Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$110K - $184K *

Support the successful execution of clinical projects by overseeing planning, resource management, and operational performance while ensuring compliance with quality and regulatory standards. Collabor...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Lead the charge in optimizing clinical business processes to drive operational excellence and compliance. Collaborate across functions to translate complex challenges into effective solutions, ensurin...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Unlock operational excellence by leading clinical process design and optimization. Drive cross-functional alignment, manage complex challenges, and ensure compliance while fostering innovation in Clin...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Manage and direct nursing practice and patient care delivery, ensuring compliance and optimal outcomes. Collaborate with leadership to set strategic goals and foster a professional environment that pr...

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$129K - $205K *

Innovate clinical outcomes through strategic leadership and cross-functional collaboration, impacting over 200,000 patients. Drive enterprise-wide transformation initiatives, empowering a high-caliber...

Reposted 6 days ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $140K *

Grow your career with a strategic HR role managing global operations, talent acquisition, and compliance. Collaborate with the executive team to drive workforce strategy while enhancing employee exper...

1 month ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Transform service delivery by leading high-performance teams, ensuring client satisfaction, and driving strategic initiatives. Collaborate across departments to enhance practice management and achieve...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Healthcare

$124K - $178K *

Transform clinical operations by leading strategic initiatives, optimizing resources, and fostering collaboration across departments to enhance performance and achieve organizational goals in a dynami...

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $135K *

Drive excellence in patient care by leading clinical activities, ensuring high standards, and cultivating a mission-driven environment, while overseeing a dedicated team focused on delivering exceptio...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$245K - $286K *

Elevate clinical quality assurance through strategic leadership and oversight of global trials, ensuring compliance with GCP regulations. Drive quality culture and inspection readiness while mentoring...

United StatesRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$143K - $178K *

Lead biomarker operations for Phase I-III oncology trials, ensuring protocol alignment, managing vendor relationships, and optimizing processes to support clinical research excellence and regulatory c...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Shape the future of patient care by leading clinical standards and quality initiatives across managed facilities, ensuring compliance and excellence in nursing care through innovative programs and pro...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$195K - $215K *

Shape the future of cell therapy by leading cross-functional teams through early-phase clinical trials. Drive program strategy, manage risks, and foster collaboration to deliver innovative therapies f...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Lead the charge in enhancing patient care by overseeing clinic operations, supervising counseling staff, and ensuring high-quality behavioral health services through effective management and teamwork...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Lead the charge in optimizing clinical supply chain strategies, ensuring seamless material availability for global trials. Collaborate with cross-functional teams to enhance operational efficiency and...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$192K - $226K *

Lead the charge in Clinical Quality Assurance, ensuring compliance and oversight across clinical studies. Drive team growth, develop audit plans, and support continuous improvement while mentoring jun...

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Transform lives by leading a dedicated team in a residential substance use treatment program, ensuring compliance and quality care while fostering a supportive environment for both staff and patients...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$130K - $160K *

Join a dynamic team to oversee Ambulatory Surgery Centers, driving operational excellence, compliance, and performance improvement while collaborating with clinical leaders to enhance service lines an...

Today

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$185K - $225K *

Join a dynamic team as you drive operational excellence in Medical Affairs. Support strategic initiatives, manage budgets, and enhance processes to ensure compliance and efficiency. Collaborate across...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Optimize analytics workflows in Clinical Operations to enhance productivity and performance insights. Collaborate on data integration, reporting, and automation, ensuring actionable insights drive str...

RemoteRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Partner with us to enhance our analytics workflows, integrating diverse data sources to drive insights for clinical operations leadership. You'll streamline reporting processes, ensuring data quality...

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $140K *

Empower customer success by leading clinical programs and strategic relationships. Drive adoption, optimize workflows, and ensure measurable outcomes while collaborating cross-functionally to enhance...

Today

  •   5 - 7 years exp.  •   Healthcare

$125K - $140K *

Lead the charge in managing strategic clinical programs and customer relationships. Drive adoption, optimize workflows, and ensure account growth while delivering measurable value and fostering collab...

Boston, MARemote

Today

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Join a dynamic team to enhance healthcare analytics by integrating diverse data sources, driving automation, and delivering actionable insights to elevate clinical operations and boost care team perfo...

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$140K - $175K *

Drive operational excellence by leading strategic initiatives and managing a team to enhance Care Operations. Transform high-level strategies into scalable systems that improve care delivery and patie...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.