Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
$80K - $96K *
Lead clinical services to enhance patient care and operational efficiency while supervising staff and fostering collaboration with medical teams. Drive quality improvement initiatives and ensure compl...
4 weeks ago
$110K - $115K *
Join a dedicated team overseeing clinical programs for adolescents facing severe mental health challenges. Lead staff, enhance service quality, and ensure compliance with accreditation standards in a...
Today
Senior Director, Clinical Science, Early-Stage Clinical Development
$244K - $305K *
Join a dynamic team as a Senior Director in Clinical Science, leading innovative drug development strategies. Drive clinical plans, mentor professionals, and collaborate cross-functionally to deliver...
1 week ago
Clinical Operations Director RN, Hospice
$145K - $165K *
Transform clinical operations by leading, supervising, and ensuring compliance in patient care services while collaborating with interdisciplinary teams to enhance overall care quality...
4 weeks ago
Manager, Pharmacovigilance (US)
$90K - $178K *
Shape the future of pharmacovigilance by leading teams to ensure compliance and operational excellence in global clinical trials, while advancing patient safety through effective oversight and mentors...
Yesterday
Manager, Pharmacovigilance (US)
$90K - $178K *
Lead and develop a high-performing pharmacovigilance team, ensuring compliance and operational excellence across global clinical trials. Influence patient safety initiatives and drive project delivery...
Yesterday
Manager, Pharmacovigilance (US)
$90K - $178K *
Drive excellence in pharmacovigilance by leading teams and ensuring compliance with global safety regulations. Influence patient safety initiatives while managing project delivery across diverse clini...
Yesterday
Manager, Pharmacovigilance (US)
$90K - $178K *
Drive excellence in pharmacovigilance by leading teams and projects, ensuring compliance and safety across clinical trials. Leverage scientific expertise and operational oversight to mentor profession...
2 days ago
Clinic Director/Physical Therapist
$90K - $110K *
Elevate patient care by leading a dynamic physical therapy clinic. Oversee operations, staff development, and patient satisfaction while driving growth and compliance. Build strong relationships with...
2 weeks ago
Clinic Director/Physical Therapist
$80K - $95K *
Shape the future of patient care by leading a dedicated team of therapists, delivering personalized treatment plans, and fostering meaningful relationships in a supportive, collaborative environment f...
2 weeks ago
Clinic Director/Physical Therapist
$80K - $95K *
Inspire patient-first care as a Clinic Director, leading a dedicated team to provide individualized treatment, foster relationships, and enhance clinical growth within a supportive environment focused...
3 weeks ago
Clinic Director/Physical Therapist
$80K - $95K *
Join a dynamic team as a Clinic Director, overseeing operations, enhancing patient care, and fostering staff development. Drive clinic growth while ensuring compliance and building strong relationship...
2 weeks ago
Sr. Director of Clinical Training
$110K - $130K *
Join a team that's dedicated to enhancing clinical training for psychology interns. Oversee program coordination, maintain accreditation, and develop strategic partnerships to ensure a high-quality tr...
1 week ago
$170K - $210K *
Shape the future of implementation by leading a skilled team for strategic client launches, ensuring timely delivery and quality outcomes while refining processes to enhance efficiency in a rapidly gr...
3 weeks ago
$100K - $120K *
Transform nursing services through strategic leadership, ensuring compliance, quality improvement, and patient-centered care across all locations while mentoring clinical staff and enhancing operation...
1 week ago
$182K - $198K *
Build and lead a robust Service Management Office to enhance IT operations, ensuring effective governance, accountability, and continuous improvement across a complex 24x7 environment, while fostering...
1 week ago
$168K - $264K *
Drive the development of mechanistic models to guide RNA therapeutic design, collaborating closely with chemists and biologists to enhance siRNA efficacy across various disease programs through advanc...
3 days ago
Director, Project Management - Operations
$120K - $145K *
Transform the future of healthcare operations by leading strategic projects that enhance patient care, optimize processes, and drive revenue growth across multi-site practices. Collaborate with stakeh...
3 weeks ago
Director, Project Management - Operations
$110K - $130K *
Lead strategic initiatives to enhance operational efficiency and patient experience across multi-site healthcare operations. Collaborate with stakeholders to drive measurable improvements in revenue a...
3 weeks ago
Director of Clinical Risk Management
$85K - $100K *
Shape a culture of safety and accountability by leading and enhancing the clinical risk management program, while collaborating with clinical leaders to mitigate risks and improve processes across the...
4 weeks ago
Executive Director Acute Rehabilitation Services
$161K - $235K *
Empower transformative clinical excellence in rehabilitation services, leading a dynamic team to enhance patient care and operational efficiency across multiple facilities while fostering collaboratio...
Today
$180K - $220K *
Transform medical strategies by leading a team of experts, ensuring compliance and scientific accuracy in communications, and fostering client relationships to drive innovative healthcare solutions...
1 week ago
$210K - $250K *
Unlock your potential by leading medical strategies in a dynamic environment. Drive compliance, mentor a talented team, and collaborate with clients to ensure scientific accuracy in promotional materi...
1 week ago
Senior Manager, Virtual Care Operations
$120K - $140K *
Lead and optimize daily operations of a Care Concierge team, ensuring performance meets SLAs while managing staffing, training, and development across a 24/7 environment. Drive efficiency and enhance...
1 week ago
Senior Manager, Virtual Care Operations
$120K - $140K *
Shape the future of healthcare operations by leading a dynamic team, ensuring optimal performance and patient satisfaction across a 24/7 Care Concierge function while driving continuous improvement an...
1 week ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.