Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$85K - $110K *

Unlock potential by leading our outpatient clinic, enhancing patient care, and fostering community relationships. Drive growth and operational excellence while mentoring a dedicated team in a supporti...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $110K *

Transform the patient care experience by leading an outpatient orthopedic therapy team, ensuring optimal functionality and well-being for an active community. Drive growth and collaboration while fost...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $110K *

Lead and manage an outpatient orthopedic therapy center, ensuring exceptional patient care and team development while fostering community partnerships for optimal outcomes and growth...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $190K *

Champion innovative medical strategies to enhance patient care and support product launches in Neuroscience. Collaborate with cross-functional teams to drive educational initiatives and ensure complia...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $190K *

Lead the charge in strategic medical affairs for a Neuroscience portfolio, driving initiatives that enhance patient safety and therapeutic value. Collaborate with cross-functional teams to support pro...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $190K *

Join a team that's dedicated to enhancing patient care through strategic medical affairs initiatives. As a Scientific Director, you'll lead efforts in the Neuroscience portfolio, collaborating with cr...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $190K *

Empower your career by leading strategic medical initiatives in Neuroscience. Collaborate with cross-functional teams to enhance patient safety and drive educational efforts while managing key project...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $190K *

Shape the future of medical affairs by leading strategic initiatives in Neuroscience. Collaborate with cross-functional teams to enhance patient safety and drive impactful educational programs while m...

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $190K *

Transform medical affairs by providing strategic insights and scientific expertise for the Neuroscience portfolio. Collaborate with cross-functional teams to enhance patient safety, support product la...

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$161K - $269K *

Shape the future of medical drug contracting by leading strategic initiatives, enhancing client relationships, and driving innovative solutions across health plans and employer groups while managing a...

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$161K - $269K *

Lead the charge in developing innovative medical drug contracting solutions, collaborating with cross-functional teams to enhance client relationships and drive growth across health plans and employer...

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$161K - $269K *

Lead the development of innovative medical drug contracting solutions, collaborating with internal and external partners to enhance offerings for Health Plans and Employer Groups, while driving client...

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Lead the charge in implementing clinical models across diverse markets, managing multiple projects from kickoff to go-live. Drive results through cross-functional collaboration and ensure compliance w...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Lead patient care by performing comprehensive assessments, diagnosing conditions, and prescribing treatments while ensuring adherence to safety protocols and delivering compassionate service in a clin...

Today

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Manage and optimize ambulatory operations for a multi-site cardiology network, ensuring high-quality patient care and financial performance while leading a diverse team and driving strategic growth in...

3 days ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$155K - $194K *

Elevate program management by ensuring effective operations for clinical development teams. Collaborate with leaders to streamline processes, manage timelines, and foster a cohesive team environment...

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Shape the future of clinical services by leading a dedicated team, enhancing program quality, and ensuring compliance. Drive growth through strategic planning, staff development, and effective communi...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$120K - $150K *

Champion operational excellence in patient registration and admitting, driving financial performance and enhancing the patient experience through strategic leadership and collaboration across departme...

1 week ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$254K - $308K *

Drive impactful global medical strategy for psychiatry, oversee execution of medical activities, foster cross-functional collaboration, and lead a high-performing team in mood disorder product develop...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Transform patient care by providing clinical leadership and oversight in skilled nursing and long-term care facilities. Collaborate with interdisciplinary teams to ensure high-quality, patient-centere...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Empower supply chain excellence by leading process redesign and Lean initiatives. Collaborate with clinical teams to optimize operations, reduce costs, and enhance service delivery while ensuring comp...

2 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$95K - $115K *

Join a team that's dedicated to enhancing patient care within an inpatient behavioral health unit. Lead clinical and administrative staff to maintain high standards of care, oversee policy implementat...

Reposted yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Join a team that's shaping organizational growth by partnering with leaders to develop talent strategies, enhance workforce effectiveness, and drive employee engagement. This strategic role blends han...

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Shape the future of clinical care by leading and mentoring nursing teams across multiple facilities. Drive compliance, quality outcomes, and excellence in resident care while fostering professional de...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$230K - $275K *

Oversee regional dialysis operations, ensuring quality patient care, compliance, and financial performance. Lead a diverse team, implement strategic initiatives, and drive operational efficiencies to...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.