensuring compliance with FDA and GCP standards. Leverage your expertise to enhance project efficiency and drive collaboration ac...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $85K *

Join us to lead a regional clinical staffing business, ensuring compliance and quality in dietary services for long-term care. Collaborate with HR and stakeholders to recruit, train, and retain a skil...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Grow your leadership skills by overseeing clinical operations in the MA, CT, and RI area. This role involves managing staffing, ensuring compliance, and fostering team development in a dynamic environ...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $102K *

Empower clinical operations across the MA, CT, and RI regions, driving staffing solutions in long-term and post-acute care. Manage and train a dedicated team, ensuring compliance and excellence in die...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$116K - $193K *

Lead the charge in developing and implementing a comprehensive nursing education strategy, ensuring workforce readiness and clinical competency across the health system while collaborating with leader...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$190K - $210K *

Lead and innovate pharmacy operations, ensuring high-quality clinical services and patient-centered care. Collaborate with teams to optimize workflows, compliance, and staff development while driving...

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Shape the healthcare delivery within a correctional facility. Oversee clinical services, consult with medical staff, and ensure quality care in compliance with standards. Lead initiatives to improve p...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$151K - $208K *

Unlock potential by leading strategic sourcing initiatives and supplier management for Human Resources and Professional Services. Develop category strategies and coach a team to exceed stakeholder exp...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$151K - $208K *

Champion effective sourcing strategies and lead a dynamic team while engaging with senior stakeholders to drive procurement excellence and align business priorities with category management goals...

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$151K - $208K *

Shape the future of procurement by leading strategic sourcing initiatives, cultivating stakeholder relationships, and driving operational excellence across Human Resources and Professional Services ca...

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$175K - $210K *

Empower your career with a leadership role enhancing medical content quality. Drive collaboration among teams to ensure clinical accuracy and strategic relevance in pharmaceuticals and healthcare mark...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $150K *

Unlock potential by leading a dynamic Project Management team to enhance agency workflows, drive efficiency, and foster collaboration across departments, ensuring high-quality deliverables from planni...

Today

  •   8 - 10 years exp.  •   Media

$240K - $275K *

Champion profitable coverage access with key government accounts and regional plans. Collaborate across teams to support Market Access objectives and enhance patient and provider experiences in this s...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Unlock potential by leading financial planning and analysis for site operations, collaborating with cross-functional teams, and driving strategic initiatives to enhance business success and operationa...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Lead dynamic medical writing initiatives while enhancing quality control processes and managing client relationships. Collaborate cross-functionally to drive improvements, oversee resource management...

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$220K - $250K *

Unlock strategic opportunities in patient advocacy and engagement. Drive impactful initiatives for Systemic Mastocytosis while collaborating across teams to uplift patient voices and foster partnershi...

Reposted 6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$143K - $193K *

Empower global clinical operations by leading process management initiatives, ensuring compliance and efficiency. Collaborate with cross-functional teams to enhance quality and drive innovations in cl...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Elevate your career by managing national clinical trials for innovative stroke treatments. Collaborate with diverse teams, oversee project timelines, and ensure regulatory compliance while driving cli...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$284K - $385K *

Join a team that's shaping the future of oncology by leading clinical trials for solid tumors. You'll design study concepts, oversee trials, and collaborate with experts to drive impactful drug develo...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.