Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$121K - $202K *

Drive global security innovation by leading the design and execution of comprehensive security programs, enhancing protection for personnel and assets across all organizational operations worldwide...

4 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$121K - $202K *

Join our team to drive the global security technology strategy and lead the GSOC program, ensuring the protection of employees and assets through innovative security solutions and operational excellen...

4 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$136K - $218K *

Transform patient care delivery by leading clinical nursing operations, ensuring compliance, and fostering interdisciplinary collaboration to achieve excellence in service and patient satisfaction...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$136K - $218K *

Drive excellence in clinical nursing management, overseeing patient care delivery, resource management, and compliance. Collaborate with interdisciplinary teams to enhance service quality and achieve...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$183K - $269K *

Lead the charge in safety monitoring and governance for assigned products, ensuring effective signal detection, risk management, and regulatory compliance while collaborating with cross-functional tea...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$97K - $180K *

Join a team that's dedicated to optimizing healthcare operations and provider performance. You'll manage recruitment, enhance clinical quality, and ensure financial growth while leading a passionate t...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $220K *

Lead financial strategy for manufacturing operations, driving insights and optimizing costs. Collaborate with senior leadership to enhance productivity and reporting, ensuring financial performance al...

1 week ago

  •   8 - 10 years exp.  •   Staffing

$160K - $200K *

Empower your career by leading the integration of clinical trial operations and SaaS platform development. Drive innovation and efficiency in a collaborative environment, bridging operational workflow...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$101K - $134K *

Pioneer the growth of wound care programs by overseeing operations, staff management, financial oversight, and community engagement, within a collaborative healthcare environment focused on innovative...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$82K - $109K *

Grow your career with expert leadership in wound care management. Oversee operations, enhance quality, and drive community engagement for optimal patient outcomes in a collaborative healthcare setting...

Reposted 1 month ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Elevate integrated psychiatric services as a strategic leader, guiding provider development and innovative care solutions, while driving community partnerships for enhanced patient outcomes and organi...

1 month ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$232K - $331K *

Deliver impactful leadership in clinical operations, overseeing 24/7 command centers and driving strategic initiatives to enhance patient care and operational efficiency in a high-stakes environment...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Transform the future of nursing operations by leading a dedicated team, ensuring high-quality patient care, and implementing innovative practices while maintaining compliance with healthcare standards...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $90K *

Unlock potential by providing leadership and direction in human services, ensuring quality operations and compliance while fostering relationships with families and professionals to enhance service de...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $165K *

Transform healthcare operations by enhancing patient care quality and efficiency. Collaborate with leadership to implement strategic initiatives, manage staff performance, and optimize financial outco...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Empower operational excellence by managing financial resources, staff development, and compliance. Drive process improvements and strategic planning to enhance departmental efficiency and support the...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Lead legal and risk operations, ensuring compliance and integrity across domestic and international initiatives. Collaborate with stakeholders to manage contracts, develop policies, and support govern...

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Lead the charge in delivering high-quality rural healthcare by overseeing nursing and clinical operations. Engage with staff and patients to ensure compliance and enhance patient care standards in a d...

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Lead the rehabilitation department, ensuring excellence in patient care, team performance, and compliance. Drive strategy, oversee operations, and foster collaborations to achieve financial goals whil...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Lead and manage the rehabilitation department, ensuring high-quality resident care while achieving financial and regulatory goals. Drive excellence in patient services, employee engagement, and operat...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $100K *

Join a team that's dedicated to elevating rehabilitation services and exceeding care standards. Drive patient care quality, foster team development, and navigate departmental operations to achieve bot...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$92K - $110K *

Transform patient care by leading our rehabilitation department, ensuring compliance and excellence in service delivery while driving financial performance and fostering team collaboration...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Champion excellence in rehabilitation services by leading a dedicated team, ensuring compliance with regulations, and enhancing patient care while achieving financial goals and fostering collaboration...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Lead the rehabilitation department, ensuring high-quality patient care while achieving financial and regulatory goals. Drive team performance, foster collaboration, and uphold professional standards t...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Lead the charge in enhancing rehabilitation services, ensuring top-tier patient care while aligning with financial and regulatory standards. Drive team performance and foster collaboration to achieve...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.