Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$110K - $130K *

Champion the clinical departments of an ambulatory surgical center by overseeing staff development, quality assurance, and strategic growth initiatives. Utilize critical thinking and emotional intelli...

Today

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Unlock potential by leading clinical operations in an ambulatory surgical center. Oversee staff development, ensure quality assurance, and drive program growth while fostering effective communication...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Lead day-to-day operations of the surgical center, enhancing patient care and efficiency through strategic initiatives, staff management, and compliance oversight while fostering a collaborative envir...

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Drive operational excellence in an Ambulatory Surgical Center by overseeing daily functions, enhancing patient care, and implementing strategic initiatives to improve efficiency and staff performance...

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Join a team that's dedicated to delivering exceptional patient care in a fast-paced surgical environment. Lead nursing operations, ensure quality service, and collaborate with medical staff to enhance...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Unlock your potential as a Clinical Director, overseeing operations and enhancing patient care in a dynamic ASC environment. Collaborate with leadership to drive efficiency, compliance, and staff deve...

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$220K - $270K *

Drive the strategic planning and execution of clinical trials, overseeing resources and cross-functional teams to ensure delivery meets timelines, budgets, and quality standards while fostering strong...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$99K - $115K *

Transform clinical outcomes and team performance as a strategic leader, overseeing operations, enhancing quality, and mentoring a dedicated staff of clinicians to drive excellence in service delivery...

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$99K - $115K *

Champion high-quality clinical services by leading teams, enhancing performance, and driving operational success in a supportive environment committed to excellence and growth within the behavioral he...

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$164K - $246K *

Lead the charge in optimizing operational processes and training within Development, ensuring efficiency, compliance, and continuous improvement through standardized practices and effective stakeholde...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Empower clinical excellence by leading quality initiatives across 5,500+ providers in diverse ambulatory settings. Collaborate with operational leaders to enhance patient care and drive performance im...

Today

  •   Less than 5 years exp.  •   Healthcare

$255K - $290K *

Elevate clinical development by driving innovative RNAi programs, providing medical and scientific leadership, and ensuring strategic alignment with corporate objectives while fostering cross-function...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$143K - $206K *

Transform healthcare delivery by leading clinical operations, ensuring quality patient care, and fostering strategic partnerships. Drive continuous improvement and operational excellence while managin...

Kamloops, BCIn-Person

6 days ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$141K - $202K *

Join a team that's dedicated to enhancing clinical operations and patient care. Lead strategic initiatives, manage resources, and foster partnerships to ensure quality service delivery and continuous...

Cranbrook, BCIn-Person

1 week ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$150K - $180K *

Join a team that's dedicated to ensuring GMP compliance and quality in manufacturing, QC, and supply chain operations. Lead with a focus on risk management, regulatory readiness, and continuous improv...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$200K - $235K *

Join a team that's redefining clinical operations by leading global trials, ensuring compliance, and driving project success in a fast-paced environment. Collaborate with cross-functional teams to del...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Manage and elevate the clinical department, overseeing staff, programs, and daily operations. Drive quality care and compliance while fostering a supportive environment for patient treatment and staff...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $127K *

Champion your career by leading clinical operations in a dynamic, supportive environment. Collaborate with a diverse team to enhance service delivery, ensure compliance, and drive initiatives that imp...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $100K *

Transform clinical operations by leading a dedicated team, ensuring high-quality care, and fostering professional development while collaborating with administration and stakeholders to enhance progra...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$170K - $190K *

Join a team that's transforming behavioral health care delivery through innovative leadership and strategic oversight. Drive operational excellence and improve client outcomes across multiple sites wh...

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Lead strategic and operational initiatives for a research center, ensuring efficient administration, financial management, and compliance. Collaborate with stakeholders to enhance research productivit...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $150K *

Shape the future of oncology research by leading clinical trials and enhancing their quality. Drive program growth, manage multi-site operations, and ensure compliance with regulations while mentoring...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K *

Join our therapy team to enhance client outcomes through effective supervision, collaboration, and innovative behavior analytic strategies. Drive growth and stability while ensuring compliance with tr...

Today

  •   Less than 5 years exp.  •   Healthcare

$100K *

Unlock potential by leading a dedicated therapy team to enhance client outcomes through effective supervision, collaboration, and implementation of behavior analytic strategies across multiple locatio...

Today

  •   Less than 5 years exp.  •   Healthcare

$100K *

Transform client outcomes by leading a dedicated therapy team, ensuring effective treatment plans and supervision while fostering collaboration across disciplines to enhance quality of life for youth...

Today

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.