Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$110K - $130K *

Lead the charge in optimizing clinical operations, ensuring effective patient care delivery, staff development, and compliance with regulatory standards while enhancing profitability and operational e...

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $195K *

Innovate member experience strategies by translating enterprise goals into actionable plans. Drive performance improvements in CAHPS and HOS programs through provider engagement and data analysis, ens...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$242K - $282K *

Lead the oversight of contractual matters across departments, serving as a trusted advisor to internal stakeholders from pre-clinical to commercial readiness. This role emphasizes collaboration and ex...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Lead the coordination and implementation of hospice services, ensuring high-quality patient care while managing a dedicated care team in a safe and cost-effective manner...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Transform patient care as a Director of Operations (RN), leading a dedicated team to deliver exceptional hospice services. Oversee operations, ensuring quality and safety while fostering professional...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$200K *

Drive innovative research initiatives by providing technical expertise and strategic guidance. Lead complex projects in biology and related fields, influencing operational goals while mentoring junior...

1 week ago

  •   Less than 5 years exp.  •   Media

$110K - $130K *

Lead a dynamic clinical operations team to enhance patient care delivery, ensuring compliance and operational excellence while fostering staff development and interdisciplinary collaboration for optim...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $220K *

Reimagine operational excellence as you lead multi-state ASC strategies, drive growth initiatives, and enhance clinical performance. Collaborate with leadership to optimize patient care and achieve ma...

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$125K - $150K *

Join a dynamic team to optimize supply chain operations, ensuring efficient medication delivery from pharmacy partners to patients. Oversee systems, processes, and a team to scale operations amidst ra...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Transform enterprise growth operations by providing strategic leadership and optimizing processes. Collaborate with executives to drive performance, enhance decision-making, and lead a high-performing...

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Optimize laboratory services across acute care and ambulatory settings, providing strategic leadership to enhance clinical quality and operational excellence. Collaborate with diverse teams to drive p...

Today

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$238K - $315K *

Transform the future of patient safety by leading strategic safety monitoring and risk management initiatives for investigational and marketed products, ensuring compliance and collaboration across te...

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Drive strategic leadership in quality improvement and clinical transformation initiatives across community health centers, enhancing patient outcomes and operational performance while fostering a cult...

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$93K - $120K *

Join a dynamic team as you manage clinical data throughout study lifecycles, ensuring compliance and quality. Collaborate with cross-functional teams to drive data strategy and support innovative solu...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$195K - $255K *

Elevate program execution by translating strategic plans into actionable timelines. Collaborate across functions to ensure alignment, manage risks, and drive decisions, while leveraging AI tools for e...

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$210K - $250K *

Innovate in AI-native primary care by leading a dynamic medical group. Manage physicians, enhance care delivery, and shape clinical programs while maintaining direct patient care involvement. Drive ex...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$300K - $350K *

Champion high-quality, patient-centered care by leading clinical initiatives, enhancing performance standards, and fostering collaboration among medical staff to ensure optimal patient experiences and...

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Lead clinical pharmacology strategies and drive innovative modeling to enhance drug development. Collaborate cross-functionally to integrate pharmacokinetic insights into global plans, ensuring regula...

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$129K - $205K *

Lead the charge in shaping clinical strategy across a vast network of dialysis clinics, driving quality outcomes and patient safety while mentoring clinical leaders and fostering collaboration with ke...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$129K - $205K *

Unlock potential by leading clinical strategy across a vast network of dialysis clinics. Drive quality outcomes, enhance patient safety, and foster talent development while collaborating with executiv...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Champion the vision and strategy for a key business portfolio, driving product outcomes and team performance while ensuring alignment with company goals and market needs. Lead a high-performing team t...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$75K - $90K *

Contribute to impactful substance abuse programs by leading clinical teams, ensuring compliance with regulations, and promoting innovative treatment approaches within a dynamic care continuum from Det...

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$110K *

Join a team that's dedicated to delivering high-quality psychiatric care while enhancing practice operations. Balance direct patient care with leadership responsibilities to drive efficiency and suppo...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$159K - $211K *

Join us in transforming quality operations by leading a robust PACE quality program, ensuring compliance and care excellence while collaborating cross-functionally to enhance participant outcomes and...

California, USRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Develop and implement efficient SOPs and systems in media operations, enhance workflows, and drive resource allocation, ensuring seamless collaboration and compliance across teams while fostering a cu...

4 weeks ago

  •   5 - 7 years exp.  •   Media

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.