Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$150K - $175K *

Join a dynamic team to oversee clinical trials, ensuring excellence in design and execution. Provide strategic leadership and manage resources across projects to uphold regulatory compliance while fos...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $220K *

Transform patient care by leading medical initiatives and coordinating treatment plans to promote the highest quality of health in residents. Collaborate with healthcare teams to enhance nursing progr...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Advance clinical excellence by providing leadership and oversight in skilled nursing and long-term care facilities, ensuring high-quality, patient-centered care through collaboration with interdiscipl...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $190K *

Lead strategic operations and analytics within Global Medical Affairs, ensuring excellence in project execution and data-driven insights. Collaborate cross-functionally to align initiatives with corpo...

5 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$160K - $190K *

Transform Global Medical Affairs by leading operations and analytics, ensuring strategic alignment and data-driven decisions. Drive excellence across teams, manage budgets, and foster collaboration to...

6 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$210K - $250K *

Transform patient care by leading and coaching Primary Care providers while ensuring clinical excellence and operational efficiency in a collaborative environment that integrates behavioral health ser...

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$160K - $200K *

Drive innovation by leading integration engineering for healthcare AI, ensuring seamless EHR connectivity and operational excellence. Collaborate across teams to enhance patient engagement tools and m...

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$154K - $431K *

Elevate your career by providing expert medical guidance in dermatology, supporting clinical trials and project delivery. Collaborate with teams to ensure patient safety and protocol adherence while e...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Join us in leading the development and execution of comprehensive risk management strategies. Collaborate with executive leadership to identify and mitigate enterprise risks, ensuring organizational r...

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $180K *

Lead the charge in developing and implementing risk management strategies to identify, assess, and mitigate enterprise risks, ensuring alignment with organizational goals and compliance requirements w...

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$144K - $160K *

Champion operational excellence by leading teams to enhance efficiency and care delivery. Drive AI integration, manage P&L, and collaborate cross-functionally to support growth and sustainability in h...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$115K - $198K *

Join us to lead innovative clinical programs, enhancing care solutions across oncology and cardiovascular disease. Collaborate with stakeholders to improve member experiences and clinical outcomes whi...

Yesterday

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$115K - $198K *

Join a team that's dedicated to enhancing clinical programs across oncology and cardiovascular care. Lead initiatives that improve member experiences and outcomes while collaborating with key stakehol...

Yesterday

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$115K - $198K *

Join a dynamic team as you lead innovative clinical programs, enhancing care solutions across oncology and cardiovascular disease. Collaborate with stakeholders to improve member experiences and clini...

Yesterday

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$115K - $198K *

Empower healthcare innovation by leading clinical programs for oncology and cardiovascular care. Drive strategic partnerships, enhance member experiences, and optimize outcomes through comprehensive m...

Yesterday

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$115K - $198K *

Lead the development and management of comprehensive clinical programs, enhancing care solutions for oncology and cardiovascular conditions. Collaborate with stakeholders to improve member experiences...

Yesterday

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$115K - $198K *

Drive innovative clinical programs across oncology and cardiovascular care, enhancing member experiences and outcomes. Collaborate with stakeholders to develop integrated solutions and manage national...

Yesterday

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$115K - $198K *

Champion innovative clinical solutions by managing comprehensive care programs across oncology and cardiovascular disease. Collaborate with stakeholders to enhance member experiences and clinical outc...

Yesterday

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Empower clinical excellence while leading a dynamic BCBA team. Drive quality care, foster communication, and ensure high standards in clinical deliverables. Make a meaningful impact on growth and coll...

3 weeks ago

  •   Less than 5 years exp.  •   Staffing

$212K - $333K *

Champion operational excellence in Clinical Data Management, leading strategic initiatives and fostering partnerships to ensure timely, high-quality data delivery for clinical trials. Drive innovation...

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$119K - $179K *

Advance patient care by managing clinic operations and collaborating with healthcare teams to ensure optimal service delivery and operational efficiency...

1 month ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$85K - $100K *

Unlock operational excellence by overseeing multiple healthcare centers, ensuring quality service delivery, financial performance, and a superior patient experience while fostering a motivated team en...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Lead operational excellence across multiple centers, ensuring optimal resource use, superior patient experience, and financial performance while fostering a motivated team environment and implementing...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $100K *

Advance operational excellence across multiple centers, ensuring optimal resource use, superior patient experience, and strong financial performance while leading and motivating diverse teams to achie...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Transform operational excellence across multiple centers, ensuring optimal resource utilization, superior patient experience, and financial performance while fostering a motivated team environment and...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.